Jump to content

PubMed RSS Feed - - Assessment of rosacea severity: A review of evaluation methods used in clinical trials.


Recommended Posts

Assessment of rosacea severity: A review of evaluation methods used in clinical trials.

J Am Acad Dermatol. 2015 Mar 19;

Authors: Hopkinson D, Moradi Tuchayi S, Alinia H, Feldman SR

BACKGROUND: Novel rosacea treatments are needed. Assessment methodologies for clinical trials of rosacea treatments are not standardized and are relatively inadequate. To determine the efficacy of new treatments, a valid and reliable assessment methodology is needed.
OBJECTIVE: We sought to determine the assessment methodologies used in clinical trials for rosacea treatments, to demonstrate the need for a valid and reliable assessment tool, and to describe the relevant properties of such a tool.
METHODS: PubMed and MEDLINE were searched for clinical trials of rosacea treatments since January 1, 1985.
RESULTS: In all, 32 clinical trials met inclusion criteria. Assessment methodologies were highly variable, and standardized assessment methodologies were used in only 3 studies. The various manifestations of rosacea were assessed inconsistently.
LIMITATIONS: Eighteen articles could not be included as a result of lack of access to the full text.
CONCLUSIONS: The diverse methodologies make the assessment of novel treatments and comparison of treatments difficult. A valid and reliable assessment tool is needed to properly assess novel treatments to improve the management of rosacea.

PMID: 25799418 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25799418?dopt=Abstract = URL to article

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Create New...