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Admin

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  1. According to PRNewswire, New York, dated December 5, 2018, 'rosacea therapeutics demand to exceed $2 billion dollars.' This report includes an interesting factoid that "In the consolidated competitive landscape of rosacea therapeutics market, four leading companies account for over 75% share of the total market value, including Pfizer Inc., Teva Pharmaceutical Industries Ltd., Foamix Pharmaceuticals Ltd., and Bayer A." Rosacea Therapeutics Demand to Exceed US$ 2 Billion in 2019 - Persistence Market Research, PRNewswire, 12/5/2018
  2. "Today, Aug. 21, 2019, a Delaware court issued an opinion finding three key patents covering Galderma’s Soolantra acne cream invalid and not infringed by Teva’s generic product....The FDA granted tentative approval to Teva’s generic product in March of this year; because of today’s decision, the FDA is now permitted to grant final approval. Today’s opinion is favorable for Teva, which may now launch its generic product at risk once it receives final approval from the FDA." (TEVA) Soolantra: Delaware Court Finds Galderma Patents Invalid; Teva May Launch Generic Version of Soolantra At Risk
  3. This is a note from the RRDi Treasurer about grant writing basics. Please read this page first! The RRDi received some education grants from Galderma which you can review here: https://irosacea.org/articles/rrdi-education-grants/ Grant writing is a tedious and arduous task and we appreciate your volunteering to help us. We went through all sorts of hoops with Galderma to get those grants. Now the process has changed and we are still trying to figure it out. What each company requires is different and you have to go through hoops to learn. Basically, it would be prud
  4. "It was detected that number of Demodex affected from the glucose level and each increase in glucose level cause an increase on Demodex as 0.190 (P = .00, t = 4.746, B = 0.190, r = 0.57, Durbin-Watson = 1.801, confidence interval = 0.110 to 0.271 (for glucose))." J Cosmet Dermatol. 2020 Oct 05;: Association between Demodex folliculorum and Metabolic Syndrome. Toka Özer T, Akyürek Ö, Durmaz S Demodex Density Count - What are the Numbers? Sugar and Rosacea
  5. You can make a difference while you shop Amazon Prime Day deals on October 13 & 14. Simply shop at smile.amazon.com/ch/20-1259275 or with AmazonSmile ON in the Amazon Shopping app and AmazonSmile donates to Rosacea Research And Development Institute.
  6. Now available announced by Vyne Therapeutics. Ask your dermatologist. Post your experience in this thread. Find the reply button. "The Company also announced that the annual list price of ZILXI will be $485 per 30-gram canister, in parity with the wholesale price of AMZEEQ® (minocycline) topical foam, 4%, the Company's topical minocycline indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in adults and pediatric patients 9 years of age and older." PR Newswire Association LLC. All Rights Reserved. A Cision company
  7. Admin

    Brady's Blog

    Went to my dermatologist appointment yesterday and Dr. Harper feels that her regimen is improving my rosacea/SD/folliculitis and I concur. She says to keep taking the 20 mg tab oral doxycycline twice a day and gave me more generic 15% azelaic acid gel prescriptions and scheduled an appointment for my next visit February 1, 2021. The Finacea she offered to refill more prescriptions but my insurance co-payment is $57 and even though I think the 15% Finacea Foam is probably better than the generic 15% gel, I don't think it is that much better so I opted NO on the Finacea, which is for those who h
  8. Molecular functional analysis circulating RNA of patients presented as effective to ISO therapy image courtesy of PubMed Central. "In conclusion, we found that isotretinoin could temporarily alter gene expression in acne patients, and the gene profiles among oral ISO-induced acne flare-up, effective, and ineffective patients were distinct. ISO therapeutic mechanisms were not only involved in regulating the inflammatory reaction but also in the process of DNA repair. Genes that regulated the inflammatory and defense response to microorganisms played a role in ISO treatment effects. GATA2,
  9. "Overall, the current study demonstrates that topical minocycline gel is safe, efficacious and well tolerated in patients with papulopustular rosacea. The findings of this study support further evaluation of topical minocycline gel for the treatment of papulopustular rosacea." Br J Dermatol. 2020 Sep; 183(3): 471–479. With Photos A multicentre, randomized, double‐masked, parallel group, vehicle‐controlled phase IIb study to evaluate the safety and efficacy of 1% and 3% topical minocycline gel in patients with papulopustular rosacea G. Webster, Z.D. Draelos, E. Graber, M.S. Lee, S. Dh
  10. Admin

    AquaVive

    Thanks, correct spelling is Melazepam. We have that in our affiliate store so if anyone wants to check it out and purchase it the RRDi gets a small affiliate fee that helps us out a tiny bit.
  11. Admin

    AquaVive

    What is 'Malazapham' ?
  12. Do you think that any rosacea non profit organization would do any research as this paper suggests, "that this opens a horizon for more research in the link between the skin and nervous system,"? Most of the research on rosacea is profit motivated since the skin industry promotes and sponsors most of the clinical research papers on rosacea. In comparison to non profit rosacea research who would investigate this? Could a grassroots non profit organization for rosacea gather enough donations to investigate this subject? What do you think? For more information. Are you aware that PD is a
  13. Admin

    AquaVive

    I was thinking about buying Tom's Lotion (used only the shampoo for about three months, not the lotion) but my dermatologist asked me if I have ever tried Azelaic Acid, which I have heard about since 2007 but never tried it. So I took her recommendation and have been using Azelaic Acid and you can review my updates on this in my rosacea blog. I have tried a long list of treatments mentioned in my blog to try to clear the folliculitis in my scalp and nothing cleared it. The Azelaic Acid has been the only thing so far that has taken away the itch and has definitely improved it. I will continue t
  14. Admin

    AquaVive

    I have been using it for a few months and I like it and recommend it. It doesn't cure SD but it definitely is better than any other shampoo for SD.
  15. Admin

    Brady's Blog

    Just made these videos:
  16. Admin

    Brady's Blog

    Update on my progress with azelaic acid gel/Finacea with photos. Seems to be working. The itching in the scalp has stopped. There is some 'keratin' that I am able to scratch off in my scalp but it definitely has improved. I will see Dr. Harper on September 30.
  17. Could it be possible for a non profit organization for rosacea to sponsor cell and gene therapy for rosacea? Could 10K rosacea sufferers get together and each donate one dollar to sponsor an investigation into this type of therapy for rosacea? Only if you and 9,999 other rosacea sufferers decided to do this. What is cell and gene therapy? Watch this video by Novartis: If you are interested in sponsoring such an investigation into such research, read this post.
  18. *image - Robert Plutchik's Wheel of Emotions. A recent study came to the conclusion that "The emotions of Anger and Disgust have been poorly explored in empirical studies, despite they could be theoretically considered a vulnerability factor for the development of skin disorders and the dermatological extreme consequences, as negative emotionality toward self and the pathological skin condition." [1] Most clinical studies have focused on sadness, fear and anxiety which are the negative emotions related to skin disorders. However this paper concludes that "For most of the theories, an
  19. Admin

    Isotrexin

    Isotrexin is a topical gel containing 0.05% isotretinoin and 2% erythromycin indicated for the treatment of moderate acne vulgaris and is manufactured by GlaxoSmithKline (Ireland) which is owned by Stiefel Laboratories (Ireland) Ltd. - see product insert 2209530.PA1077_123_001.14879f44-cc4d-45fe-9d4e-a5a95f9374b8.000001Isotrexin PIL.180822.pdf
  20. In England, an article published in the British Journal of General Practioners, concludes that "Skin problems are the most common reason for a new presentation in primary care, and most patients with skin problems are managed exclusively in primary care" by general practitioners (GPs). Furthermore, "skin problems were usually presented alongside other complaints and resulted in a medication recommendation." This means that more patients in the UK apparently are being treated by GPs rather than dermatologists and the authors of the paper are concerned that "Shared decision making was uncommon a
  21. Diagnosis of rosacea has traditionally been done with a physical examination, history and 'qualitative human assessment [which] is often subjective and suffers from a relatively high intra- and inter-observer variability in evaluating patient outcomes,' [1] sometimes resulting in misdiagnosis. [2] A team of seven researchers at Ohio State University’s Department of Dermatology and the Wake Forest School of Medicine have developed an algorithm using AI, dubbed “Ros-NET,” that relies on digital images of rosacea patients to diagnose patients which according to the team works 88% to 90% correctly
  22. Brad Goreski, a celebrity fashion stylist and television personality, has rosacea. He has worked with Galderma in producing the following video: On August 20, 2020, Brad announced he has rosacea on his Facebook page.
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