Guide

100 Active Subscribers Need to keep the RRDi going. If you can donate two dollars a month (minimum is one dollar if your subscribe for three or more months) by subscribing to the RRDi for one year as an active member this should be enough to keep the RRDi going. Please seriously consider this. Thanks. If you can only donate for one month we request $2 since that helps with the PayPal or Stripe fee we incur when you join.

"Microneedling, also known as collagen induction therapy, is a common dermal therapy that utilizes devices that penetrate the dermis to a uniform depth, creating a controlled skin injury. This injury induces rapidly healing micropunctures with subsequent stimulation of collagen and elastin fiber production, resulting in skin remodeling and rejuvenation.9 Microneedling was originally performed with handheld rollers for treating acne scars, stretch marks, wrinkles and facial rejuvenation; however, microneedling devices have more recently been combined with the delivery of radiofrequency energy to heat underlying layers of skin and enhance dermal remodeling and improved clinical outcomes." J Clin Aesthet Dermatol. 2022 May; 15(5): 12–18. An Open-label Study Assessing the Efficacy and Tolerability of a Post-treatment Skincare Protocol Following Radiofrequency Microneedling for Facial Rejuvenation Elizabeth Grieshaber, MD, Alison Glorioso, CMA

A report indicates the following about the 'choice of vehicle' in treating rosacea: "The choice of vehicle is an important consideration in the treatment of acne and rosacea." [1] For example, some report irritation using the Cetaphil 'Basis for Vehicle' using Soolantra. [2] Some treatment vehicles cause not only irritability but also dryness or other issues that are termed 'adverse events' (AEs). This same report puts it succinctly: "Although topical therapy should avoid AEs associated with systemic medication administration, the efficacy, safety, and tolerability of topical therapy is influenced by percutaneous penetration, retention at the target for a sufficient time to obtain the desired therapeutic effect, and avoidance of adverse local reactions that may affect adherence. It has been noted that the drug product is only one of multiple components that determine the efficacy and tolerability of topically applied therapies such that the performance of a topical medication is also influenced by characteristics of the vehicle formulation that may influence penetration, permeation, irritancy, and patient preference." [1] The report "summarizes drug delivery systems that have been developed with the aim of improving outcomes for patients being treated for either acne or rosacea." [1] "In liquid and gel formulations, the bulk excipient that serves as a medium for conveying the active ingredient is usually called the vehicle. Petrolatum, dimethyl sulfoxide and mineral oil are common vehicles." [3] End Notes [1] J Clin Aesthet Dermatol. 2022 May; 15(5): 36–40. Enhancing Topical Pharmacotherapy for Acne and Rosacea: Vehicle Choices and Outcomes Lawrence J. Green, MD and Edward Lain, MD [2] Soolantra Mechanism of Action & Basis for the Vehicle (requires subscription) [3] Excipient, Vehicles - Wikipedia

The RRDi used to have a sister site relationship with the Rosacea Forum (RF), since one of our board members founded RF. David Pascoe, owner of Rosacea Support(RS), took over RF a while back. For many, many years, the RRDi and RF never had any advertisements like RS has done for years. Recently, in the past month or so, David has chosen to put advertisements on RF to help pay the bills since hosting a forum like RF is an expensive endeavor. As David points out in his reasons why he did this in this thread, the RRDi is in a similar situation and need donations to keep paying the bills which as everyone has noticed their bills are inflating and price increases on hosting are also feeling the crunch. The Invision Community platform which we have chosen to use since 2006 increased their hosting price this year by over 500%. The RRDi has chosen to resolve this with switching to a subscription based website. To access 95% of our rosacea data will require a minimum of at least $2 for one month's access or $3 for three months access. We hope this is the solution. The other option is to do as David has done with RF and put advertisements all over the website while browsing for rosacea data in the hope that these advertisements generate enough revenue to keep the site going. A third option is to have some rich donor sponsor the RRDi to keep the lights on. We still allow free posting here in our guest forum, so you can post a question about rosacea or make a comment about rosacea in our guest forum without registering and can hide behind a cryptic display name and no one ever knows who you are. Or you can donate a small donation either $2 or $3 and gain access to a wealth of rosacea data as a subscribed member. The RRDi would like some feedback in our decision to switch to a subscription based member forum. Why not find the REPLY TO THE TOPIC button and hide yourself behind a cryptic display name of your choice and tell us what you think?

'An association between coffee drinking and a lower risk of death is well-established: A 2019 analysis found that drinking two to four cups a day lowered a person's risk of death relative to people who didn't consume coffee. Another analysis suggested that consuming three to four daily cups lowered the risk of dying from heart disease compared to no coffee at all. The same research found that coffee drinking was associated with a decreased risk of Parkinson’s disease, chronic kidney disease, Type 2 diabetes and certain cancers." Drinking coffee may be linked to lower risk of death, even with a little sugar, Health News, Aria Bendix, NBC Annals of Internal Medicine Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality A Large Prospective Cohort Study Dan Liu, MD, Zhi-Hao Li, MD, Dong Shen, MD, Pei-Dong Zhang, MD, Wei-Qi Song, MSc, Wen-Ting Zhang, MSc, Qing-Mei Huang, MD, Pei-Liang Chen, MD, Xi-Ru Zhang, MD, Chen Mao, MD Annals of Internal Medicine The Potential Health Benefit of Coffee: Does a Spoonful of Sugar Make It All Go Away? Christina C. Wee, MD, MPH Eur J Epidemiol. 2019 Aug;34(8):731-752. Coffee consumption and all-cause and cause-specific mortality: a meta-analysis by potential modifiers Youngyo Kim, Youjin Je, Edward Giovannucci JAMA Network August 2018 Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism Findings From the UK Biobank Erikka Loftfield, PhD; Marilyn C. Cornelis, PhD; Neil Caporaso, MD; Kai Yu, PhD; Rashmi Sinha, PhD; Neal Freedman, PhD

There are simply two sub forums available to guests: Guests or Feedback Subscribed Members To view the vast amount of rosacea topics you will need to subscribe. You may be having issues trying to navigate our website using a mobile device so here is a helpful tutorial to find Rosacea Topics. Watch Video. You will have to register as a member to view some of the content below. Step one - Finding the Menu on the Home page (iOS - hopefully Android users are similar) - Look for the three bars top right corner (click): You should then see the following menu: Just under the HOME button find the NAVIGATOR button and click on it and you should see the following menu: The first word 'Navigator' is simply the title of this menu (don't click on it). The menu choices are now shown below this word, 'Navigator,' and you should begin scrolling down till you see the following: The menu button ROSACEA TOPICS is the second to the last choice. Click on ROSACEA TOPICS which brings you to the following screen: You may want to turn your mobile device horizontally to view the videos and subforums and scroll down to see all the choices: Now you can view the subforums but you are not allowed to enter a subforum without being a member of the RRDi. Membership requires a subscription and all you do register and then you can view over 7K posts and over 5.4K rosacea topics. Learn more. Hope this helps mobile device users on how to navigate our website. If you have questions, find the reply to this topic button and ask.

"Meet Demodex, the face mite, a microscopic arachnid that lives on human skin. The pore is its humble abode and the waxy sebum we secrete is its meal of choice. It's hard to know for sure, but there are likely many thousands of mites living on our faces at any given time, as BBC Reel's Melissa Hogenboom explores." There are thousands of mites living on your face, BBC More Information on Demodex

This is just a helpful tip for those of you with an iPhone using the Photos app so you can show a history of your rosacea to your dermatologist by simply creating an album that shows a history of selfie photos of your rosacea flareups over a period of time. Follow the directions from Apple on how to do this. You could name the album MyRosacea and designate which photos in the album to easily find it and show these images to your dermatologist. Android users probably have a similar way to do this. If you really care about helping your fellow rosaceans and have an Android, wouldn't it be helpful to explain in this thread how Android users could similarly have an easy way to show a history of photos of all the selfies taken to record rosacea flareups on an Android? It is important to have a record of your rosacea flareups for your dermatologist to review to show if your rosacea is progressing worse. You should know about the stages of rosacea. (requires subscription to view)

The Rosacea Diet has been around for sometime now. Dr. Ken Berry explains it below: LEARN MORE Forum Home > Forums > Member Forum > Rosacea Topics > Trigger Avoidance > Diet Triggers (Requires Subscription)

If you are not aware of Dr. Zach Bush you should be. Watch this video regarding how inflammatory diseases such as rosacea are on the rise and his insight into this and what to do about it. This is also related to GUT Rosacea.

Just an update on the previous announcement mentioned above, consider this Version 2. As the treasurer I have been trying to keep the RRDi non profit organization going with over a hundred videos and keeping the website going switching over to a subscription service (watch Rosacea Episodes S3:E1 and announcement) as well as sending out our latest newsletter to members (read the last newsletter dated 5/12/22). Yesterday, I went to a family reunion with my siblings and in-laws and had a short discussion with my sister-in-law who happens to be an editor for a prestigious journal in the scientific world and she explained to me that calling our ‘magazine’ a ‘journal’ is what is the issue since the title ‘journal’ implies it is a scientific journal with peer reviews and since we don’t have the funds to accomplish this since we have no rich donors, nothing to sell, and our income is derived solely from affiliate links from our store and now subscriptions to our website, we should simply use our newsletter tool we purchase through Invision Community as the medium to provide not only pro bono articles from the RRDi MAC but also from our members who may want to publish an article on rosacea. So instead of any article you wish to submit for our newsletter please follow the instructions mentioned in our previous post if you are a subscribed member of the RRDi. From henceforth, the Newsletter of the RRDi will only be available to subscribed members and we will be asking for a donation from those who do not subscribe to read the newsletter. Then, if we can obtain the funds through donations we may be able to resume publishing the Journal of the Rosacea Research and Development Institute again properly with a peer review process. We will mention any featured posts from RRDi members who post in the category of their choice in our member forum with a link to your post. So login to your RRDi member account and post your thoughts on rosacea. It may be considered as worthy of mentioning in a blurb mentioned in the next edition of the Newsletter of the RRDi.

Good question. The answer is social media. Learn more.

Learn More Azelaic Acid has been used to treat rosacea for many years. The brand name is Finacea, which is usually very expensive. We have information on savings card as well as generic azelaic acid prescriptions at this post. (member subscription required) There are a number of over the counter treatments using azelaic acid found in our store. Use the search tool and note the results of items found in our store. "Azelaic acid (AzA) is an organic compound with the formula HOOC(CH2)7COOH. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of a number of hair and skin conditioners. AzA inhibits tyrosinase." Wikipedia

"...Caffeine is both a Vasoconstrictor and a Vasodilator....it acts as a Vasoconstrictor (constricts blood vessels) to the muscles in the head and neck only, which is why it is so helpful for headaches.... it is also a Vasodialator (expands blood vessels) but this is to the rest of the body. Caffeine has three metabolites (by-products) one of which is Theobromine which when broken down by the liver causes a dilation or opening effect of blood vessels to a majority of the body. This is where it would come into play pre-workout as it can help with the “pump” or delivery of blood flow to the muscles..." What is the deal with Caffeine? Body Solutions

"Sarecycline (trade name Seysara; development code WC-3035) is a tetracycline-derived antibiotic. In the United States, it was approved by the FDA in October 2018 for the treatment of moderate to severe acne vulgaris". Wikipedia What about rosacea? Learn more below (members only😞

Watch the Full Length Nine Minute Video Watch the TRAILER below:

"A thorough understanding of the anatomy of the facial muscles is therefore essential when treating the perioral area with botulinum toxin to ensure the safe delivery of this medication." J Clin Aesthet Dermatol. 2022 Apr; 15(4): 12. Anatomical Exhortations of Botulinum Toxin Injections for Rosacea Tamara Searle, BSc, Faisal R. Ali, PhD, MRCP, and Firas Al-Niaimi, MRCP

"Social media has an influence on acne treatment..." Cureus. 2022 Mar; 14(3): e23169. The Influence of Social Media on the Treatment of Acne in Saudi Arabia Monitoring Editor: Alexander Muacevic and John R Adler Reem K Bahaj, Zahraa H Alsaggaf, Mohammed H Abduljabbar, and Jehad O Hariri

The RRDi is pleased to announce we are sponsoring a second edition of the Journal of the Rosacea Research & Development to be published later this year. We are accepting article submissions on the subject of rosacea from RRDi Members only. If you would like to submit your article for consideration to be published in the next edition follow these directions. (Members Only)

RRDi Site Index

For fifteen years (2006 thru 2020) we encouraged free registrations which required at the very minimum an email address to become a RRDi member. We had over 1000 registrations which included contact information, i.e., names, phone numbers and mailing addresses who were designated VOTING MEMBERS. Then in July 2017 we allowed NON VOTING members to register with JUST AN EMAIL address and this decreased our membership slightly but did notice that more chose this registration over including their contact information! We now had over 500 non voting registrations compared to over 1000 who did give us contact information. From this we discerned that privacy is a paramount issue with rosaceans. From April 2006 thru June 2017 members were required to give us names, mailing addresses and phone numbers to be a voting member of the RRDi which is a total of 135 months and we registered 1056 members (average 7.8 registrations/month). From July 2017 thru January 2021 (43 months) we allowed NON VOTING members to just register an email address with out names, addresses, or phone numbers and this period we decreased our registrations (333 registrations) slightly to an average of 7.7 registrations/month. So this may or may not have helped at all. Then in February 2021 we did something dramatic. We closed off most of our website to just members only and allowed GUESTS to view just a small percentage of our website requiring guests to REGISTER (with just an email address) to view the vast majority of our rosacea content categorized in logical forums. We noticed an increase in registrations dramatically. So for one year (February 2021 thru January 2022) we increased our registrations by 262 which is an average of 21.8 registrations/month! However, membership during this period was free! Most only registered with just an email address or used the Sign in with Apple registration. Then in February 2022 we required initially a subscription fee of $1 to access the member forum and discovered that PayPal gets 51 cents processing fee and the RRDi only received 49 cents. We decided immediately to increase the subscription to a minimum of $2/month (allowing discount subscriptions at $1/month for three or more months). Registrations decreased significantly to only four paid subscriptions during this period (February thru April). We do waive the subscription fees for certain volunteers. However, not everyone wants to volunteer. We have noticed that most guests are not willing to pay for a subscription to view our rosacea data. Google Sheet on History of RRDi Registrations The current cost of keeping this website going along with keeping up with non profit registrations in two states, etc., and all other expenses is about $1200/year. That is because we don't have salaries or pay private contractors or having board members, or any other members take 60% of the donations (learn more). Everyone here at the RRDi are volunteers in the true sense, no paid salaries like so many other non profit organizations do. We need a core of about 100 members who are willing to pay $1/month for an entire year by subscribing for our 12/month subscription which would keep it going. We are keeping a record in our financial report of the registered subscription members user names if you scroll down to our 2022 Financial Report to the subheading "Donations." All subscriptions are tax deductible. If we can get 100 subscribers donating at least $1/month we could probably keep the RRDi going. Any thoughts on any of this? If you think you can do a better way to keep this non profit patient advocacy grassroots organization going, all you gotta do is reply to this post and post your thoughts, critique, comment or complaint.

FREE jar of the ZZ cream! Below are anecdotal reports of ZZ cream use collected over a great deal of investigative time for your benefit and the end notes show the source of the report usually found at RF since members at the RRDi are reluctant to post. READ MORE - REQUIRES SUBSCRIPTION