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Isotretinoin

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Please post your comments on isotretinoin in this thread by clicking on the REPLY button. Low dose isotretinoin has been successfully used to treat recalcitrant cases of rosacea: 

"As previously discussed, isotretinoin is a viable alternative for recalcitrant cases of rosacea. In a large-scale, placebo-controlled, randomized, 12-week, multicenter study, Gollnick et al demonstrated complete remission in 24% and marked improvement in 57% of patients with isotretinoin 0.3 mg/kg therapy daily, in contrast with remission in 14% and marked improvement in 55% of patients treated with doxycycline 100 mg daily for 14 days, then 50 mg daily. Patients treated with isotretinoin rated treatment results at the end of the study as “excellent improvement” more frequently, at 32.6% in comparison with 24.2% for patients treated with doxycycline."

Clin Cosmet Investig Dermatol. 2015; 8: 159–177.
Published online 2015 Apr 7. doi: 10.2147/CCID.S58940
PMCID: PMC4396587 PMID: 25897253
Update on the management of rosacea
Allison P Weinkle, Vladyslava Doktor, and Jason Emer

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