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  1. * Sulphur or Sulfur* has been used to treat rosacea for over a hundred years. One patient with 'rosy drops' "was ordered Aug. 6, 1878, a mixture containing sulphate of iron and sulphate of magnesia, and for local application an ointment of sulphur, four parts, cosmoline, ninety-two parts. This was followed by rapid improvement, and when seen again on Sept. 17, all trace of the eruption had disappeared, and she felt much stronger and better." [1] "Sulfur acts as a keratolytic agent and also it has antibacterial activity. It also kills fungi, scabies mites, and other parasites. Precipi
  2. Rylar, keep us posted on your progress. Might want to read this post on GUT Rosacea. One treatment that may help which is natural and inexpensive is ElaineA's borax bath. Probiotics are another subject to consider.
  3. Azathioprine image courtesy of Wikimedia Commons A study has determined that if you are undergoing any immunosuppressive treatments, i.e., Tacrolimus, pimecrolimus, cyclosporine, systemic steroid, chemotherapy, systemic glucocorticoids, cyclosporine, methotrexate, or azathioprine treatments, or have an immunocompromised condition, i.e. HIV, chronic renal failure, acquired immunodeficiency syndrome, that this "might increase the number of mites and demodicidosis should be kept in mind in patients on immunosuppressive treatment." In those in the tested group treated with immunosuppre
  4. When rosaceans use drugs, whether prescription or non prescription, drug interactions are a concern when you take more than one drug to treat your rosacea. Whether the drug is oral, topical, tincture, toner, injection, or in whatever other form there can be drug interactions with other drugs, food or drink or some other unknown factor. First, let's be sure we agree on what a drug is so we are all on the same page and what a drug interaction is as well. Drug "A drug is any substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically disting
  5. Admin

    Brady's Blog

    Could someone explain to me why rosaceans prefer donating to the the NRS, the AARS, the ARSC, or the AAD instead of the RRDi? Why do they think it is ok for Sam Huff's two private corporations to receive about 60% of all the National Rosacea Society donations received over a twenty year period which amounts to over $9.8 million dollars (see spreadsheet) and they CONTINUE to donate to the NRS. Why is it that with over 1300 members in the RRDi no one posts? No one really cares if the RRDi dissolves? Really? It is so sad. I have given a lot of what I do for rosacea sufferers for FREE to a
  6. "South Dakota Gov. Kristi Noem on Monday announced a statewide clinical trial of hydroxychloroquine for the possible treatment of COVID-19, making her state the first in the country to institute a program exploring the potential effectiveness of the drug in treating and preventing coronavirus." South Dakota implements statewide hydroxychloroquine clinical trial for potential coronavirus treatment, Fox News
  7. Skin Manifestations in Coronavirus "The novel coronavirus may cause dermatological symptoms such as pseudo-frostbite, hives and persistent, sometimes painful redness, as symptoms that affect the body outside the respiratory system continue to be found that may be associated with coronavirus infections, according to the French National Union of Dermatologists-Venereologists (SNDV – skin and sexually transmitted disease doctors)." Dermatological symptoms may be the latest new coronavirus symptom Pseudo-frostbite, hives and redness may appear with or without respiratory symptoms. B
  8. Win a jar of the ZZ cream! Below are anecdotal reports of ZZ cream use collected over a great deal of investigative time for your benefit and the end notes show the source of the report usually found at RF since members at the RRDi are reluctant to post. The ones below are positive, and if you have the time you could post your investigation on the negative ones which I don't have the time for (maybe you do?). You may review my post on the ZZ cream and for a more recent update visit my blog (scroll down to my first comment) for a recent photo. I stumbled upon a negative post about the ZZ c
  9. I have experimented using the Blog tool that is provided for free for our members and posted a comment. Maybe members would like to create their own blog?
  10. Admin

    Brady's Blog

    Brady Barrows, March 2020 So I thought I would experiment with my blog to see if anyone is interested in what I am writing. With all the coronavirus news and having to stay at home, I have been spending more time with the RRDi writing posts and trying to get donations. It is mind boggling to me that with over 1300 members no one is posting and the donations are basically nothing to speak of and I wrote this post on March 20 explaining that if the RRDi doesn't get donations we will have to dissolve the non profit for rosacea and everyone will just have to live with the NRS, the AARS, the A
  11. Rosacea Research Every medical student learns about the risk-benefit ratio in medical research and in treatment. "For research that involves more than minimal risk of harm to the subjects, the investigator must assure that the amount of benefit clearly outweighs the amount of risk. Only if there is a favorable risk–benefit ratio may a study be considered ethical. The Declaration of Helsinki, adopted by the World Medical Association, states that biomedical research cannot be done legitimately unless the importance of the objective is in proportion to the risk to the subject. The Helsinki Decl
  12. Artemisia Image Courtesy of Wikimedia Commons "Artemisinin (ART), an anti-malaria drug, was reported to have several effects including anti-inflammation and anti-angiogenesis activities. However, the role of ART on rosacea remains unclear....ART ameliorated rosacea-like dermatitis by regulating immune response and angiogenesis, indicating that it could represent an effective therapeutic option for patients with rosacea." Biomedicine & Pharmacotherapy Volume 117, September 2019, 109181 Artemisinin, a potential option to inhibit inflammation and angiogenesis in rosacea Xin Yuan
  13. More has been uncovered in a report published in Cell Reports, April 7, 2020 by Balka et al. who report, "We further demonstrate that TBK1 acts redundantly with IkB kinase ε (IKKε) to drive NF- kB upon STING activation." While this may be daunting to understand for a layman, James Ives, News Medical Net, explains the significance of this, "The two signalling arms of the cGAS-STING pathway were thought to be mediated by a single upstream kinase, TANK binding kinase (TBK1)...."That basically told us that the mechanism that drives the second cytokine pathway depends on both proteins, but that th
  14. It is with sad hearts that Steve Johnson, D.O., who has served for many years on the RRDi board of directors has resigned due to his busy work at his clinic. Steve will be missed.
  15. One more differential diagnosis with rosacea is ruling out Demodex-induced follicular mucinosis (FM) from demodectic rosacea or for that matter, rosacea in general or of its variants. A report on this states, "Higher densities of mites correlate with increased perifollicular inflammation and clinical manifestations of disease. These cases support the hypothesis that a subset of idiopathic FM arises secondary to an aberrant immune response to Demodex. Given the typically robust response of Demodex to treatment with ivermectin, identification of this subset of patients would potentially provide
  16. Metronidazole (brand name Flagyl) has been used to treat rosacea for many years, not chiefly for its antibacterial component but more importantly for its anti-inflammatory treatment component. Metronidazole is also classified as an antiprotozoal treatment along with the larger category of anti-parasitic agents. Recently due to the coronavirus pandemic, metronidazole is being investigated to treat coronavirus. A paper published March 30, 2020 online in the Archives of Academic Emergency Medicine concluded, "Metronidazole, owing to its immunopharmacological behavior, plays a pivotal role in seve
  17. Image courtesy of Wikimedia Commons "Of note, some patients with COVID-19 with previous skin conditions such as rosacea, acne, eczema, and atopic dermatitis experienced a flare during the course of their disease." [1] Treatments for Rosacea and for Covid-19 These are the list of treatments for rosacea that are being investigated to treat the coronavirus: Azithromycin for Coronavirus Chloroquine for Coronavirus Doxycycline for Coronavirus Hydroxychloroquine for Coronavirus Ivermectin for Coronavirus Metronidazole and Coronavirus Naltrexone and Ket
  18. Hydroxychloroquine (brand name Plaquenil), a treatment for rosacea, [and the related drug, chloroquine (brand name Arelene)] has been in the news for its alleged ability to treat coronavirus, mostly due to President Trump’s advocacy on its use during the pandemic. President Trump suffers from rosacea. This subject has ‘divided the medical community’ according to The New York Times. The American Society for Biochemisty and Molecular Biology reports that there are few published papers on this subject, acknowledging that one small study in France was 'encouraging,' however, other reports indicate
  19. In a related news item, Ivermectin, another anti-parasitic drug, has been purported to treat coronavirus.
  20. In a related news item, Plaquenil (Hydroxychloroquine), another anti-parasitic drug, has been purported to treat coronavirus. Read the third post in this thread.
  21. "It’s still not clear exactly how Ivermectin works. But it appears to stop the processes that allow proteins to move within the virus. These proteins would normally dampen the body’s antiviral response, allowing the virus to replicate and enhance the infection." Head lice drug Ivermectin is being tested as a possible coronavirus treatment, but that’s no reason to buy it, April 6, 2020, Andrew McLachlan, The Conversation ----------------------------------------------------- "Wagstaff cautions that these are very early test results and much more will need to be done, including clinic
  22. There are multiple news reports that ivermectin, a common drug used to treat rosacea orally and topically, has been found effective in treating the coronavirus (scoll down for more reports). Virus and rosacea has never, ever been ruled out. Ivermectin is just one treatment for rosacea that is being investigated along with other rosacea treatments. A collaborative study led by the Monash Biomedicine Discovery Institute and the Doherty Institute found the drug Ivermectin stops coronavirus growing in cell culture." Warning issued as researchers reveal another potential treatment for c
  23. There appears to be a shortage of Hydroxychloroquine (HCQ) according to several news sources. So if you somehow receive Hydroxychloroquine (HCQ) treatment for covid19 and your rosacea improves, please find the green reply button in this thead to post your results. Furthermore, virus has never, ever been ruled out in rosacea. End notes Physicians Seek to Reassure Amid Hydroxychloroquine Shortage, Jeff Evans, March 27, 2020, Medscape FDA SAYS THERE'S A SHORTAGE OF HYDROXYCHLOROQUINE AND CHLOROQUINE 'DUE TO A SIGNIFICANT SURGE IN DEMAND, BY KASHMIRA GANDER ON 4/1/20 AT 11:58 AM EDT
  24. Frequently some are concerned that if they have a red nose that they will end up like WC Fields, the rosacea poster boy. This is due to a misunderstanding that rosacea progresses in stages which has been debunked. While it is possible if you don't treat your rosacea (or your red nose) it may get worse, it certainly does not mean that it will necessarily get worse or progress into 'stages'. Obviously WC Fields didn't care about whether his nose got redder or turned into rhinophyma, so it is good you are concerned about your red nose. The good thing about rhinophyma or what is more recently clas
  25. Coffee Extracts Protect Cells Against Oxidative Stress One of the many theories on the cause of rosacea is the Antioxidant System Defect Hypothesis which is related to Oxidative Stress, Ferritin and Rosacea. One paper concluded the following; "Further experiments using LPS-induced murine macrophages revealed that coffee extracts protect cells against oxidative stress by enhancing the content of the antioxidant GSH and stimulating expressions of the genes related with the cellular antioxidation system. Also, coffee extracts decreased the expression of proinflammatory cytokines and inf
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