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  1. Logo of the Human Microbiome Project, a program of the NIH Common Fund, National Institutes of Health, image courtesy of Wikimedia Commons This subject of microbiome-based therapeutic strategies for rosacea is one of my favorite subjects which I have done a great deal of research on. You may want to read the latest article I have written on this subject of the human microbiome.
  2. Admin

    Three Gut Types

    They have now discovered that humans might be divided into three types of gut bacteria: Bacteroides, Prevotella and Ruminococcus, which may lead to personalizing medical treatment based upon which type gut microbes you predominantly have. "The three gut types can explain why the uptake of medicines and nutrients varies from person to person," [1] and may develop into a new ‘biological fingerprint’ on the same level as blood types and tissue types, akin to the 'blood type' diet and treatments. That is why probiotic treatment for rosacea is as valid, if not much better, as antibiotic treatment. Bacteroides Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. The DNA base composition is 40–48% GC. Unusual in bacterial organisms, Bacteroides membranes contain sphingolipids. They also contain meso-diaminopimelic acid in their peptidoglycan layer. Bacteroides species are normally mutualistic, making up the most substantial portion of the mammalian gastrointestinal microbiota, where they play a fundamental role in processing of complex molecules to simpler ones in the host intestine. As many as 1010–1011 cells per gram of human feces have been reported. They can use simple sugars when available; however, the main sources of energy for Bacteroides species in the gut are complex host-derived and plant glycans.[8] Studies indicate that long-term diet is strongly associated with the gut microbiome composition—those who eat plenty of protein and animal fats have predominantly Bacteroides bacteria, while for those who consume more carbohydrates the Prevotella species dominate.[2] Prevotella Prevotella is a genus of Gram-negative bacteria. Prevotella spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. These infections include aspiration pneumonia, lung abscess, pulmonary empyema, and chronic otitis media and sinusitis. They have been isolated from abscesses and burns in the vicinity of the mouth, bites, paronychia, urinary tract infection, brain abscesses, osteomyelitis, and bacteremia associated with upper respiratory tract infections. Prevotella spp. predominate in periodontal disease and periodontal abscesses. Research of human microbiota show that human gut is mainly inhabited by two phyla of bacteria – Firmicutes and Bacteroidetes, the latter mostly dominated by Bacteroides and Prevotella genera. Prevotella and Bacteroides are thought to have had a common ancestor. Formally, the two genera were differentiated in 1990. [3] Ruminococcus Ruminococcus is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the intestines of humans. The type species is R. flavefaciens. As usual, bacteria taxonomy is in flux, with Clostridia being paraphyletic, and some erroneous members of Ruminococcus being reassigned to a new genus Blautia on the basis of 16S rRNA gene sequences. [4] End Notes [1] What’s in your gut? Microbiota categories might help simplify personalized medicineBy Katherine Harmon | April 20, 2011Scientific American [2] Bacteroides, Wikipedia [3] Prevotella, Wikipedia [4] Ruminococcus, Wikipedia
  3. Caroline Jones, Rosacea Tips and Support Group, Facebook, reports, "I've been using egg white morning and night and my rosecea has completely gone after using for a month. I've suffered for over three years of red nose and cheeks with spots etc....Saw a programme about how they are looking at egg whites in medicine. It is full of collagen and helps get rid of wrinkles. So I tried it as anti wrinkle treatment.. Side effect was my rosecea started to get better....I just separate the white from the yolk and just smooth it as is over my skin. Leave for 10 mins ( your face will look like your young again whilst it tightens 😂) then just rinse with cold water. Pat dry. no whipping involved." If you try this treatment, please post in this thread your results.
  4. Dirk Bruere has a website where he has tried various formulas using DMSO with green tea, aspirin, alternating with a mixture of Copper Salicylate, Methyl Salicylate and Caffeine. He has tried other drugs/substances with DMSO which he lists that didn't work, and says he has totally cleared his rosacea for a good length of time. If you try this, please post your results in this thread.
  5. violentred26 at Reddit (scroll down to find her post) reports, "All I did was buy a big thing of 99% pure aloe Vera gel from Whole Foods (their brand) and a bottle of Jarrow Formulas Curcumin 95. I then opened one capsule of curcumin and dumped it into like two tablespoons of aloe (approximate, I didn’t measure). Then I spread the mixture all over my face and left on for 15 minutes. Oh, I also keep the aloe refrigerated so it’s nice and cold when I put it on. I did this mask once per day starting last Saturday through Tuesday, and I **** you not, it completely killed the rosacea flare up."
  6. Mastic Gum Tears - image Wikimedia Commons What is Mastic Gum? costcogoldmember at Reddit reports, "Took Mastic Gum for four weeks and HCL supplement (still to this day). This was the best my skin has ever looked in four years and it cleared up within a couple weeks. It's now March 2019 and I have clear skin." If you try this, please post in this thread your results. Jarrow Mastic Gum. Amazing Formulas Betaine HCL. Nutricost Betaine HCL Mastic Gum
  7. Wish I could help but don't really know. You may want to know about Jamie Kern Lima, IT Cosmetics, who a rosacea sufferer. Our affiliate store carries some of her line of products.
  8. Rebound according to Medicine.net is "The production of increased negative symptoms when the effect of a drug has passed or the patient no longer responds to the drug. If a drug produces a rebound effect, the condition it was used to treat may come back even stronger when the drug is discontinued or loses effectiveness." This can happen with any drug, but with rosacea the reports of rebound most often are with Mirvaso (Brimonidine) and to a lesser extent with Rhofade (Oxymetazoline Hydrochloride). The RRDi began collecting anecdotal reports of Mirvaso Rebound and stopped at 242. Both of these drugs are vasoconstrictors. You should be aware of this side effect or risk associated with these two drugs.
  9. The Daily Mail reports of an ex-model, Rebecca Morrison, who was able to stop her antibiotic treatment she was using for her rosacea and successfully used Kalme Day Defence SPF 25. Rebecca is reported to say, "I've now been using Kalme for a year and have been more or less free from all the symptoms for the majority of that time. Since using product I've seen almost 100 per cent improvement in my skin. I still get a few pimples now and then when I'm especially stressed and get a little flush if I'm out in the sun but zero flaking skin, painful irritation or furious redness! It has truly changed my life!" Kalme Day Defence SPF 25 is sold in the United Kingdom and you can review the ingredients. Mother whose rosacea left her skin a 'furious' mess during pregnancy reveals she improved her skin in just four weeks WITHOUT medication - and it was all thanks to a £19.95 cream, By Chloe Morgan for MailOnline, Daily Mail
  10. Keep us posted on your progress. Taking probiotics (there is a lot of discussion on what brand to buy, but I think the main thing is your taking some kind of probiotic) along with Efracea can only help your gut and skin. I personally take bunch of vitamins and minerals. If you are interested in this subject, read this article on this FAQ: Do Rosacea Sufferers have Nutritional Deficiencies?
  11. Hi Jesse, Thanks for joining the RRDi and posting. The Efracea (European version of Oracea) and Soolantra are the gold standard for rosacea treatment currently, the state of the art. It has been reported that using Soolantra it does get worse before it gets better, but some report no worsening of the skin, only improvement. The Efracea should improve your skin since you responded so well with doxycycline before. You may want to look into probiotic treatment since this is now a medically acceptable treatment for rosacea. After you skin improves, you may want to consider the long term effects of antibiotic treatment and opt out for probiotics. There are many who report successful treatment of the gut, which the RRDi recognizes as GUT Rosacea when rosacea responds to intestinal treatment. Not all rosacea is demodectic rosacea and the RRDi is the only non profit for rosacea that recognizes thirteen variants of rosacea. Since you have dry skin you may want to consider the new cosmetic ZZ cream which will be released in April 2019 and is designed for dry skin manufactured in China by the Zhongzhou Pharmaceutical Company, the company that manufactures the original famous ZZ Cream. The Cosmetic ZZ cream has already been released in Europe as Demoderm. You may respond well to it so it may be worth your effort to try it since you are so close to the source. You will know in thirty days whether the ZZ cream works for you. Since you live in Hong Kong you may find is easy to drop by Demodex Solutions, a sponsor of the RRDi, at this address: Demodex Solutions limited 1450 Chun Shing Factory Estate 85-89 Kwai Fuk Road Kwai Chung NT Hong Kong Tel: (852) 81916262 Mobile: (852) 85267369688 Fax: (852) 67369688 Email: info@demodex.com Skype name: demodexsolutions
  12. image courtesy of Wikipedia Over the years it has amazed me how the public has so little knowledge of the three basic food groups, i.e., protein, fat and carbohydrate. Yes, a significant number of the public can name the three basic food groups, but that is as far as it goes and where the confusion begins. The public receives a lot of nutrition recommendations by not only their teachers, physicians, and the government, but also the incredible amount of data on the internet which appears to further confuse everyone. For example, the USDA Center for Nutrition Policy and Promotion lists five food groups in the MyPlate program, while the National Institute of Health proposes the Dietary Approaches to Stop Hypertension (DASH) diet lists eight food groups, and Pass My Exams lists seven nutrition food groups. If you google this subject, you will get so many different recommendations on what constitutes the food groups and how many there should be. Nutrition Facts Label However, in most countries in the world, there is now mandated a Nutrition Facts Label that is prominently displayed on food and drink products that can really clear up all this confusion. In the USA, the "label was mandated for most food products under the provisions of the 1990 Nutrition Labeling and Education Act (NLEA), per the recommendations of the U.S. Food and Drug Administration." [1] Technically, the Pass My Exams that lists the seven nutrition food groups is closer to what is required for proper nutrition [2], and is true to survive and live healthy one needs all seven food groups listed but technically, carbohydrate is not an essential nutrient since you can obtain glucose, which is an essential carbohydrate nutrient required to survive that can be obtained from protein or fat. [3] Nevertheless, most humans obtain glucose from consuming carbohydrate and you do need the other six food groups and the Nutrition Facts Label can help sort through the confusion. For example, in the image at the top of this post is an example of the Nutrition Facts Label on a package of macaroni and cheese. The three basic food groups are in bold letters, Fat, Carbohydrate and Protein. Depending on the food or drink item the label may also include other nutrients such as Vitamins or minerals. However, if you note, water is never mentioned as a nutrition since everyone usually knows that water is essential for human survival and to maintain a healthy status, even though most food and drink contains some water. In this example, macaroni and cheese contains mostly carbohydrate (31 gram), fat (12 grams) and protein (5 grams) making a total of 48 grams. If you look at the total serving in this example it is 228 grams. If you subtract the basic three food groups from the total serving size you have 180 grams. So how do you account for the 180 grams? The Nutrition Facts Label acknowledges some of the essential nutrients such as sodium which amounts to 470 mg (less than half a gram). The other essential nutrients listed such as Vitamin A, Vitamin C, Calcium and Iron only take up such a trace amount of milligrams that it is not even listed. Water takes up most of the 180 grams unaccounted for. The label gives you information at the bottom concerning 'daily values' that is supposed to be helpful but can also be very confusing to the average reader, which if you want to clear up this confusion, you will have to do some more research. What is the most helpful information about the Nutrition Facts Label is that it lists the three basic food groups, protein, fat and carbohydrate. You can determine the amount or the percentage of each of these food groups. To determine the percentage is simple math. Take our example of macaroni and cheese which contains a total of 48 grams. To determine the percentage of carbohydrate contained in this food serving you simply divide 31 grams into 48 grams and the result is 64.5% which is the total percentage of carbohydrate in a 228 gram serving of this item. This is why the label is so helpful, you can determine what the primary amount or percentage of a food or drink in terms of the three basic food groups. This helps you know how to see what you are consuming each day in terms of these basic three food groups. Food Groups, Body Mass and Rosacea For rosaceans who are concerned about diet triggers, particularly sugar and carbohydrate diet triggers, understanding that the human body is mostly made up of water, protein and fat and how little is comprised of carbohydrate (about 1%) [4], should clear up some of the confusion on how over consuming carbohydrate can be an issue for rosacea sufferers. Using the Nutrition Facts Label to gain proper data on what you are consuming will help you see how your high carbohydrate diet is a factor in triggering your rosacea. [5] You can then decide what you want to do about this using the information you just read. End Notes [1] Nutrition facts label, Wikipedia [2] The seven essential nutrients are the following: Carbohydrate Protein Fat Fibre Vitamins Mineral Water Source: Why We Need Food, Pass My Exams [3] Carbohydrate Not Essential For Human Survival [4] Carbohydrate Body Mass Percentage [5] Sugar and Rosacea
  13. Many rosaceans complain of dry skin issues and want to find the perfect moisturizer. Those with oily skin usually don't complain about this issue. However, if you are treating your rosacea with sulphur based treatments, finding a perfect moisturizer can really be hard to find. You may want to ask your dermatologist for sample to try either the original formula emollient cream or the low sulphur emollient. This may be what the doctor ordered for your dry skin issues. AVAR-e® Emollient Cream Prescribing Information AVAR-e® LS Emollient Cream Prescribing Information
  14. My dermatologist gave me some samples of Avar-e Green and I noticed that it does indeed help my rosacea and SD. You may want to ask your dermatologist for some samples to try out and see if it works for you. Please post in this thread your results. AVAR-e Green® Cream Prescribing Information
  15. image courtesy of Wikimedia Commons “The body of a healthy lean man is composed of roughly 62 percent water, 16 percent fat, 16 percent protein, 6 percent minerals, and less than 1 percent carbohydrate, along with very small amounts of vitamins and other miscellaneous substances. Females usually carry more fat (about 22 percent in a healthy lean woman) and slightly less of the other components than do males of comparable weight.” Human Nutrition, Kenneth Carpenter A. Stewart Truswell Douglas W. Kent-Jones Jean Weininger, Encyclopedia Britannica So depending on the weight and sex, you can see that the majority of the human body is water (62%), and protein and fat make up about a 50/50 ratio comprising of about a third of the body mass, while carbohydrate only amounts to a tiny 1% of the body mass. Since there is so little carbohydrate making up your body mass, why is it that today's modern diet consists of more carbohydrate than protein and fat? Yet, for most humans living in the modern world, the diet consists of a majority of carbohydrate. In times past, say a couple of hundred years ago, humans ate more protein and fat, or at the very least equal amounts of all three food groups. The increase of carbohydrate in the human diet, particularly sugar, whether as high fructose corn syrup or sucrose (or any other sugar) has only happened in the last couple of hundred years, particularly in the last one hundred years. What has the increased sugar intake in human consumption along with other carbohydrate done to health? The increased knowledge data of over consumption of sugar/carbohydrate continues to show the detrimental effect to human health and you are without a doubt aware you should limit your sugar/carbohydrate intake to improve your health. You know you are consuming too much sugar/carbohydrate in your diet and this is triggering your rosacea. If you are not convinced, why not try reducing sugar/carbohydrate for thirty days and see if your rosacea improves? This will probably be the hardest fast you have ever done since sugar/carbohydrate is embedded into the typical modern industrial diet and it is so difficult to avoid sugar/carbohydrate, mainly because you are addicted to sugar. But a clear face is worth it, isn’t it?
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