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  1. Today
  2. 0_purchase.png.90e351976c60ab1694dd926e4

    Purchase

    Product Description
    Formulated with pure fermented green tea extract in lieu of distilled water, this antioxidant-rich cream is gel based to provide intense hydration without being sticky or too heavy on skin. The gel based cream contains over 63% of fermented green tea extract and allows skin to retain moisture for long hours by forming a thin hydrating layer on dry skin. Our Chock Chock collection features a special fermented Korean green tea called 'Chung TaeJeon' with over a thousand years of history, the world's first naturally fermented green tea, is fermented through sunlight for over 365 days and provides gentle yet intense moisture and hydration that lasts.

    Brand Story
    TONYMOLY is a leading K-beauty brand that fuses high-quality ingredients with innovative technology in unique and inimitable packaging.
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    $21.25 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. [BONAJOUR] Vegan beauty Organic Green Tea Natural Moisturizing Cream for dry and sensitive skin, Best Face Moisturizer_VEGAN- Anti Aging, Anti Wrinkle, Brightening/Get It Beauty best item 3.38 Fl. oz
    Power of Green Tea - Catechin and vitamin enriched Green tea ingredient protects your dry skin from aging and helps out emit residue to make your skin healthy and young. (organic green tea in Jeju Island.)
    0% of toxic chemical ingredients – Unlike Silicone oil which is well-known as chemical moisturizer, high quality natural moisturizing ingredients give full hydration to your skin in a healthy way. Paraben, Phenoxyethanol, fragrance, artificial pigment and silicone are absolutely free in Waterbomb. Your skin is supposed to be safe from them.
    Various Peptides – Different peptides regenerate your skin and support anti-aging function of your skin. Peptides enhance moisturizing, elasticity, skin-protection factors of your skin at least 4 times.
    72 Hours hydration - The best moisturizer forms moisturizing barrier to prevent your skin dry and strained for 72 hours.
    No Animal experiment – We know you are warmhearted person caring about animals. We do as well. We do not test with any type of animals. This moisturizer does not have any type.
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    $16.00 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. SeboCalm Redness Relief Face Moisturizer - Vegan Hypoallergenic Soothing Rosacea or Acne Prone Anti Itch Skin Care Cream for Facial Sensitive Oily and Combination Skin
    SOOTHES RED IRRITATED ITCHY SKIN - Extremely Calming Moisturizer Especially on Oily, Combination & Normal to Dry Face Skin. Helps Reduce Symptoms of Acne, Blemishes, Seborrheic Dermatitis & Rosacea
    PROVEN 30 YEARS ADVANCED VEGAN FORMULA - Millions of Loyal Customers Worldwide. Vitamin E & Aloe Barbadensis for Essential Anti Redness Extra Protection. Professional Oil & Sebum Control Moisturiser
    RECOMMENDED BY DERMATOLOGISTS - Dermatologically & Clinically Tested Cream Solution. Anti Itching & Anti Rash Safe Skincare Product. Hydrating Rash Reducer. Cruelty Free, no Parabens, Sulfates or Cortisone
    PRESERVES DAILY SKIN NATURAL MOISTURE - Lightweight Non Greasy & Fast Absorbing. Intense Hydration Booster. Refining Pore Minimizer. Great as Sensitive Skin Aftershave Lotion. Gentle Yet Ultra Effective
    PROMOTES A MATTE NON SHINY APPEARANCE - Luxury Moisturizing Facial Mattifier. Best for Women Cosmetic Care before Applying Beauty Makeup. Topical Treatment to Keep Skin Smooth, Soft & Healthy
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    $19.98 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. Korean Skin Care Snail Repair Cream - Korean Moisturizer Night Cream 97.5% Snail Mucin Extract - All In One Recovery Power For The Most Effective Korean Beauty Routine - 2oz
     CONSIDERED TO BE FAR more effective than other snail creams as it contains a higher concentration (97.5%) of snail mucin extract. Other snail cream products are not as potent or effective.
    GUARANTEED TO WORK - We promise you'll begin to see brighter, healthier and more youthful skin with this K beauty product within the first few days of use or your money back
    THIS KOREAN SKIN CARE snail cream is ethically harvested in a cruelty free environment. Our snails live and move about in an organic fashion just as they would in the wild
    UNLIKE OTHER SNAIL MUCIN extract, this formula is 97% Naturally Derived & 72% Organic + shea butter + organic aloe + jajoba oil + vitamin E for extremely effective results
    THIS SNAIL CREAM IS NON comedogenic, naturally anti-microbial & is packed with super nutrients that are guaranteed to provide you with a brighter more youthful complexion
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    $16.90 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. The Essentials Trio: Nourishing and Moisturizing Cleanser, Firm and Lift Regeneration Cream, Focus Renewal Eye Cream - Korean Skin Care with an Intense Focus On Healing and Repairing
    Best Korean Skin Care – Saranghae brings the power and beauty of Asian botanicals to the world. With innovative technology and ingredients, Saranghae focuses on healing, regenerating and protecting your skin
    Step 1: Clean & Moisturize Skin - The first step in the Essentials bundle is a powerful cleanser that removes makeup, oil, micro-particles and toxins, while hydrating and nourishing your face at the same time
    Step 2: Advanced Wrinkle Reduction – The second step in the Essentials bundle is our core moisturizer. This anti aging cream will help decrease the formation of free radicals and reduce damage due to oxidative stress. It’s potent and natural blend of antioxidants makes it the best anti aging face cream on the market
    Step 3: Reduce Dark Circles, Swelling & Puffiness: The third step and the most effective solution to restoring vitality, diminishing wrinkles and visibly brightening the appearance of dark circles around the eyes
    Our Promise – We promise to always use the highest quality ingredients, keep innovating on our formulas and providing you a delightful customer experience. We also offer you a 30 Day Full Satisfaction Money Back Guarantee
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    $149.00 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. Saranghae Complete 5 Step Bundle: Nourishing and Moisturizing Cleanser, Deep Radiance Essence + Serum, Firm and Lift Regeneration Cream, Focus Renewal Eye Cream and The Perfect Balance Toner
    Best Korean Skin Care – Saranghae brings the power and beauty of Asian botanicals to the world. With innovative technology and ingredients, Saranghae focuses on healing, regenerating and protecting your skin. This 5-step system bundle gives you the most complete ang-aging & nourishing experience
    Heal, Rejuvenate & Repair Your Skin – With our Complete 5 Step Bundle you receive our most comprehensive bundle and by far the most popular choice for our customers. Not only does this bundle get you the best Korean skin care routine on the market, it delivers your whole skincare routine in just 5 minutes with 5 steps
    Deep Skin Penetration To Inject Vital Nutrients – Neutralize skin cell waste by-products, repair damaged skin cell membranes, reduce wrinkle depth/width and prevent dry/flaky skin by controlling the balance between moisture and oil
    The 5 Products Included: Nourishing and Moisturizing Cleanser, Deep Radiance Essence + Serum, Firm and Lift Cellular Regeneration Cream, Focus Renewal Eye Cream and The Perfect Balance Toner. Perfect for night and day to make and keep your skin glowing
    Our Promise – We promise to always use the highest quality ingredients, keep innovating on our formulas and providing you a delightful customer experience. We also offer you a 30 Day Full Satisfaction Money Back Guarantee
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    $219.00 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. Korean Anti Aging Cream That Moisturizes, Hydrates And Rejuvenates Your Skin
    Best Korean Anti Aging Cream – As our core moisturizer, naturally derived with organic Sang Hwang mushroom and Ginseng, our Firm and Lift Cellular Regeneration cream is made to decrease the formation of free radicals and reduce oxidative stress by up to 220%. This means your skin will look beautiful while diminishing age spots, redness and visible signs of aging while fully hydrating your skin.
    Advanced Face Wrinkle Cream – Our powerful and natural blend of antioxidants, amino acids and regenerative peptides will restore the moisture of dry cracked skin. It will also Repair damaged skin cell membranes and is proven to reduce wrinkle depth and width.
    Strengthen Your Collagen And Elastin Matrix – This formula helps stop the formation of “the aging enzyme” Elastase by 85% and delivers resilient and supple skin.
    Why Saranghae? Saranghae follows ancient Korean philosophy where all products stem from herbs and plants that have incredible healing properties. Saranghae is about nurturing and caring for your skin vs. applying quick fixes (hence our 5 step anti-aging routine). Our mission is to bring the power and beauty of Asian botanicals to the world. It’s why our name “Saranghae” means “I Love You” In Korean.
    Our Promise – We promise to always use the highest quality ingredients, keep innovating on our formulas and providing you a delightful customer experience. We also offer you a 30 Day Full Satisfaction Money Back Guarantee.
    Sang Hwang Mushroom (Phellinus Linteus) • Genseng • Tea Tree extract
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    $75.00 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase. Hellocell Premium Soothing Cooler Anti-Heat Essence Mist
    LOWER DOWN high skin temperature by patented Soothing Cooler
    Long lasting moisture with jelly type mist
    The blue capsules provide high moisture to skin
    Immediately reduces skin temperature from external stresses
    RECOMMENDED TO THOSE
    Various usage on skin types
    For dry and sensitive skin : use as a mist to moisturize and soothe the skin frequently.
    For combination type skin : use as a 'high moisturizing toner' instead of general toner.
    For oily skin : use as a light soothing gel to balance the oil & hydration level of the skin.
    If skin temperature increase 1℃, then sebum increases by 10%. It takes away moisture when the skin temperature increases. In addition to excessive sebum, causes redness and troubles in the skin, and reduces elasticity, resulting in wrinkles and aging easily. Natural ingredients such as yam, aloe vera, and kombu cooling down the skin temperature to prevent moisture evaporation and reduces stimulation - Matricaria Flower Extract - Matricaria Flower Extract

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    $19.00 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

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    Purchase - Hellocell Tea Tree Spot Patch - Premium, Salicylic Acid, Invisible, Spot Cover, Acne, Pimple, Blemish, Face, Korean, 30 Round Patches  
    Thin, transparent patches_intensive care for skin trouble
    Calming down angry skin_Tea tree oil & Salicylic acid
    With excellent anti-inflammatory effects. Removing dead skins to care the acne effectively
    Troubles pre-care by sebum control, hydrating_Witch Hazel & Propolis
    Adjusting sebum and supplying moisture to the area where it tickles or pimples have just started.

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    $4.50 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

  11. There are several acne treatments used to treat rosacea, i.e., Dapsone, Sarecycline, Azithromycin, Minocycline, and the list continues, not to mention the plethora of over the counter acne treatments to consider. A typical example of an acne treatment, Benzaclin, that is also used to treat rosacea is discussed in the following paper: “Based on the theory that rosacea shares the same inflammatory features of acne, a recent study showed that, just as the combination of benzoyl peroxide 1 percent and clindamycin 5 percent gel is a powerful treatment modality for reducing Propionibacterium acnes levels, it also significantly reduces the papules and pustules of rosacea, according to Debra L. Breneman, M.D..… ‘Benzaclin, once daily, was found to be well tolerated and effective in the reduction of papules and pustules in patients with rosacea,’ said Dr. Breneman. ‘This lends credence to the theory that P. acnes is a potential aggravating factor in rosacea. This gives dermatologists a very effective treatment for rosacea.’ ” [1] Herbal Extracts for Acne One report on the 'clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris' concludes, "This herbal extracts can be a new therapeutic option for patients with mild to moderate acne vulgaris who are reluctant to use drugs." [2] The herbal extracts include: Mangosteen extract Lithospermum officinale extract Tribulus terrestris L. extract Houttuynia cordata Thunb extract End Notes [1] Dermatology Times Publish date: Apr 1, 2003 P. Acnes Possible Factor in Rosacea BenzaClin a significant Tx in lesion reduction Beth Kapes Another example similar to above paper discussing topical benzoyl peroxide 5%/clindamycin 1% (BP/C) gel (BenzaClin) concluded, "These results showed that BP/C was significantly more effective than vehicle in improving papules and pustules associated with rosacea.' Cutis. 2004 Jun;73(6 Suppl):11-7. Photographic review of results from a clinical study comparing benzoyl peroxide 5%/clindamycin 1% topical gel with vehicle in the treatment of rosacea. Leyden JJ, Thiboutot D, Shalita A. [2] J Dermatolog Treat. 2019 Oct 16:1-5. doi: 10.1080/09546634.2019.1657792. [Epub ahead of print] Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial. Yang JH, Hwang EJ, Moon J, Yoon JY, Kim JW, Choi S, Cho SI, Suh DH.
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    Purchase
    AC CURE NO PAIN NO GAIN SPOT CREAM: With stinging sensation!
    AC CURE NO PAIN NO GAIN SPOT CREAM with Phytosilica may produce a stinging sensation during use. This sensation is attributed to the process of Phytosilica taking effect in providing soothing skin care.
    Do not use a cotton swab or other tool for absorption. Only use your hand.
    1) Wash your face completely. 2) Use clean hand. 2) Apply AC Cure No Pain No Gain Spot Cream with your clean finger. 3) To get the better and faster result, rub the cream with your finger firmly.
    Active ingredients: Teatree, Centella / Cica, Niacinamide. The superior calming ingredients work in combination with Phytosilica to permeate the skin for fast soothing care.

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    Product description
    Ingredients: Water, Butylene Glycol, Silica, Niacinamide, Glycerin, Lithospermum Erythrorhizon Root Oil, Caprylic/Capric Triglyceride, Glyceryl Stearate, Macadamia Integrifolia Seed Oil, Carthamus Tinctorius (Safflower) Seed Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Argania Spinosa Kernel Oil, Sodium Hyaluronate, Orbignya Oleifera Seed Oil, PEG-100 Stearate, Polysorbate 60, Cetearyl Alcohol, Sorbitan Stearate, Propylene Glycol, Stearic Acid, Carbomer, Triethanolamine, 1,2-Hexandiol, Polyglutamic Acid, Methionine, SErine, Histidine, Hydroxyethyl Ethylcellulose, Tocopherol, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, CAmellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Chamomilla Recutita (Matricaria) Flower Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Portulaca Oleracea Extract, Calcium Pantothenate, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Pyridoxine HCI, Maltodextrin, Sodium Starch Octenylsuccinate, Citrus Aurantium Bergamia (Bergamot) Leaf Extract, Lavandula Angustifolia (Lavender) Flower Extract, Rosa Centifolia Flower Exract, Bacopa Monniera Extract, Hydroxyethylcellulose, Octanediol, Ethylhexylglycerin, Citrus Grandis (Grapefruit) seed Extract, Artemisia Priceps Extract, Belamcanda Chinensis Root Extract, Allantoin, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Dimethyl Sulfone, Adenosine, Phellodendron Amurense Bark Extract, Coptis Chinensis Root Extract, Aloe Barbadensis Leaf Extract, Luffa Cylindrica Fruit Extract, Alcohol, Dryopteris Filix-Mas Root Extract, Hydrogenated Lecithin, Ceramide NP, PEG-10 Rapeseed Sterol, Dipropylene Glycol, Glycereth-20, Dipotassium Glycyrrhizate, Disodium EDTA, Salicylic Acid, Phenoxyethanol

    $18.80 NOTE: Our shopping cart is disabled. We are using it to display affiliate items which if you click on PURCHASE in the PRODUCT INFORMATION by scrolling below or click on the Amazon banner the RRDi receives a small affiliate fee upon completion of your purchase. Mahalo.

  13. Yesterday
  14. Last week
  15. image courtesy of WikiMedia Commons The RRDi financial situation is continuously posted at this url and as of this date, March 30, 2020, we have $771.42 in the bank. Based upon how we are spending donations (the income includes the small amount of affiliate fees we receive from Amazon) we will run out of funds in several months. So we are concerned about this and decided to first post this on our website before using the newsletter tool and send this same announcement to the members who have opted to receive our newsletter. You may wonder how much we are spending in donations currently and for the first three months of 2020 we averaged our expenses to $164/month. You can view how we spent donations for last year here. So you can see our current funds will only last us several months at the present rate of expenditure. So let's compare this with how much money the NRS spends its donations (who is one of the other non profit organizations for rosacea). The only way we can get an idea how the NRS spends its donations is to look at the last financial report filed by the NRS as shown on Form 990 that the NRS files with the Internal Revenue Service for 2018 which is available for public viewing (the NRS releases its 2019 Form 990 much later and when it does we always review it since we have been reviewing how the NRS spends its donations since 1998). So let's compare how the NRS spends it donations, that is, the amount each month is spent with what the RRDi spends each month. For 2018, the NRS received in donations a total of $465,042. During this same period the NRS spent a total of $601,532 (yes the NRS can spend more than it takes in because of the assets they own which the NRS draws upon when the expenses are greater than donations). So on average, in 2018 the NRS spent over $50,000 each month! What did the NRS spend most of it donations on? The answer if you investigate is $432,408 was spent for the year (over $36,000 each month on average) on two private contractors owned by the director/president of the NRS, Sam Huff. So if you are happy with how the NRS is spending its donations that is just one of the other non profit organizations for rosacea that will continue if the RRDi runs out of funds and can't pay our monthly expenses. So the comparison is: RRDi spends NRS spends $164/month $50,000/month (of this amount $36,000 is spent on two private contractors owned by Sam Huff) Just for the record, the NRS claims on its Form 990 for 2018 that 25.31% of the total donations received in 2018 were from public support. What is one of the most interesting revelations found on the from its Form 990 for 2018 report is that it reveals how much money was received from the pharmaceutical companies which is shown in a screen shot below: The above screen shot doesn't reveal for how long a period each of the above pharmaceutical companies have been giving the NRS 'excess contributions' but it does reveal the amounts. So if you are happy the way these pharmaceutical companies are contributing to the NRS and the way the NRS is spending its contributions and if the RRDi runs out of funds to keep going, you will surely have the NRS since it has lots of money to spend, especially on two private contractors owned by Sam Huff, the director/president of the NRS. So it is simply up to you whether you want the RRDi to keep going or simply dissolve because of lack of funds. If you want to help out the RRDi there are two options, (1) donate, or, (2) volunteer (and help us get donations). If you have any questions or concerns, why not find the green reply button and post?
  16. image courtesy of Free paper chain v.2 Stock Photo We obviously aren't sure of what community support means to you, but we are trying to figure that out by forming a NON PROFIT organization for rosacea patient advocacy and encouraging rosaceans to come together by joining the RRDi and taking steps to obtain and disseminate community support for those who are suffering from rosacea. What has the RRDi done in this regard? (1) Creating a website with pages of information, a forum of rosacea topics, a community support category, member driven rosacea blogs, galleries and clubs. (2) Journal of the RRDi and the ability for anyone (amateur or professional) to submit a paper on rosacea to be published. (3) A legal non profit organization to allow donations to be tax deductible. (4) Education grants and the ability to volunteer as a grant writer for your non profit organization. (5) A way for you to volunteer to help rosacea sufferers. (6) Attracting sponsors to support our non profit organization. (7) Instructions on how to use our forum. So, what does community support mean to you? Please find the green reply button and post what it means to you? We would love to understand your concerns. You may think that posting in a community of rosacea sufferers your experience with rosacea and getting some feedback is what community support means to you? If so, this is the correct forum category to do that by finding the green reply button and post your concern.
  17. "In a statement released Sunday night, the U.S. Department of Health and Human Services announced it had received 30 million doses of hydroxychloroquine sulfate and one million doses of hloroquine phosphate donated to a national stockpile of potentially life-saving pharmaceuticals and medical supplies. Hydroxychloroquine and chloroquine, which are oral prescription drugs used primarily to prevent and treat malaria, are both being investigated as potential therapeutics for COVID-19." Coronavirus live updates: FDA gives anti-malaria drugs emergency approval to treat COVID-19 The two drugs are being investigated as potential treatments for COVID-19., By Morgan Winsor and Emily Shapiro, March 30, 2020, 8:05 AM, ABC News Virus has never been ruled out in rosacea.
  18. This question was asked and I am sharing my answer here as well. Basically everyone has demodex mites and it has been thought that the mites have some sort of undisclosed symbiotic relationship, i.e., the mites eat sebum which helps the mites and helps the humans keep sebum stasis. One report states, "....Demodex mites were originally perceived to be commensals, having a symbiotic relationship with the human host." - See Jarmuda et al published in the Journal of Medical Microbiology (second article mentioned in this post). While this same report says that 'most human populations' have NOT been sampled for demodex mites the general belief is that demodex are common throughout humanity and pose no problem as a pathogen except in the case of demodectic rosacea as far as known. A Russian study on the mites says, "Demodex folliculorum shows signs of parasitism, while Demodex folliculorum brevis is a saprophyte." It is comparable to bacteria which humans have a relationship with, there is good bacteria and bad bacteria. The probiotic bacteria and the pathogen bacteria. The demodex mites usually pose no problem with the vast majority of humans since they are possibly on everyone. Why they become more numerous seems to be of more importance. For some unknown reason the mites are in higher density in rosacea patients. We don't know if the rosacea cause this increase in mites or does the increase in mites cause the rosacea, the old chicken or egg conundrum? There is evidence that reducing the mite density count improves rosacea. It is clear that the mites like human skin since they eat sebum. Maybe the increase of sugar/carbohydrate in the diet increases sebum which in turn increases the mite population, and voila, the inflammation of rosacea? I don't think all rosacea is demodectic. GUT Rosacea is a different variant, but may be connected or associated. The list of systemic comorbidities with rosacea keeps growing. The gut microbiome is obviously connected with skin microbiome (see my post on this).
  19. Earlier
  20. Related Articles Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study. J Dermatol. 2020 Mar 24;: Authors: Li J, Wang B, Deng Y, Shi W, Jian D, Liu F, Huang Y, Tang Y, Zhao Z, Huang X, Li J, Xie H Abstract Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2-22% in Europe and North America, prevalence in China is currently undetermined. We conducted a large population-based case-control study to determine the present epidemiological status of rosacea in China, involving 10 095 participants aged 0-100 years (mean age, 35.5 ± 19.1; 50.5% female). A census of rosacea among 15 communities in Changsha in south central China was conducted with skin examination by board-certified dermatologists. Rosacea was observed in 3.48% (95% confidence interval, 3.13-3.85%) of the study population. Subtype distribution was erythematotelangiectatic in 47.6%, papulopustular in 35.0% and phymatous in 17.4%. Family history was noted in 37.8% and ocular symptoms in 31.3%. Associations with rosacea were observed for melasma, hypertension, hyperthyroidism and breast cancer in females (P < 0.05), and also for hyperthyroidism and peptic ulcers in males (P < 0.05). Our results provide baseline information about epidemiological aspects of rosacea in China. PMID: 32207167 [PubMed - as supplied by publisher] {url} = URL to article
  21. Yes, because its all about immune system and HCQ does modulate the immune system in various ways and regulate the overactivity of immune system in some conditions. Not only does it work in getting rid of symptoms but it actually works behind the disease cause.
  22. The president announced on March 19, 2020 that hydroxychloroquine (Plaquenil) has been approved by the FDA to treat COVID-19. Virus has never been ruled out in rosacea. CNN has a followup report on this. There is a paper that indicates using Hydroxychloroquine (HCQ) to treat rosacea "exerted satisfactory therapeutic effects on erythema and inflammatory lesions of rosacea patients, indicating that it is a promising drug for rosacea in clinical treatment." Duff Man told us about this a while back that it worked for him. Wouldn't it be incredible if any rosaceans who are treated with hydroxycholoroquine for COVID-19 also discovered that their rosacea improves or clears up! Is virus involved in rosacea? If you do take hydroxycholoroquine and your rosacea improves, please let us know.
  23. Related Articles Rosacea is Characterized by a Profoundly Diminished Skin Barrier. J Invest Dermatol. 2020 Mar 18;: Authors: Medgyesi B, Dajnoki Z, Béke G, Gáspár K, Szabó IL, Janka EA, Póliska S, Hendrik Z, Méhes G, Törőcsik D, Bíró T, Kapitány A, Szegedi A Abstract Rosacea is a common, chronic inflammation of sebaceous gland-rich facial skin characterized by severe skin dryness, elevated pH, transepidermal water loss, and decreased hydration levels. Until now, there has been no thorough molecular analysis of permeability barrier alterations in the skin of rosacea patients. Thus, we aimed to investigate the barrier alterations in papulopustular rosacea (PPR) samples compared to healthy sebaceous gland-rich (SGR) skin, using RNASeq analysis (n=8). Pathway analyses by Cytoscape ClueGo revealed 15 significantly enriched pathways related to skin barrier formation. RT-PCR and immunohistochemistry were used to validate the pathway analyses. The results showed significant alterations in barrier components in PPR samples compared to SGR, including the cornified envelope and intercellular lipid lamellae formation, desmosome and tight junction organizations, barrier alarmins, and antimicrobial peptides. Moreover, the barrier damage in PPR was unexpectedly similar to atopic dermatitis (AD); this similarity was confirmed by immunofluorescent staining. In summary, besides the well-known dysregulation of immunological, vascular, and neurological functions, we demonstrated prominent permeability barrier alterations in PPR at the molecular level, which highlight the importance of barrier repair therapies for rosacea. PMID: 32199994 [PubMed - as supplied by publisher] {url} = URL to article
  24. "Webster et al. report a multicentre, randomized, double‐masked, parallel‐group, vehicle‐controlled study to evaluate the safety and efficacy of minocycline gel 1% and 3%. Topical minocycline had insignificant systemic absorption but produced significant reductions in mean inflammatory lesion counts with both the 1% and 3% concentrations. The response rate in the vehicle group was quite high, as is often the case in diseases with fluctuating inflammation. However, the 3% concentration of minocycline showed a significantly greater proportion of patients achieving Investigator's Global Assessment success at week 12 compared with vehicle. A topical minocycline foam formulation is in development, and this may provide a further useful option for treating papulopustular rosacea. How topical minocycline compares with other topical rosacea treatments is as yet unclear." Br J Dermatol. 2020 Mar 18;: Expanding treatment options for rosacea. Hampton PJ
  25. Related Articles Expanding treatment options for rosacea. Br J Dermatol. 2020 Mar 18;: Authors: Hampton PJ PMID: 32189331 [PubMed - as supplied by publisher] {url} = URL to article Full Text
  26. Related Articles Value of reflectance confocal microscopy for the monitoring of rosacea during treatment with topical ivermectin. J Dermatolog Treat. 2020 Mar 19;:1-9 Authors: Logger JGM, Peppelman M, van Erp PEJ, de Jong EMGJ, Nguyen KP, Driessen RJB Abstract Background: Reflectance confocal microscopy (RCM) enables noninvasive Demodex mite detection in rosacea. Objective scoring of rosacea severity is currently lacking.Objectives: To determine the value of RCM for monitoring Demodex, inflammation and vascular parameters in rosacea during treatment.Methods: In 20 rosacea patients, clinical and RCM examination were performed before, during, and 12 weeks after a 16-week treatment course with topical ivermectin. Using RCM, number of mites and inflammatory cells, epidermal thickness, and vascular density and diameter were measured. RCM features were correlated with clinical assessment.Results: Treatment resulted in clinical reduction of inflammatory lesions. Mites were detected in 80% of patients at baseline, 30% at week 16, and 63% at week 28. The number of mites reduced significantly during treatment, but no changes in inflammatory cells, epidermal thickness or vascular parameters were observed. Correlation between number of inflammatory lesions and mites was low. None of the RCM variables were significant predictors for clinical success.Conclusions: RCM enables anti-inflammatory effect monitoring of topical ivermectin by determining mite presence. Quantifying exact mite number, and inflammatory and vascular characteristics is challenging due to device limitations. In its current form, RCM seems of limited value for noninvasive follow-up of rosacea in clinical practice. PMID: 32189533 [PubMed - as supplied by publisher] {url} = URL to article
  27. The president announced today that hydroxychloroquine (Plaquenil) has been approved by the FDA to treat COVID-19. As mentioned in the initial post in this thread, virus has never been ruled out in rosacea. CNN has a followup report on this. There is a paper that indicates using Hydroxychloroquine (HCQ) to treat rosacea "exerted satisfactory therapeutic effects on erythema and inflammatory lesions of rosacea patients, indicating that it is a promising drug for rosacea in clinical treatment." Duff Man told us about this a while back that it worked for him. Wouldn't it be incredible if any rosaceans who are treated with hydroxycholoroquine for COVID-19 also discovered that their rosacea improves or clears up! Is virus involved in rosacea? If you do take hydroxycholoroquine and your rosacea improves, please let us know.
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  29. "In this case report, we detail the response of a 37-year-old Caucasian man with an overlap of erythematotelangiectatic rosacea and telangiectatic photoaging to brimonidine tartrate gel. With the application of brimonidine only on half of his face, skin analysis images, clinician's and patient's assessment showed that there was significant improvement in the erythema. This case has lent insight into how brimonidine can be used to assess the extent of photoaging by eliminating the erythema of rosacea to some degree. We propose that it can be used as a non-invasive test to differentiate between the two conditions, sparing patients from skin biopsies and molecular analysis." Australas J Dermatol. 2017 Feb;58(1):63-64. doi: 10.1111/ajd.12430. Epub 2016 Jan 13. Rosacea or photodamaged skin? Use of brimonidine gel in differentiating erythema in the two conditions. Oon HH, Lim ZV.
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