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  1. Abstract In dermatology probiotic microorganisms have primarily been used orally for the prophylaxis and treatment of atopic disorders. In contrast to the successes achieved for gastrointestinal disorders, positive effects for atopic dermatitis only have been found in a few studies. New insights could now fundamentally change the impact of probiotics on dermatology. Probiotics are - like microflora of the skin - non-pathogenic microbes, which do not induce inflammatory responses in the skin. Common pathways for probiotics, non-pathogenic microbes, and microflora are characterized, in order to facilitate their more effective therapeutic use. These microbes display a majority of their effects directly at the site of application and thereby induce natural defense mechanisms. However, promotion of immunological tolerance is just as important in producing positive effects. Tolerance of the resident flora on surface organs developed during evolution and the mechanisms of action are multifaceted. Therefore, the topical application of probiotics and non-pathogenic microbes for prophylaxis and therapy of overwhelming cutaneous pro-inflammatory immune reactions is very promising. Results of recent clinical trials already have demonstrated the efficacy of this new therapeutic concept. Hautarzt. 2009 Oct;60(10):795-801. doi: 10.1007/s00105-009-1755-8. Outside-in. Probiotic topical agents. Volz T, Biedermann T.
  2. Abstract INTRODUCTION AND OBJECTIVE: Normal human skin can produce a range of antimicrobial chemicals that play an important part in eliminating potential cutaneous pathogens. Lactobacillus plantarum is a gram-positive bacteria that produces antimicrobial peptides, which when applied to the skin can act like an anti-inflammatory as well as enhance the antimicrobial properties of the skin. Clinical studies were conducted to determine the effect of lactobacillus extract on improvement of skin barrier and reduction of erythema from chemical irritant, skin microflora, and acne. Results show that lactobacillus extract was effective in reducing skin erythema, repairing skin barrier, and reducing skin microflora, thereby exhibiting an effective reduction in acne lesion size and erythema at 5%, but not at 1%. CONCLUSION: Based on the results of these studies, lactobacillus extract (5%) can be used to treat mild acne lesions. J Cosmet Sci. 2012 Nov-Dec;63(6):385-95. Physiological effect of a probiotic on skin. Muizzuddin N, Maher W, Sullivan M, Schnittger S, Mammone T.
  3. TEAE percentage rate is low with oxymetazoline treatment for rosacea. For more information.
  4. A new acronym, TEAE [Treatment-Emergent Adverse Events], has been published in the June issue of the Journal of the American Academy of Dermatology, in an article entitled, "Sustained Use of Oxymetazoline Cream Efficacious for Rosacea," according to MPR, about a study on the long-term safety (1 year) and efficacy of oxymetazoline cream 1.0% in 440 patients with rosacea spear headed by Zoe Diana Draelos, MD, who volunteers on the RRDi MAC. The study concluded: "This long-term study demonstrated sustained safety, tolerability, and efficacy of oxymetazoline for moderate-to-severe persistent erythema of rosacea." "The rate of discontinuation mostly due to application-site TEAEs was 3.2%" So the TEAE is low with oxymetazoline treatment for rosacea.
  5. Treatment for rosacea depends on the severity, but often requires some detective work to figure out your triggers as well as a carefully selected skin-care plan, including prescription and over-the-counter products. Some people may benefit from antibiotics, medications that specifically target redness, or isotretinoin (Accutane). For others, just keeping an eye on their triggers can have a profound impact. But the piece that tends to get overlooked in all of this is the mental health toll of dealing with a new skin condition—especially one that really has no cure. Below, we spoke with 11 people who have rosacea about how they were diagnosed, how they deal with their symptoms, and what they want others to know about the condition. 11 People Describe What It's Really Like to Have Rosacea, Sarah Jacoby, SELF
  6. "For instance, at 28, I had what I thought was stubborn acne for a few years. I went all out in the drugstore aisle with harsh, drying products that ended up doing more harm than good. So when I was finally diagnosed with rosacea this past December, I was actually relieved. I assumed that having an answer would make it easier to treat." Sarah Jacoby, Senior Health News Editor at SELF, who stated the above quote in her article, 11 People Describe What It's Really Like to Have Rosacea. SELF Masthead • Twitter • Muck Rack • Refinery29 • Linkedin
  7. image courtesy of Wikipedia Salvia hispanica, commonly known as chia, is a species of flowering plant in the mint family, Lamiaceae, native to central and southern Mexico and Guatemala. Wikipedia Comparing Essential Oils with Metronidazole and Mercury Oxide in Killing Mites (with emphasis upon Salvia Hispanic) Abstract Demodex belong to the smallest mites: the average length of adults is 250 μm. Up to now, two Demodex species have been described, which are specific for humans: Demodex folliculorum and Demodex brevis. A medical condition caused by presence of Demodexis called demodicosis. Gao et al. in 2005 reported good effects of tea tree oil on Demodex sp. in the in vitro and in vivo settings. Aim of this study was to check survivability of Demodex mites in various substances. Tests were made with the use of the most common substances used in demodicosis treatment, i.e. metronidazole and mercury oxide. The effects of essential oils from tea tree, sea buckthorn, aloe, salvia, peppermint, camphor tree, fennel, eucalyptus, and lavender were tested as well. For controls, Demodex were placed in saline. The mean survival time of Demodex was 64 hours for metronidazole, and 46 hours – for 2.5% mercury oxide. Much better results were obtained with 50% tea tree oil (7 minutes), peppermint oil (11 minutes) and salvia oil (7 minutes). Research Gate, December 2014 Effect of Metronidazol, Mercury Oxide and Essentials Oils on the in vitro survivability of Demodex mites. Aleksandra Sedzikowska,Maciej Oseka, B. Grytner-Zięcina, Emilia Jaremko ---------------------------------------------------------------- Abstract Demodicosis is a medical condition caused by presence of Demodex mites. Mites may cause ocular demodicosis with symptoms such as burning and itching of eyelids. Currently, several drugs are available for the treatment of demodicosis. However, their use carries a risk of serious side effects. According to recent studies, substances contained in some plant-derived essential oils kill Demodex mites. Good efficacy of tea tree oil against Demodex sp. has been reported. However, some patients develop allergic reactions and ocular irritation in the course of tea tree oil treatment. Tests with essential oils showed that salvia and peppermint oils rapidly kill Demodex-in 7 and 11 minutes, respectively. Salvia is known as a valuable herb and is used to treat eye disease. Therefore, salvia essential oil could be an alternative treatment for demodicosis. J Bacteriol Parasitol, 2015, Volume 6. Issue 3. Impact of Salvia and Peppermint Oil on the In Vitro Survival of Demodex Mites (PDF) Aleksandra Sędzikowska, Maciej Osęka , Beata Roman3and Emilia Jaremko. Department of General Biology and Parasitology, Medical University of Warsaw, Poland. Ofta Ltd., ul. Mleczna 8, 03-667 Warsaw, Poland, Verco Sp. z o.o., Warsaw, Poland.
  8. We learned about the Rositta Method in June 2012 at this thread at RF and it was a mystery how she treated rosacea patients for a long time. However, Conf posted [post no 109 11th May 2018 07:10 PM] an article published March 14, 2018 in Beauty Journaal (translated from Dutch) that describes her method of extracting demodex mite eggs and her complete treatment. You may watch this video below if you understand Dutch:
  9. What Dr. Kluk and I both thought interesting was your comment about rosacea. It’s very possible that you don’t have it, but as Dr Kluk told me: "Rosacea is very misunderstood as a condition, and it’s very common. If you google it, you’re going to get quite graphic photos of people with extreme redness, rough and broken skin, that sort of thing, but that is a very advanced kind of rosacea. There are much subtler, less pervasive forms of rosacea, and just because you have a less aggressive kind of rosacea now, it doesn’t mean it will become more like that at all. It’s possible to have rosacea without any textural changes to the skin." Dear Daniela: What Can I Do About My Red, Blotchy Skin? DANIELA MOROSINI, Refinery29
  10. Treating any specific skin issue is always about trial, error, and adaptation: What worked well one month might be fully ineffectual the next. But through all my experimentation — the countless serums, creams, toners, and treatments I’ve tried — these are the six essentials that consistently keep my skin calm all season long. 6 Beauty Essentials That Keep My Rosacea-Ridden Skin Under Control, Kelsey Haywood, Brit + CO
  11. According to Dr. Fishman, anyone with rosacea or especially sensitive skin would experience noticeable, positive differences with fewer products, fewer chemicals, and a decrease in skin irritants. "That includes exposure to cold, wind, low humidity, and extreme heat as well as products," she said. While it can be a bummer if you love product, she said, rosacea sufferers were not meant to constantly experiment with several new skin care formulations. "If you find products and ingredients that work for your skin, stick with them!" How To Navigate Beauty Products With Rosacea, by Lindsay Kellner, mbglifestyle
  12. The investigators concluded that the results of this study imply that the use of CD-doxycycline may have an impact on the previously reported association between rosacea and GID. This may be due in part to a dose-dependent effect, but it might also be linked to the inherent characteristics of the SD (modified-release) formulation of doxycycline. Longitudinal studies are warranted in order to further define this association. Fewer Gastrointestinal Issues in Rosacea Treated With Subantimicrobial vs Conventional Doxycycline, by Sheila Jacobs, Dermatology Advisor
  13. After my two weeks were up, my takeaway was pretty clear: Changing my diet helped clear up and prevent rosacea flare-ups, but it didn't eliminate them completely. I still had redness and new bumps pop up over the course of the two weeks, despite adhering to my "rosacea diet." To be fair, this type of diet probably produces best results over the long term, and I will continue to follow some of the recommendations because they were actually helpful. Can the "Rosacea Diet" Actually Clear Your Skin?, By Julia Malacoff, Shape
  14. A new photo series is rejecting a culture of ‘perfect’ pictures and airbrushing by celebrating women with common skin conditions such as acne, rosacea and eczema. Sophie Harris-Taylor’s project Epidermis is inspired by her own experience of being a young woman with severe acne, which left her struggling with self-confidence and acceptance. In Epidermis, twelve women are shown barefaced in unretouched images, some of who had never left the house before without their make-up on. Harris-Taylor says she deliberately shot it in the style of a beauty editorial shoot: “I wanted it to be seen as a beauty shoot first and an exploration of skin second.” With Epidermis, she hopes to make our perception of beauty less homogenised. Here, Harris-Taylor speaks to i about her series. This make-up free photo series is celebrating women with acne, rosacea and other skin condition, by Healther Saul, iNews
  15. The investigators concluded that the results of this study demonstrate the wide-ranging, negative impact of rosacea on self-perception: and emotional, social, overall well-being; rosacea-specific QoL. Effective treatments that address the underlying etiology of the disease and its troublesome symptoms — along with appropriate education — are necessary in order to achieve optimal aesthetic and psychosocial outcomes in individuals with rosacea. Rosacea Has Significant Effects on Emotional, Social Well-Being, by Sheila Jacobs, Dermatology Advisor