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Hypochlorous Acid

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"The formula of hypochlorous acid is HOCl. A chemist discovered hypochlorous acid in 1834. It is a primary compound of innate immunity. This acid is effective to use against a wide range of microorganisms." [1] 

"0.01% hypochlorous acid (HyClear™) was effective in disinfecting hybrid contact lenses and cases contaminated with bacteria, a yeast, and adenovirus." [2]

"HOCl has potent antimicrobial properties. Laboratory studies show that it effectively kills the nymph form of the Demodex mites, as well as the Bacillus oleronius and Staphylococcus aureus bacteria that live on eyelids and that are found inside the Demodexgut. In addition, HOCl also neutralizes the inflammatory toxins released by both mites and bacteria." [3]

"In a recent study, a saline hygiene solution preserved with pure hypochlorous acid was shown to reduce the bacterial load significantly without altering the diversity of bacterial species on the eyelids. After 20 minutes of treatment, there was >99% reduction of the Staphylococci bacteria" [4]

"In our study, hypochlorous acid, 0.01%, effectively eliminated all molds (including Fusarium and Aspergillus) and yeasts (Candida spp.) tested, with fungicidal activity observed in as little as 15 seconds. This rapid fungicidal and sporicidal activity is a significant advantage over traditional antifungal treatments that require hours or even days to show activity and may not be active against conidia (spores). Unlike some antifungal agents that are active against certain species but not others, hypochlorous acid showed rapid and potent activity against all species tested, including the genera Acremonium, Aspergillus, Fusarium, Mucor, and Candida. This broad spectrum of activity makes hypochlorous acid an attractive candidate for a global antifungal prophylaxis agent, especially in developing countries." [5]

HOCI is produced by our white blood cells, so our body recognizes it. At 200 ppm, HOCl is also listed by the FDA as Generally Recognized As Safe (GRAS), and is listed as being safe for use on food-contact surfaces by the USDA without the requirement of a rinse step. With HOCL there are no health risks with normal use, as evidenced by all zeros on safety data sheet. HOCL kills the Covid 19 virus. [6]


Clinical Reset by CelleRx is a pure hypochlorous acid, .01% as a preservative in saline. Alevicyn is another treatment. 

Amazon Hypochlorous Acid Treatments

Active Skin Repair Spray

Avenova Antimicrobial Eyelid and Lash Cleanser

Briotech Topical Skin Spray

BRIOTECH Topical Skin Spray 4 oz

CleanSmart Antimicrobial Skin Cleanser

Curativa Bay Hypochlorous Spray Mist

Defense Antimicrobial Skin Cleanser

Heyedrate Dry Eye Relief Kit

Heyedrate Hypochlorous Lid and Lash Cleanser

Ocusoft Hypochlor

OCuSOFT HypoChlor 0.02% Hypochlorous Acid Eyelid and Eyelash Gel

Puracyn Plus Wound and Skin Cleanser

SkinSmart Antimicrobial Clear Spray

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End Notes

HOCI image courtesy of Wikimedia Commons

[1] Does Hypochlorous Acid Eliminate Fungus?, Holistic Density, USA, Joe Doctora

[2] ARVO Annual Meeting Abstract  |   June 2020
The Disinfection of Bacterial, Fungal, and Viral Contaminated Contact Lenses and Cases with Hypochlorous Acid
Eric G Romanowski; Kathleen A Yates; John E Romanowski; Alex Mammen; Deepinder K Dhaliwal; Vishal Jhanji; Robert M Q Shanks; Regis P Kowalski

[3] New Approaches for Fighting Demodex Mites, Dr. Kathryn Najafi-Tagol, MD, Founder and Medical Director of the Eye Institute of Marin, New Medical Life Sciences

[4] Stroman, D. W; Mintun, K; Epstein, A. B; Brimer, C. M; Patel, C. R; Branch, J. D; Najafi-Tagol, K (2017).
"Reduction in bacterial load using hypochlorous acid hygiene solution on ocular skin".
Clinical Ophthalmology. 11: 707–714. doi:10.2147/OPTH.S132851. PMC 5402722. PMID 28458509.

[5] Cornea. 2015 Dec; 34(12): 1599–1605.
Fungal Infections Following Boston Type 1 Keratoprosthesis Implantation: Literature Review and In Vitro Antifungal Activity of Hypochlorous Acid
Silvia Odorcic, MD, FRCSC, Wolfgang Haas, PhD, Michael S. Gilmore, PhD, and Claes H. Dohlman, MD, PhD

[6] New Study Proves That Hypochlorous Acid Kills Novel Coronavirus, The Maritime Executive

Is hypochlorous acid key to reducing coronavirus risk?, Digital Journal


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