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"Low-dose isotretinoin was an effective therapeutic option for difficult-to-treat papulopustular rosacea."

A Randomized-Controlled Trial of Oral Low-Dose Isotretinoin for Difficult-To-Treat Papulopustular Rosacea
Presented in part at the Journées Dermatologiques de Paris Congress, Paris, 7–11 December 2010.
Emilie Sbidian, Éric Vicaut, Henri Chidiack, Elie Anselin, Bernard Cribier, Brigitte Dréno6, Olivier Chosidow

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"Very low-dose isotretinoin (e.g., 10–20 mg once to five times a week, equivalent to 5 mg/day) is an effective treatment for mild to moderate papulopustular rosacea and is well tolerated."

Australasian Journal of Dermatology, DOI: 10.1111/ajd.12522
Very low-dose isotretinoin in mild to moderate papulopustular rosacea; a retrospective review of 52 patients
Marius Rademaker, DM.

To Continue Reading About Low Dose Isotretinoin Click Here

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"Using isotretinoin for 1-2mg/kg/day for 3-4 months produces 60%-95% clearance of inflammatory lesions in patients with acne. Doses as low as 0.1mg/kg/day have also proven successful in the clearance of lesions. Encouraging results have also been seen in small numbers of patients with rosacea, Side effects affecting the mucocutaneous system and raised serum triglyceride levels occur in most patients receiving isotretinoin."

Profiles Drug Subst Excip Relat Methodol. 2020;45:119-157
Isotretinoin.
Khalil NY, Darwish IA, Al-Qahtani AA

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