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  1. Related Articles Demodex positive discoid lupus erythematosus: Is it a separate entity or an overlap syndrome? Dermatol Ther. 2020 Apr 10;:e13394 Authors: Dursun R, Durmaz K, Oltulu P, Ataseven A Abstract Discoid lupus erythematosus (DLE) is a chronic inflammatory erythematous skin disease that can be triggered by several factors. Rosacea is another skin disease that causes facial redness and tenderness. Demodex mites have been reported in rosacea and DLE patients commonly in the literature. These two diseases can be seen concomitant, mimic each o
  2. Related Articles Granulomatous rosacea-like skin rash: extranodal Rosai-Dorfman disease. Int J Clin Exp Pathol. 2020;13(3):556-558 Authors: Shen HP, Lu ZF, Zhu JW Abstract We report a 38-year-old man who presented with bilateral conjunctival congestion, hoarseness, and progressively growing pruritic, infiltrated skin lesions that had first begun over the face and neck, and later spread to the trunk and the limbs in 4 months. The clinical appearance of the lesions mimics granulomatous rosacea, acne vulgaris, or pityrosporum folliculitis. Histopatho
  3. Related Articles Efficacy of Topical Ivermectin for the Treatment of Cutaneous and Ocular Rosacea. Ocul Immunol Inflamm. 2020 Apr 07;:1-5 Authors: Sobolewska B, Doycheva D, Deuter CM, Schaller M, Zierhut M Abstract Purpose: To investigate the efficacy of once-daily topical treatment of ocular and cutaneous rosacea with ivermectin 1% cream (Soolantra®, Galderma).Methods: Ten patients with rosacea were evaluated in a retrospective monocentric pilot study. Subjective symptoms (measured with the Ocular Surface Disease Index), skin findings, and ocular
  4. Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania. Dermatology. 2020 Apr 06;:1-9 Authors: Lukaviciute L, Ganceviciene R, Navickas P, Navickas A, Grigaitiene J, Zouboulis CC Abstract BACKGROUND/OBJECTIVE: Skin diseases, especially those with visible manifestation, are considered to cause a major influence on global mental health. Therefore, we determined the prevalence and severity of anxiety, depression, and suicidal ideation in a large sample of p
  5. Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders. J Cosmet Dermatol. 2020 Apr 06;: Authors: Wiegmann D, Haddad L Abstract BACKGROUND: Many companies capitalized on treatable skin conditions by providing expensive prescription medications or high-end over-the-counter cosmetics. However, patients have become more apprehensive toward these medications in lieu of their often-detrimental side effect profile and reactivity with sensitive skin. AIMS: We developed a serum was created to co
  6. Related Articles The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders. Dermatol Online J. 2020 Feb 15;26(2): Authors: Saric-Bosanac S, Clark AK, Sivamani RK, Shi VY Abstract Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormon
  7. Related Articles [Recurrent chalazions in children]. Rev Prat. 2019 Oct;69(8):881-883 Authors: Doan S Abstract Recurrent chalazions in children. Chalazia are caused by an acute inflammation of sebaceous palpebral glands and lead to emergency consultation. Their treatment is most often medical, surgery is reserved for persistant forms. In case of multiple recurrent chalazia in a child, ametropia and ocular rosacea should be ruled out. The latter is a rare but potentially severe disease that can have blinding corneal complications. PMID: 32237654
  8. Related Articles Serum bilirubin and uric acid antioxidant levels in rosacea patients. J Cosmet Dermatol. 2020 Mar 31;: Authors: Turkmen D Abstract BACKGROUND: Rosacea is a common chronic inflammatory skin disease that the pathogenesis is not fully understood. Although the significant role of oxidative stress in rosacea pathophysiology has been shown in recent studies, there is no study addressing the potential roles of bilirubin and uric acid (UA) in rosacea. AIM: The purpose of this study was to assign serum bilirubin and UA antioxidant levels in rosacea patients.
  9. Related Articles Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study. J Dermatol. 2020 Mar 24;: Authors: Li J, Wang B, Deng Y, Shi W, Jian D, Liu F, Huang Y, Tang Y, Zhao Z, Huang X, Li J, Xie H Abstract Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2-22% in Europe and North America, prevalence in China is currently undetermined. We conducted a large population-based case-control study to determine the present epidemiological status of rosacea
  10. Related Articles Rosacea is Characterized by a Profoundly Diminished Skin Barrier. J Invest Dermatol. 2020 Mar 18;: Authors: Medgyesi B, Dajnoki Z, Béke G, Gáspár K, Szabó IL, Janka EA, Póliska S, Hendrik Z, Méhes G, Törőcsik D, Bíró T, Kapitány A, Szegedi A Abstract Rosacea is a common, chronic inflammation of sebaceous gland-rich facial skin characterized by severe skin dryness, elevated pH, transepidermal water loss, and decreased hydration levels. Until now, there has been no thorough molecular analysis of permeability barrier alterations in t
  11. Related Articles Value of reflectance confocal microscopy for the monitoring of rosacea during treatment with topical ivermectin. J Dermatolog Treat. 2020 Mar 19;:1-9 Authors: Logger JGM, Peppelman M, van Erp PEJ, de Jong EMGJ, Nguyen KP, Driessen RJB Abstract Background: Reflectance confocal microscopy (RCM) enables noninvasive Demodex mite detection in rosacea. Objective scoring of rosacea severity is currently lacking.Objectives: To determine the value of RCM for monitoring Demodex, inflammation and vascular parameters in rosacea during treatme
  12. Related Articles Expanding treatment options for rosacea. Br J Dermatol. 2020 Mar 18;: Authors: Hampton PJ PMID: 32189331 [PubMed - as supplied by publisher] {url} = URL to article Full Text
  13. Related Articles Identification of Long Noncoding RNA Associated ceRNA Networks in Rosacea. Biomed Res Int. 2020;2020:9705950 Authors: Wang L, Lu R, Wang Y, Wang X, Hao D, Wen X, Li Y, Zeng M, Jiang X Abstract Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide that adversely affects the health of patients and their quality of life. However, the molecular characterization of each rosacea subtype is still unclear. Furthermore, little is known about the role of long noncoding RNAs (lncRNAs) in the pathogenesis or
  14. Rosa canina image courtesy of Wikimedia Commons Related Articles Molecular mechanism of the anti-diabetic activity of an identified oligosaccharide from Rosa canina. Res Pharm Sci. 2020 Feb;15(1):36-47 Authors: Bahrami G, Miraghaee SS, Mohammadi B, Bahrami MT, Taheripak G, Keshavarzi S, Babaei A, Sajadimajd S, Hatami R Abstract Background and purpose: Because of the high prevalence, diabetes is considered a global health threat. Hence, the need for effective, cheap, and comfortable therapies are highly felt. In previous study, a novel oligosaccharide with
  15. image courtesy of Wikimedia Commons Related Articles Distinguishing rosacea from sensitive skin by reflectance confocal microscopy. Skin Res Technol. 2020 Mar 16;: Authors: Ma Y, Li L, Chen J, Chen T, Yuan C Abstract BACKGROUND: The updated standard classification and pathophys
  16. Related Articles Isotretinoin. Profiles Drug Subst Excip Relat Methodol. 2020;45:119-157 Authors: Khalil NY, Darwish IA, Al-Qahtani AA Abstract Isotretinoin is chemically named as: (2Z, 4E, 6E, 8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid. It is an orally active retinoic acid derivative for the treatment of severe refractory nodulocystic acne. It acts primarily by reducing sebaceous gland size and sebum production, and as a result alters skin surface lipid composition. Using isotretinoin for 1-2mg/kg/day for 3-4
  17. Related Articles Fatty acid profile and in vitro biological properties of two Rosacea species (Pyrus glabra and Pyrus syriaca), grown as wild in Iran. Food Sci Nutr. 2020 Feb;8(2):841-848 Authors: Hazrati S, Govahi M, Mollaei S Abstract The high demands for the consumption of edible oils have caused scientists to struggle in assessing wild plants as a new source of seed oils. Therefore, in this study, the oil yield, fatty acid and tocopherol compositions, antioxidant and antibacterial activities of the oils obtained from Iran's two endemic plants
  18. Related Articles [THE ROLE OF HELICOBACTER PYLORI IN ROSACEA AND PATHOGENETIC TREATMENT]. Georgian Med News. 2020 Jan;(298):109-112 Authors: Beridze L, Ebanoidze T, Katsitadze T, Korsantia N, Zosidze N, Grdzelidze N Abstract Rosacea is a chronic, recurrent skin disease. It may be aggravated by various factors. An increased incidence of rosacea has been reported in those who carry the stomach bacterium Helicobacter pylori. The purpose of this study was determination of the relationship of this infection with rosacea and to investigate effectiveness
  19. Related Articles Pulsed Dye Laser Alone Versus Its Combination With Topical Ivermectin 1% In Treatment of Rosacea: A Randomized Comparative Study. J Dermatolog Treat. 2020 Mar 06;:1-22 Authors: Osman MA, Shokeir HA, Hassan AM, Kahlifa MA Abstract Background While the aetiology of rosacea is multifactorial, it is not surprising that treatment has been controversial. Pulsed dye laser (PDL) has been successfully used to treat vascular components of rosacea. Ivermectin 1% cream is an emerging treatment of rosacea.Objective To provide a comprehensive c
  20. Related Articles Granulosis rubra nasi seen through the dermatoscope. JAAD Case Rep. 2020 Mar;6(3):234-236 Authors: Palit A, Sethy M, Nayak AK, Ayyanar P, Behera B PMID: 32140525 [PubMed] {url} = URL to article
  21. Related Articles Severe rosacea in a child. J Fr Ophtalmol. 2020 Mar 02;: Authors: Tijani M, Albaroudi N, Boutimzine N, Cherkaoui O PMID: 32139082 [PubMed - as supplied by publisher] {url} = URL to article
  22. Related Articles Skincare Habits and Rosacea in 3,439 Chinese Adolescents: A University-based Cross-sectional Study. Acta Derm Venereol. 2020 Mar 04;: Authors: Zuo Z, Wang B, Shen M, Xie H, Li J, Chen X, Zhang Y Abstract The pathogenesis of rosacea remains unclear but has been reported to correlate with skin barrier function. The objective of this study was to elucidate the skincare habits of Chinese adolescents and determine the relationship between skincare habits and rosacea. A university-based cross-sectional investigation included 310 rosacea
  23. Related Articles Thumbnail-squeezing method: an effective method for assessing Demodex density in rosacea. J Eur Acad Dermatol Venereol. 2020 Mar 03;: Authors: Huang HP, Hsu CK, Yu-Yun Lee J Abstract D. folliculorum, and D. brevis are human ectoparasites living in hair follicles and sebaceous glands of the skin, respectively, and most commonly on the face. They are normal flora, but D. folliculorum can cause disease when it proliferates excessively or penetrates the dermis. Increased densities of Demodex have been reported in rosacea-by reflectance confocal microscopy
  24. Related Articles Demodex folliculorum infestations in common facial dermatoses: acne vulgaris, rosacea, seborrheic dermatitis. An Bras Dermatol. 2020 Feb 12;: Authors: Aktaş Karabay E, Aksu Çerman A Abstract BACKGROUND: Demodex mites are found on the skin of many healthy individuals. Demodex mites in high densities are considered to play a pathogenic role. OBJECTIVE: To investigate the association between Demodex infestation and the three most common facial dermatoses: acne vulgaris, rosacea and seborrheic dermatitis. METHODS: Th
  25. Related Articles Conventional and Novel Treatment Modalities in Rosacea. Clin Cosmet Investig Dermatol. 2020;13:179-186 Authors: Engin B, Özkoca D, Kutlubay Z, Serdaroğlu S Abstract Rosacea is a common skin disease that is troublesome for both the patients and the dermatologists. Erythema, telengiectasia, papulopustular changes and phymatous changes are the main problems faced by the patients and dermatologists in everyday practice. Due to the chronic and relapsing nature of the disease, patients are usually unsatisfied with conventional treatment methods. This articl
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