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  1. Thanks Apurva, and also thanks for your article on co-existence.
  2. Hi Apurva, I was reluctant to download a docx file since it is an odd way of posting instead of simply copying and pasting your document into the post? I checked to see if your file contained any viruses or malware by using VirusTotal and it passed, so I opened the file and I am copying and pasting your article here for the benefit of everyone else not having to go through this process. It might be best to simply write your posts. Here is the contents of your article below: begin article___________ Co-existence of Rosacea, Seborrheic dermatitis and Blepharitis There have been a lot of reports on accounting other chronic skin conditions with rosacea and it is true that you can have multiple conditions simultaneously with rosacea. I have experienced rosacea, seborrheic dermatitis and blepharitis together with the combination of erythema and telangiectasia. The very first time this condition appeared as a lesion on half part of nose and cheek and then covered the other part of the face with having scaly torn skin and inflamed eyes. After years of my experience and dealing with these conditions, the symptoms include : Swollen flushed skin, visible dilated blood vessels with stinging and burning sensation on face. SD can cause skin scaly and flaky and can burn with itch and appears mostly on front hair line,forehead and eyebrows that if you itch the flaky and crusty skin falls off like dandruff. Blepharitis usually involves upper eyelid and causes inflamed eyelids, teary red eyes and the most important visual aspect is greasy dandruff like scales form on eyelashes covering half of it. The conditions can go beyond your cheeks and nose and affect earlobes and chin area and can cause flaky and rough chin area with small bumps. The flare ups can last anywhere from few minutes to one day or to one month and they again come back but when it goes you can feel the temperature decrease but it can leave red bumps that looks like acne but gradually the red appearance goes with time but it waxes and wanes. Co-existence : The occurrence of other chronic inflammatory diseases like seborrheic dermatitis and blepharitis are common in patients with rosacea and the good news is, the treatment of other condition does not aggravate the signs and symptoms of rosacea and lessen the flare ups in the meantime. Blepharitis is an inflammation of the eyelids in which the base of the eyelids are swollen and red and flaky greasy like crusts occur around the eyelashes with frequently mildly sticking eyelids and flaky dandruff of eyebrows sometimes called seborrheic blepharitis.(1) It is reported that demodex can worsen the condition of rosacea but it can also aggravate the condition of seborrheic blepharitis.(2) SD can typically occur as rash on the face and a sheet of lesion on back and middle chest area and middle and underneath breast lines. The underlying cause of seborrhoeic dermatitis is not clear, but a type of yeast called Malassezia furfur is involved.(3) I will emphasize these conditions thoroughly in later posts but for now I will explain the treatment I had with these three conditions : When my doctors diagnosed these three conditions, first they prescribed me low dose oral doxycycline capsules (100mg) daily at night. 1. Doxycycline is an antibiotic used for treating bacterial infections.The drug is also sold under the brand names Oracea, Doryx, Monodox, Periostat, and Vibramycin. Doxycycline is in a class of medications called tetracyclines, and it's a broad-spectrum antibiotic, it works against a wide range of bacteria.This medication is used to prevent malaria and treat a wide range of infections, including: skin infection.(4,5) Side effects: stomach upset, constipation, nausea, heavy head. 2. You can apply topical metronidazole gel 0.75% on the affected skin area. Apply a thin layer of gel once or twice daily.I used to apply once at night daily. It is an antibiotic and it works by decreasing redness and inflammation by stopping the growth of certain bacteria and parasites.This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections. (6) Side effects : burning and eye irritation if it gets close to the eyes. 3. Ketoconazole 2 % and Zinc pyrithione 1 % (Shampoo) for the fungal and yeast infections of the skin. Ketoconazole an active ingredient works by interfering and weakening with the formation of the fungal cell membrane. It better works with seborrheic dermatitis and blepharitis. Thoroughly apply on wet hair and massage and leave it for 5 minutes and then rinse it out. It does not make lather like other shampoos. Take a drop on finger, rub it and apply gently on eyelashes on tightly closed eyes and rinse it properly. With 8 weeks of proper use twice in a week completely cured me with SD and blepharitis. Side effects : itchy and dry scalp 4. If you have dermatitis on your chest and breast lines and back, you can use the composition of Boric acid and Clotrimazole cream together. It works by reducing inflammation and inhibiting the growth of fungi. Apply a thin layer of this base and rub until it absorbs completely twice or thrice daily. I applied this on my front and back area for four to five days and it worked wonder and the lesions gradually disappeared. Note : before taking any above medication consult your doctor or physician and alcohol should not be consumed during any medication it can worsen the condition of rosacea and if you are pregnant or on breast-feeding and any other condition like diabetes or heart problem, take this medications as directed by your doctor. Instead relying on oral and topical steroids my doctor prescribed me with bacterial and fungal medications because taking steroids for SD and blepharitis can exacerbate the condition of rosacea and relying on antibiotics and anti-fungal treatments can lessen the condition of SD and blepharitis and keep the rosacea at bay. References : https://www.aoa.org/patients-and-public/eye-and-vision-problems/glossary-of-eye-and-vision-conditions/blepharitis.(1) http://eyewiki.aao.org/Blepharitis.(2) http://www.londoneyeunit.co.uk/services/blepharitis/.(3) https://www.everydayhealth.com/drugs/doxycycline.(4) https://www.webmd.com/drugs/2/drug-8648-7073/doxycycline-hyclate-oral/doxycycline-oral/details.(5) https://www.webmd.com/drugs/2/drug-6426/metro end article_________________
  3. Admin

    Treatments for Demodex Skin Mites

    Thanks so much for your post, very detailed and informative and without a doubt will help many.
  4. Leo Pharma has announced it is purchasing Finacea, as well as other dermatological treatments from Bayer according to this news release.
  5. Nasdaq reports "Aclaris Therapeutics to Acquire Worldwide Rights to RHOFADE® from Allergan." Aclaris originally owned Rhofade and sold it to Allergan and is now buying it back.
  6. Admin

    ZOSSO, aka ZZ Cream

    Besides still taking the Lutein/Zeazanthin treatment, I use the ZZ cream about four or five nights a week on some red spots, however, in addition, before I do apply the ZZ cream, I have been applying a small amount (half teaspoon) of 3% hydrogen peroxide from Walmart (57 cents a bottle) to some red spots and let this dry before applying the ZZ cream. I have noticed when applying the 3% hydrogen peroxide it doesn't sting but after it dries and deeply penetrates the skin I get some stinging which is odd to me but indicates it is finding something down deeper in my skin to work on. The results have been good so I am updating my photos below today:
  7. Admin

    Rosacea: Beyond the visible

    smart2005ct, That is such good news you are seeing Percy Lehmann, MD, who volunteers on the RRDi MAC. Keep us posted on your progress.
  8. Galderma has released a report, Rosacea: Beyond the visible, which is an "An open letter to doctors treating rosacea," answering seven questions proposed about treating rosacea. Galderma sponsored a 'global survey of rosacea burden' of 710 rosaceans and 554 doctors which is used as data for the report with the stated goal of achieving total clearance (IGA 0). The report acknowledges, "Although we can’t yet promise ‘clear’ to all people, current treatments are now getting more people to ‘clear’, with combined therapy or even with monotherapy. By aiming for ‘clear’ (IGA 0) we can help free more people from their rosacea burden." One statement that explains rosacea best in the report is, "Ultimately, rosacea is a subjective and entirely individual experience." While we try to categorize rosacea into phenotypes and treatment protocols, there is no one treatment that works for everyone.
  9. Bloomberg reports, "Nestle said Thursday it would consider new owners for its dermatological business, a unit with $2.8 billion in annual revenue that Chief Executive Officer Mark Schneider said may no longer fit with the company’s overall strategy of focusing on products such as coffee, water and pet food." [1] Nestle owns Galderma, which is part of its 'dermatological business' or 'Nestlé Skin Health.' As David Pascoe puts it, "Lets hope that a pharma with deep pockets emerges, one that sees value in the assets of Galderma and further sees a future in developing new treatments that help rosacea sufferers." [2] Rosacea sufferers usually are very much aware of Galderma's Soolantra, Oracea, Mirvaso and Metrogel (Metrocream). We shall wait and see what happens. End Notes [1] Nestle's Step Away From Skin Health Reignites L'Oreal Sale Talk By Thomas Mulier and Corinne Gretler, Bloomberg [2] Galderma for sale – why we need the right buyer, by David Pascoe, Rosacea Support Group
  10. Full Text The four components of this treatment are: (1) Dextran sulfate is an anionic polymer of sulfated glucose [1] Dextran sulfate contains approximately 17% sulfur which is equivalent to approximately 2.3 sulfate groups per glucosyl residue. [2] (2) 4-t-butylcyclohexanol [BCH; TRP-regulin ®] [3] (3) pongamia oil [4] (4) hesperidin methyl chalcone [HMC] [5] Some of the products mentioned in the above post, "Avène redness-relief cosmetic products for sensitive skin prone to redness" are: Eau Thermale Avène Antirougeurs Clean Redness-Relief Refreshing Cleansing Lotion Eau Thermale Avène Tolérance Extrême Emulsion Eau Thermale Avène Antirougeurs Calm Soothing Repair Mask Eau Thermale Avène Xeracalm A.D Lipid-Replenishing Cleansing Oil Eau Thermale Avène Skin Recovery Cream Eau Thermale Avène Cicalfate Restorative Skin Cream Eau Thermale Avène Extremely Gentle Cleanser Lotion Eau Thermale Avène Antirougeurs Dermo Cleansing Milk Eau Thermale Avène Antirougeurs Day Redness Relief Soothing SPF 25 Cream Eau Thermale Avène Antirougeurs Fort Relief Concentrate End Notes [1] Dextran Sulfate, Sodium Salt (CAS 9011-18-1), Santa Cruz Biotechnology [2] Dextran Sulfate, Sigma Aldrich, Millipore Sigma [3] PubChem, Sigma Aldrich, ChemSpider, Paula's Choice, Safety Data Sheet, Effective treatment for sensitive skin: 4-t-butylcyclohexanol and licochalcone A [4] derived from the seeds of the Millettia pinnata tree [5] Paula's Choice, Truth in Aging, Douglas Laboratories,
  11. Admin

    Candida Albicans And Rosacea

    One paper links Fungal keratitis associated with ocular rosacea
  12. ElaineA [post no 3] reports trying this treatment and posts on September 14, 2018, "I am still clear at 7 months post oral treatment."
  13. Admin

    Is Coffee A Rosacea Trigger?

    Thanks Vestpocket for your post on this subject and pointing out how tiny the population of only 24 people in the study was. Wouldn't it be a novel idea for a group of rosaceans to get together and fund their own research. For example, let's get 10,000 rosacea sufferers together in a non profit organization dedicated to find the cure for rosacea and each rosacean donates $1 to this non profit organization who when funds a rosacea double blind, placebo controlled, clinical study on a rosacea trigger, such as coffee, or for that matter, whatever the 10,000 rosacea sufferers deemed to be a clinical subject worth investigating. Certainly one of the RRDi MAC members might be interested in receiving $10,000 to conduct such a clinical study that rosaceans would like to fund rather than the current status quo studies being done now by the other two non profit rosacea organizations. As mentioned in the initial post, there is a difference between a flushing trigger and a rosacea flareup trigger. When you drink coffee (or for that matter ingest caffeine from green tea or whatever) after you flush, and eventually recover from the flush, does the flush exacerbate your rosacea seriously, or after the flush subsides, is your rosacea unchanged?
  14. Let's review what the good points of having a non profit organization for rosacea founded by rosacea sufferers for patient advocacy vs the other two non profits for rosacea founded by non rosacea sufferers (NRS, and the AARS). (1) The purpose of this non profit obviously isn't for personal profit since everyone who has had anything to do with the RRDi hasn't done it for money. All Volunteers. Compare that with the other two non profit organizations for rosacea (NRS, and the AARS) and follow the money. (2) There is a wealth of rosacea treatment data in the member forum in logical categories. The search feature can help you find what you are looking for. (3) Education grants. (3) The RRDi MAC is one of the Crown Jewels, since these medical and research professionals have some interest in rosacea and have graciously volunteered to have their name listed on our website and have agreed to answer questions and help guide the RRDi. (4) The affiliate shopping cart is an incredible source of over the counter treatments and publications related to treatment not only for rosacea, but also other skin conditions. You can review what research the NRS and the AARS have engaged in, and decide if you think these two non profit organizations funding for research is the way it should be done. Or if you think there should be improvement into what rosacea research needs to be done, think about this option: Reaching the goal of 10,000 rosacea sufferers becoming members of the RRDi. Each member contributes one dollar a year. The RRDi could sponsor their own unique rosacea research that rosacea sufferers want done and fund it themselves. Can you do that with the other two non profit organizations for rosacea? So think about all this and volunteer! Join the RRDi. Contact admin and let us know you want to volunteer.
  15. Admin

    Baby You Can Drive My Gut

    "SCFA (short-chain fatty acids) molecules are a subset of fatty acids that are churned out by some types of gut microbes during the fermentation of fiber. They're associated with maintaining gut health and protecting against disease....And experiments recently showed that certain types of bacteria extracted from baby feces could promote the production of short-chain fatty acids (SCFA) in mice, and in a medium simulating the human gut...."Short-chain fatty acids are a key component of good gut health," lead study author Hariom Yadav, an assistant professor of molecular medicine at Wake Forest School of Medicine, said in a statement....Fecal microbiota transplants (FMT), or "poop transplants," can treat a type of gut disorder with an infusion of diverse bacteria from a healthy digestive system, distilled from a donor's poop. This helps to correct imbalances of microbial diversity when the gut microbiome is dominated by the bacteria Clostridium difficile (C. diff), which can lead to serious gut disorders." "Previous studies have investigated the use of probiotics — those healthy gut bacteria — by testing their impact in guts already affected by disease, the researchers wrote in the study. For the new investigation, they wanted to see how a probiotic would impact SCFA production in a healthy gut. They chose to work with baby poop because infants' gut microbiomes are typically free from age-related diseases "such as diabetes and cancer," and because of the sheer abundance of infant feces at their disposal. ("Their poop is readily available," Yadav said.)" Will Baby Poop Bacteria Become the New Probiotic? By Mindy Weisberger, Senior Writer, Live Science "While the new study examined what happened to mice after they received the mixture — there hasn’t been a study on humans yet — Yadav says that 'we are also planning to put these probiotics in yogurt, kombucha, and several other mediums for human use.' ” Why Scientists Think Baby Poop Is a Medical Gold Mine Probiotics are the future, baby. By Sarah Sloat, Inverse
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