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  1. Topical retinoids are mainly used for acne but there are some dermatologists prescribing Rx topical retinoids for rosacea, i.e., Differin (adapalene), Retin-A Micro (Tretinoin Microspheres), Tazret (Tazarotene), and others. "Also referred to as retinoic acid or vitamin A acid, topical retinoids are available as gels, ointments, creams, or foams to be applied directly to the skin. They work by promoting the exfoliation of dead skin cells as well as by boosting the production of new skin cells. The new cells then push dead cells and excess oil out of blocked pores. Retinoids also have anti-inflammatory properties." [1] "As an intermediary step between topical antibiotics and oral isotretinoin, we propose that topical tretinoin may be effective in the management and reduction of rosacea symptoms,” Emily Forward, MD, of the University of Sydney, said at the meeting. There has been recent discussion regarding the use of low-dose isotretinoin in the treatment of rosacea, but safety with long-term use is an issue, she noted." [2] "Expert groups and evidence-based guidelines agree that topical retinoids should be considered the foundation of acne therapy." So this article explains the increased use of retinoids by physicians over antibiotics since there is concern over antibiotic resistance. This article states, "The use of retinoids plus BPO targets multiple pathways and can often eliminate the need for antibiotics, reducing the likelihood of antibiotic resistance." [3] "Topical retinoids have clearly demonstrated benefit in rosacea. "Some dermatologists choose to avoid them, because they are more difficult to use, but over the long term, they really do make a difference for these patients," Dr. Pelle says. "In my experience, at one month you get an improved skin texture, at four months flushing is much less frequent, and at one year there is a normal flush response, substantially decreased redness and few to no flares requiring tetracyclines." " [4] There is a thread at RF that inspired this post. [5] There are a number of over the counter retinols available in our affiliate store. [6] What is the difference between a retinol and a retinoid? "Essentially, retinol is just a specific type of retinoid." [7] End Notes [1] What to Know About Topical Retinoids for Acne, Heather L. Brannon, MD, very well health [2] Topical tretinoin resolves inflammatory symptoms in rosacea, in small study [3] Increased Retinoid Therapy for Acne [4] 'Subtype-directed' approach targets rosacea, Jan 01, 2005, DermatologyTimes [5] Retinoid highly recommended by top-rated dermatologist on RRDi, beherenow [6] https://irosacea.org/search/?q=retinol&quick=1 [7] What’s the Difference Between Retinol and Retinoids, Marissa Laliberte, Reader's Digest
  2. We are pleased to announce that members can now post REVIEWS in our affiliate store. Here is a screen shot of a review: In the screen shot above the review can be viewed if you click on the tab PRODUCT REVIEWS and MEMBERS can RESPOND TO THIS REVIEW. So if you find an item in our store and you have used the item and want to review it all you do is, (1) Find the item in the store, (2) login with your RRDi account (only requires registering with an email address if you don't have an account), (3) Scroll down to the product information tab and next to this tab find the PRODUCT REVIEWS tab and click on it. (4} Find the WRITE A REVIEW black button and click on it (5) Write your review in the comment box
  3. A paper concluded that the GPSkin® Barrier device "determines TEWL and SCH accurately in healthy and impaired skin barrier state and can monitor skin barrier function in rosacea during treatment. The GPSkin device is much more practical compared to previous skin barrier tools when used in clinical practice.' [1] "Based on these findings, we concluded that GPSkin provides reasonably precise and reliable measurements of SC hydration and TEWL as compared to current devices." [2] "GPSkin Barrier® is a reliable, affordable, and versatile device for assessing epidermal permeability barrier function and SC hydration."[3] End Notes [1] Skin Res Technol. 2020 Jun 23;: Value of GPSkin for the measurement of skin barrier impairment and for monitoring of rosacea treatment in daily practice. Logger JGM, Driessen RJB, de Jong EMGJ, van Erp PEJ [2] Skin Res Technol. 2019 Sep;25(5):612-617. doi: 10.1111/srt.12692. Epub 2019 Apr 3. Validation of a Novel Smartphone Application-Enabled, Patient-Operated Skin Barrier Device Erin E Grinich , Anuja V Shah, Eric L Simpson [3] Skin Res Technol. 2019 Jan;25(1):25-29. doi: 10.1111/srt.12590. Epub 2018 Jun 4. Validation of GPSkin Barrier ® for Assessing Epidermal Permeability Barrier Function and Stratum Corneum Hydration in Humans L Y , Z Wang, Z Li, C Lv, M-Q Man
  4. Azelaic Acid 15% Foam (AAF) vs Metronidazole Cream (MC) and Metronidazole Gel (MG) "MG- and MC-treated patients more frequently reported treatment concerns and side effects than AAF-treated patients, and tolerability of those side effects was higher for patients treated with AAF. While treatment cost is a more frequent concern in patients treated with AAF, these patients less frequently reported concerns with treatment efficacy and reported similar or greater tolerance to side effects than patients treated with either MC or MG." J Drugs Dermatol. 2020 Mar 01;19(3):295-304 Rosacea Treatment Satisfaction: Matching Adjusted Indirect Treatment Comparison Analysis of Metronidazole Gel or Cream vs Azelaic Acid Foam. Williamson T, LaRose A, Cameron J, Lott J, Eaddy M, Hopson S, Shih HC, Tennant LT Conclusion So according to the above paper you probably should consider AAF over MC/MG and refer this paper to your dermatologist who is prescribing metronidazole instead of azelaic acid.
  5. The controversy about hydroxychloroquine continues. "Not all researchers have given up on the drug, however, and recent developments show it is not yet dead as a potential weapon against COVID-19, especially as a preventative in people not yet exposed to the virus." Hydroxychloroquine is not dead yet, Lisa Cavazuti, NBC News --------------------------------------------------------------------------------------------------- "Once praised as a miracle cure for covid-19, an antimalarial drug called hydroxychloroquine has rarely been out of the headlines since the start of the pandemic. It was hoped it might find a new use as a therapy in patients who are unwell with the novel coronavirus. But in recent weeks a scientific picture has emerged of a treatment that does not appear to be helping patients at all, and might even be causing harm. Whether it helps seems clear now: it doesn’t. When it comes to the harm, though, it turns out that the scientific literature may be misleading. On June 4th the Lancet, a respected medical journal, retracted a high-profile paper published only a month previously. This had suggested that hydroxychloroquine and its analogue, chloroquine, actually increased the death rate in hospitals when taken by those with covid-19. This led the World Health Organisation to halt its trials of the drug. It also caused considerable concern to patients and to those enrolled on other such trials." Hydroxychloroquine is embroiled in yet more controversy, The Economist
  6. Dr Sam Buntin discusses rosacea being one of the most common skin disorders, yet is often misdiagnosed as something else. Knowing you have it is key if you’re to avoid the many pitfalls associated with this volatile condition. She offers beauty and lifestyle choices that can actually aggravate rosacea. More with Dr. Buntin All you NEED to know about Rosacea with Dr Sam & Dr Emma Retinoids and Rosacea Five Skincare Cheats to Manage Rosacea | Dr Sam in the City ROSACEA WITH DR SAM BUNTING | TRINNY Rosacea Q & A with Trinny Woodall | Dr Sam Bunting 5 Skincare Rules You MUST Follow If You Have Sensitive Skin | Dr Sam Bunting A Derm-Approved Guide to Red, Sensitive Skin! | Dr Sam in The City How to Manage Rosacea in Winter | DERMSquared | Dr Sam in The City How To Tackle Big Pores | Dr Sam Bunting DR SAM BUNTING ON... ROSACEA | CAROLINE HIRONS | MARCH 2015
  7. Dermatologist Dr. Davindra Singh explains the causes of Rosacea and shares tips on how to treat the skin condition.
  8. "ImageJ is a Java-based image processing program developed at the National Institutes of Health and the Laboratory for Optical and Computational Instrumentation (LOCI, University of Wisconsin)." [1] ImageJ for Rosacea "ImageJ is a simple, rapid, objective and reproducible tool to monitor erythema in rosacea patients during treatment. The photographs allow retrospective analysis, evaluation of large and small lesions, and discrimination of subtle redness differences." [2] Open Source Java "ImageJ Ops is a framework for reusable image processing operations. Ops extends Java's mantra of "write once, run anywhere" to image processing algorithms." [3] "ImageJ and its Java source code are freely available and in the public domain. No license is required." [4] Download End Notes [1] ImageJ, Wikipedia [2] Skin Res Technol. 2020 Jun 14;: Evaluation of a simple image-based tool to quantify facial erythema in rosacea during treatment. Logger JGM, de Jong EMGJ, Driessen RJB, van Erp PEJ [3] "ImageJ is an open source Java image processing program inspired by NIH Image. It runs on any computer with a Java 1.8 or later virtual machine." ImageJ About [4] ImageJ Features
  9. A paper concludes, "The developed complex treatment of rosacea patients with combined and differentiated use against the background of standard therapy of antihistamines with anti-inflammatory activity of fast (containing bilastine) and prolonged action (ketotifen fumarate) and antioxidant drug ethylmethylhydroxypyridine succinate significantly improves both the immediate and long-term clinical results of treatment of such patients." [1] Ethylmethylhydroxypyridine is Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine). [2] It is also called Mexidol or Mexifin. Emoxypine is similar to pyridoxine, which has been discussed improving SD at this post at RF. It is available non prescription at Amazon through the RRDi Affiliate Store: Emoxypine Capsules (125mg x 60 capsules $26.99) Emoxypine (Mexidol) Succinate (125mg x 28 capsules $69.99) Emoxypine Succinate Capsules (125mg x 60 capsules $19.99 ) Emoxypine Succinate Powder (30 grams $54.99) Mexidol 50 Tablets (125mg x 50 tablets $26.50) Anecdotal Reports There are no known reports thus far. You could be the first one if you try it and find the green reply button and reply to this post. Mknlvi at RF started a thread on this subject and was the original source of this information. End Notes [1] DOI: https://doi.org/10.37321/dermatology.2019.3-4-04 Comprehensive treatment of rosacea patients taking into account the indicators of inflammatory mediators and the state of prooxidant-antioxidant homeostasis [2] Emoxypine, Wikipedia
  10. Thanks to David Pascoe at RSG, "A pre-proof version of an article to appear in the Journal of the American Academy of Dermatology details a small double blind study that found that oral hydroxychloroquine 200 mg twice a day offered similar benefits to rosacea sufferers compared to doxycycline 100 mg a day." [1] End Notes [1] Hydroxychloroquine works same as doxycycline for rosacea, David Pascoe, RSG Am Acad Dermatol. 2020 May 18;S0190-9622(20)30915-4. doi: 10.1016/j.jaad.2020.05.050. Online ahead of print. Efficacy and Safety of Hydroxychloroquine for Treatment of Patients With Rosacea: A Multi-Center, Randomized, Double-Blind, Double-Dummy, Pilot Study Ben Wang, Xin Yuan, Xin Huang, Yan Tang, Zhixiang Zhao, Bin Yang, Baoqi Yang, Yue Zheng, Chao Yuan, Hongfu Xie, Ji Li
  11. Secukinumab has been in clinical trial since 2017. A recent update from Healio states, "Patients treated with secukinumab for papulopustular rosacea saw significant improvements in quality of life and reduction of severity markers, according to a study presented at the American Academy of Dermatology virtual meeting." [1] Cosentyx is the brand name for secukinumab, which "is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is marketed by Novartis for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. It inhibits a member of the cytokine family, interleukin 17A." [2] "Secukinumab is a recombinant fully human IgG1/kappa monoclonal antibody and is manufactured in Chinese hamster ovary cells." [2] The clinical trial was small with only 23 participants over sixteen weeks. End Notes [1] Clinical Trials, Third Post, RRDi [2] Secukinumab, Wikipedia
  12. "The U.S. Food and Drug Administration revoked its emergency authorization for hydroxychloroquine, a controversial malaria drug promoted by President Donald Trump for treating the coronavirus. The agency said in a letter the decision is based on new evidence that made it unreasonable to believe hydroxychloroquine and chloroquine "may be effective in diagnosing, treating or preventing" COVID-19, the illness caused by the virus." Hydroxychloroquine: FDA pulls emergency use of malaria drug touted by Trump to treat the coronavirus Adrianna Rodriguez USA TODAY
  13. "The U.S. Food and Drug Administration revoked its emergency authorization for hydroxychloroquine, a controversial malaria drug promoted by President Donald Trump for treating the coronavirus. The agency said in a letter the decision is based on new evidence that made it unreasonable to believe hydroxychloroquine and chloroquine "may be effective in diagnosing, treating or preventing" COVID-19, the illness caused by the virus." Hydroxychloroquine: FDA pulls emergency use of malaria drug touted by Trump to treat the coronavirus Adrianna Rodriguez USA TODAY
  14. If you are convinced that avoiding sugar/carbohydrate improves your rosacea or other skin issue, yet you have a sweet tooth, you probably are on a search for zero calorie sugar substitutes. Of course, in the USA, the ones offered are massive, which a partial list is shown below may have zero calories or at the very least low calories. Image courtesy of Rosacea 101: Includes the Rosacea Diet, Brady Barrows So which one should you use? Of course, your preference is the king of decisions, but which one would be the most natural or healthiest one to use in this list? Stevia For years, Stevia was the one most health authorities choose. However, according to Healthline, "The use of stevia in foods is a bit confusing. The FDA Trusted Source hasn’t approved whole leaf or crude stevia extracts as a food additive. Despite being used for centuries as a natural sweetener, the FDA considers them unsafe. They claim literature indicates stevia in its most natural form may affect blood sugar. It may also affect reproductive, renal, and cardiovascular systems." Medical News Today points out, "Some people have allergic reactions to steviol glycosides that are not extremely pure. Stevia is part of the Asteraceae plant family, which includes daisies, sunflowers, and chrysanthemums. Anyone with allergies to these plants or others in the family should avoid stevia products." Luo Han Guo (Monk Fruit or Siraitia grosvenorii) Therefore, Luo Han Guo (Siraitia grosvenorii or monk fruit) is emerging as a better choice. The safety is beyond any doubt since it is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. "The plant is most prized for its sweet fruits, which are used for medicinal purposes and as a sweetener. In traditional Chinese medicine, it is used for cough and sore throat and in southern China it is believed to be a longevity aid. The fruits are generally sold in dried form, and traditionally used in herbal tea or soup." [1] (image courtesy of Wikimedia Commons) Monk Fruit "The interior fruit is eaten fresh, and the rind is used to make tea. The monk fruit is notable for its sweetness, which can be concentrated from its juice. The fruit contains 25 to 38% of various carbohydrates, mainly fructose and glucose. The sweetness of the fruit is increased by the mogrosides, a group of triterpene glycosides (saponins). The five different mogrosides are numbered from I to V; the main component is mogroside V, which is also known as esgoside." [1] Monk fruit is available in liquid, granule, and powder forms and is safe for children, pregnant women, and breast-feeding women. Monk fruit gets its sweetness from antioxidant mogrosides. One study found monk fruit extract has the potential to be a low-glycemic natural sweetener. [2] Another study concluded mogrosides may help reduce oxidative stress. [3] Available in the RRDi Affiliate Store Namanna Organic Monk Fruit Natural Sweetener NatriSweet Monk Fruit Extract Now Foods, Organic Monk Fruit Liquid End Notes [1] Siraitia grosvenorii, Wikipedia [2] Yao Xue Xue Bao. 2009 Nov;44(11):1252-7. Insulin Secretion Stimulating Effects of Mogroside V and Fruit Extract of Luo Han Kuo (Siraitia Grosvenori Swingle) Fruit Extract Ying Zhou, Yan Zheng, Jeff Ebersole, Chi-fu Huang [3] Braz J Med Biol Res. 2013 Nov; 46(11): 949–955. Antioxidant effect of mogrosides against oxidative stress induced by palmitic acid in mouse insulinoma NIT-1 cells Q. Xu, S.Y. Chen, L.D. Deng, L.P. Feng, L.Z. Huang, and R.R. Yu
  15. One report indicates that ivermectin was successful in treating Pityriasis folliculorum. [1] "An association with pityriasis folliculorum has also been described [with demodicosis]." For more information [1] Pityriasis Folliculorum: Response to Topical Ivermectin.J Drugs Dermatol. 2017 Dec 01;16(12):1290-1292Darji K, Burkemper NM
  16. Admin

    AquaVive

    Just received today Tom Busby's AquaVive shampoo. If you haven't heard about it, you will. Tom is the SD Expert Extraordinaire at RF and formulated the shampoo. I will update my progress with this thread. The details on this can be read below: Review_of_OTC_Treatments_for_Malassezia _skin_conditions-for_Aquavive.pdf Tom Busby has given the RRDi permission to post his email address if you want to know more about this shampoo: busbylaw@cox.net Be sure to mention to Tom that you read about this at the RRDi.
  17. "Grassroots movements are associated with bottom-up, rather than top-down decision making, and are sometimes considered more natural or spontaneous than more traditional power structures." [1] The RRDi is a grassroots organization founded by rosacea sufferers who are volunteers. The board of directors are all rosacea sufferers and their motive to volunteer is to help rosacea sufferers. Now compare that with who serves on the 'other' rosacea non profit organizations board of directors. [2] As far as we know there are only three other rosacea non profit organizations (ARSC, AARS, and NRS) and possibly one other, the AAD that might spend a tiny, tiny bit of money on rosacea research. All the board members of these 'other' non profits are NOT rosacea sufferers and are mostly comprised of businessmen and medical professionals (dermatologists) who have a vested interest in rosacea since they may receive a salary or benefit from money spent on private contractors used by the non profit organization, or receive compensation for attending conventions or meetings sponsored by the non profit organization. Follow the money where the non profit spends the most of its donations on, and if you take the time, you will discover it is very little on rosacea research. You may wonder how non profits work? The members of the RRDi are mostly rosacea sufferers [rosaceans] and have a say who serves on the board of directors of the RRDi (the charter requires that the board members suffer from rosacea). The board of directors of the RRDi are sometimes chosen by the other board members but every five years the voting members of the RRDi may vote who may continue to serve on the board of directors. The members could replace the entire board of directors. This is bottom up decision making. The other non profit organizations are NOT grassroots and work from the top down. How do the other non profit organizations choose their board members. Top down decision making. What Motivates Board Members? Money is the motive on who makes the decisions on the spending of the donations with the 'other' rosacea non profits and if you follow the money you will find that the board of directors make sure they benefit in some monetary way. This is a top down direction since the other non profits are run by NON rosaceans and have their own personal agenda so that members of the board somehow benefit with some compensation with the spending of the donations. Money is usually at the root of any top down decision making process. Grassroots Motive So if you have similar grassroots philosophy why not join the RRDi and volunteer. If money is your motive, go to the 'other' rosacea non profits. [2] If volunteering by helping other rosaceans is your motive, you have found the only grassroots rosacea non profit organization on planet earth. [3] Only One Non Profit Organization Run by Rosaceans There is only one non profit organization for rosacea founded by rosacea sufferers, this one, the RRDi. All the others are founded by non rosaceans and all you do is see who is serving on the board of directors and note how the board members on each rosacea non profit benefit how the donations are spent (each board determines how the donations are spent). Follow the money (where does most of the donations end up being spent on?). Donations Spent on What? If you could gather together say 10K rosaceans into one non profit organization for rosacea and fund a paper on a rosacea topic and receive from each member donating just one dollar, it would be a cinch to get a reputable medical clinician to investigate further into whatever topic is chosen and nail it to the wall with a double blind, placebo controlled, peer reviewed study. However, if you did get 10K rosaceans together to donate each $1 that would be a miracle in itself. What might that subject be? Alas, this dream, which began over sixteen years ago with the RRDi was formed, hasn't brought about such unity among rosacea sufferers. Instead, rosacea sufferers are splintered into private social media groups, i.e., Facebook, Instagram, Reddit, etc. and continue to parrot the non profit organizations for rosacea that are run by non rosacea board members. And rosaceans prefer and love it that way. Does these social media rosacea private groups engage in any rosacea research? Grassroots Glimmer of Hope for Rosacea However, there is perhaps a glimmer of hope. The owner of the Rosacea Forum, [rosaceagroup.org] formed a non profit organization [RRF] about fifteen years ago and gathered together a group of rosacea sufferers and collected a total of $16K and donated all of this to the NRS. So, it can be done. However, the RRF non profit for rosacea dissolved. What happened? Read for yourself. This example of the RRF is a grassroots non profit that actually did something in sponsoring their own research, except they gave the $16K to a non profit that is run from the top down. A brief glimmer of grassroots for rosacea. Grassroots Non Profits Another example of an excellent grassroots non profit organization is the The Erythromelalgia Association which actually sponsors their own research so it can be done. Is a grassroots motive something to consider, or are you content with the current status quo rosacea research being done by the 'top down' decision making process of the 'other non profits for rosacea' whose board members are not suffering from rosacea? End Notes [1] Grassroots, Wikipedia [2] Links, Other Non Profit Organizations [3] Volunteering What Community Support Means to You?
  18. If you look at the photos of the "erythematous scaly plaques on the eyelids, cheeks, nose, nasolabial folds, and chin" of this 16 year old male suffering from Netherton syndrome who was successfully treated with secukinumab, it looks a bit like SD. It would be interesting to see if this treatment works on SD or rosacea? Who would sponsor such a research clinical paper? Could 10K members of the RRDi be united enough to each donate one dollar so we could sponsor such a research investigation? Wouldn't you like to know if secukinumab would treat your skin issue? Ask you physician. Post in this thread your results. Why not be a RRDi volunteer and post your comment about this? Find the green reply button. It is not that difficult to register an account with just your email address. Of course, volunteering is not for sissies. "At his most recent follow-up after almost 3 years of treatment with secukinumab, he had complete clearance of his facial erythema and only 1 mild flare of the polycyclic plaques on his trunk and extremities several months before."JAAD Case Rep. 2020 Jun; 6(6): 577–578.Successful use of secukinumab in Netherton syndromeSarah K. Blanchard, MD and Neil S. Prose, MD
  19. "Facial flushing, telangiectasias, inflammatory papules and pustules, facial burning/stinging sensation, skin dryness, edema, and ocular manifestations are characteristics of rosacea." Dermatol Online J. 2020 Feb 15;26(2): Full text The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders. Saric-Bosanac S, Clark AK, Sivamani RK, Shi VY
  20. "Discoid lupus erythematosus (DLE) is a chronic inflammatory erythematous skin disease that can be triggered by several factors. Rosacea is another skin disease that causes facial redness and tenderness. Demodex mites have been reported in rosacea and DLE patients commonly in the literature. These two diseases can be seen concomitant, mimic each other clinically and share common possible etiologic factors." Dermatol Ther. 2020 Apr 10;:e13394 Demodex positive discoid lupus erythematosus: Is it a separate entity or an overlap syndrome? Dursun R, Durmaz K, Oltulu P, Ataseven A
  21. "In each species, clinical and molecular studies have shown that the host's immunological interactions with Demodex mites are an important, but not fully understood, aspect of how Demodex can live in the skin either as a harmless commensal organism or as a pathogenic agent." J Eur Acad Dermatol Venereol. 2020 Apr 15;: Demodex: A skin resident in Man and his best friend. Foley R, Kelly P, Gatault S, Powell F
  22. Subungal Discoloration with Hemotoma or Disease A subungal discoloration usually is associated with a hematoma on finger or toe nails. [1] There are numerous images associated showing this available in a google search. However, subungal discoloration can be associated with disease. "Subungual discoloration carries a broad differential including infectious, inflammatory, metabolic, malignant or systemic diseases. Knowledge of this side effect is crucial in order to avoid unnecessary testing in determining the etiology of the subungual discoloration. Knowledge of this side effect is crucial in order to avoid unnecessary testing in determining the etiology of the subungual discoloration." [2] Subungal Discoloration with Tetracycline Long Term Use The authors of one paper on this subject explain that it is important to let patients know that long term use of tetracyclines, i.e., doxycycline, minocycline, for rosacea this subungal discoloration may be one of the side effects and risks. The report states, "We report on a case of a patient who has been on long-term minocycline use for adult acne management. He was initially on minocycline for six years, but due to minocycline-induced hyperpigmentation of his ears and fingernails, he had switched to doxycycline. One year later, the skin hyperpigmentation of the ears regressed; however, the blue subungual hyperpigmentation of his hands progressively become more prominent without any other significant symptoms." [2] End Notes [1] Subungual hematoma, Wikipedia [2] Cureus. 2020 Apr 24;12(4):e7810 Out of the Blue: A Case of Blue Subungual Discoloration Associated with Prolonged Tetracycline Use. Ahmad Y, Boutros H, Hanna K
  23. "Head-to-head trials show that azelaic acid and ivermectin might be slightly better than metronidazole." Topical treatments for rosacea. Can Fam Physician. 2019 Nov;65(11):803 Fritsch P, Kolber MR, Korownyk C
  24. "A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon‐beta, and other potential drugs have been studied for COVID19 treatment. We reviewed the potential dermatological side‐effects of these drugs." Dermatol Ther. 2020 May 22 : e13476.doi: 10.1111/dth.13476 [Epub ahead of print] Cutaneous sıde‐effects of the potential COVID‐19 drugs Ümit Türsen, Belma Türsen, Torello Lotti ============================================== "The US now has more hydroxychloroquine than it knows what to do with following a series of studies that concluded the drug is an ineffective and potentially dangerous treatment for COVID-19. The federal government, which started stockpiling the drug in March, now has 63 million surplus doses of the drug, donated by companies including Novartis, and another 2 million doses of chloroquine, the New York Times reports. Some 31 million doses from the Strategic National Stockpile were distributed before the FDA withdrew its emergency authorization of the drug to treat the coronavirus. President Trump championed the drug for months, hailing it as a possible "game-changer" and announcing that he was taking it himself." US Is Stuck With 63M Doses of Hydroxychloroquine, Rob Quinn, Newser ============================================= With the recent news that oral hydroxycholoroquine is just as effective as oral doxycycline for rosacea, maybe we will be hearing more anecdotal reports of hydroxycholoroquine improving rosacea? A report published in the Journal of the American Academy of Dermatology reports that oral hydroxychloroquine is just as effective as oral doxycycline. [see post no 7 in this thread by scrolling down for the clinical paper source associated with this]
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