rss Posted March 24, 2015 Report Share Posted March 24, 2015 Assessment of rosacea severity: A review of evaluation methods used in clinical trials. J Am Acad Dermatol. 2015 Mar 19; Authors: Hopkinson D, Moradi Tuchayi S, Alinia H, Feldman SR Abstract BACKGROUND: Novel rosacea treatments are needed. Assessment methodologies for clinical trials of rosacea treatments are not standardized and are relatively inadequate. To determine the efficacy of new treatments, a valid and reliable assessment methodology is needed. OBJECTIVE: We sought to determine the assessment methodologies used in clinical trials for rosacea treatments, to demonstrate the need for a valid and reliable assessment tool, and to describe the relevant properties of such a tool. METHODS: PubMed and MEDLINE were searched for clinical trials of rosacea treatments since January 1, 1985. RESULTS: In all, 32 clinical trials met inclusion criteria. Assessment methodologies were highly variable, and standardized assessment methodologies were used in only 3 studies. The various manifestations of rosacea were assessed inconsistently. LIMITATIONS: Eighteen articles could not be included as a result of lack of access to the full text. CONCLUSIONS: The diverse methodologies make the assessment of novel treatments and comparison of treatments difficult. A valid and reliable assessment tool is needed to properly assess novel treatments to improve the management of rosacea.PMID: 25799418 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/pubmed/25799418?dopt=Abstract = URL to article Link to comment Share on other sites More sharing options...
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