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Rosacea Spread to Other Skin Areas? Want to learn more? Requires subscription.
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Methods and Tools Used to Quantify
There are a number of methods or tools used to quantify demodex density counts. We will continue to update this page as we learn more. (requires you join the RRDi to view)
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Combined therapy was superior in decreasing the D. folliculorum count in all groups and in reducing the mite count to the normal level in rosacea and in anterior blepharitis. On the other hand, the two regimens were comparable in reducing the mite count to the normal level in acne and peri-oral dermatitis lesions.
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3D medical animation still of Cytokines that are important in cell signaling. Image courtesy of Wikimedia CommonsWhile more rosacea research has been focused since 2007 on Cathelicidin, (requires subscription), other cytokines are emerging as a possible link to rosacea. To LEARN MORE required you register a subscription.
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Image courtesy of Wikimedia Commons Image courtesy of Wikimedia CommonsA "study demonstrated a significant impact of the COVID-19 pandemic on the public interest in dermatology." This same report stated that in some periods during 2020 that "An initial decrease in interest was followed by a significant increase for acne, comedones, melasma, rosacea, botox, dermaroller, and peeling."
To Learn MORE requires you join the RRDi
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There is a difference between a pharmacist and a compounding pharmacist. Whether your insurance covers a compounding pharmacist is another matter you will need to investigate. A prescription from a medical doctor is usually required for the compounding pharmacy to make the prescription. The base ointment can be any type the pharmacist has available or prescribed by the physician. This is like the old fashioned pharmacist who has a motar and pestal. Some rosaceans have learned using a compounding pharmacist for prescription treatments help. To learn more requires you join the RRDi to view our investigative report on this subject.
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image courtesy of WikiMedia CommonsA clinical study has confirmed that the most common allergens rosacea patients suffer contact dermatitis are certain specified ingredients which you can investigate yourself in this post. (Only Members can View this post by Joining the RRDi as a subscriber)
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There is at least one paper that includes Chloroquine (Aralen, Chloroquine FNA, Resochin, Dawaquin, and Lariago) along with Mepacrine in the treatment of rosacea. For more information (requires you join the RRDi) -
Could it be possible for a non profit organization for rosacea to sponsor cell and gene therapy for rosacea? What is cell and gene therapy? Watch this video by Novartis:
If you are interested in sponsoring such an investigation into such research, read this page.
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There has been a debate about whether carbohydrate is essential for human survival. Some will argue that it is. We have an investigative article on this subject (requires you join the RRDi). What has this to do with rosacea? Carbohydrate is a rosacea trigger.
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There is a poll at RSC where only a few responded but the highest number of votes say that sugar is the biggest rosacea trigger:
The above poll should be proof enough that sugar is a rosacea trigger. But to convince some others it takes more proof. Since the NRS goes by surveys (anecdotal reports) to make a list of rosacea triggers this post (requires you join the RRDi to view) is to show beyond any reasonable doubt that sugar and carbohydrate are rosacea triggers based upon the reports found at online rosacea groups. -
Rosaceans Diagnosing on the Internet
What we are discussing in this post is trying to get a rosacea diagnosis from other rosacea sufferers in rosacea social media groups, which technically is 'diagnosing on the internet.' We are not focusing about getting a diagnosis online from a dermatologist, which is a better idea that we will discuss in depth in this post and makes way more sense than asking rosaceans (rosacea sufferers) in social media groups. -
If you appreciate all the data on rosacea that you see available on the RRDi website in your search for a way to control your rosacea and found this helpful and would like to keep this non profit organization for rosacea a viable and productive web resource, can you donate two dollars to keep the RRDi going? We rely solely on donations. No one is getting paid or receives a salary. The RRDi staff are working pro bono as volunteers who care about rosacea sufferers. Note below what Margaret Mead was asked by a student that is related to what you can do for rosacea sufferers. Do you care about rosacea sufferers? If you have rosacea, you may have compassion to care for other rosaceans as she points out below.
A 15,000 year old bone and the Fall 2013 issue of Reflections, Jeffrey Oak ’85 M.Div., ’96 Ph.D., Yale Divinity School
RRDi Non Profit Organization
You may have your idea how a non profit organization for rosacea should be run and there are other non profits for you to choose giving your support. We would hope you appreciate how different the RRDi is run and that you approve of how it is run by donating two dollars to help keep the RRDi going. In May 2020 we have over 1400 plus members. If each member donated just one dollar (minimum two or one dollar a month for twelve months) it would be enough for our non profit to remain viable for about a year! Just think of the power of one dollar with so many members. That is less than the cost of a cup of coffee.Subscribe
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Immunosuppressants are chemical agents (such as pimecrolimus or tacrolimus) that suppresses the immune response. Pimecrolimus (Elidel) and Tacrolimus(Protopic) are known as calcineurin inhibitors (TCIs) acting on immunophilins. Tacrolimus is a fungal product (Streptomyces tsukubaensis) and a macrolide lactoneand acts by inhibiting calcineurin with trade names such as Prograf, Advagraf, Protopic, and others.
“The topical calcineurin inhibitors (TCIs) pimecrolimus and tacrolimus are approved for atopic dermatitis but have additional potential in other inflammatory skin diseases … whereas the response in rosacea and rosacea-like eruptions has been mixed.”
LEARN MORE (requires subscription)
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(1) Stop the brimonidine (Mirvaso) treatment and notify the physician who prescribed it since your physician may have some helpful treatment for you to consider. Sometimes physicians are helpful in situations like this. LEARN MORE (requires you join the RRDi)
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Brimonidine is an α2 adrenergic agonist. According to Wikipedia, "Brimonidine is indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is also the active ingredient of Combigan along with timolol maleate. In 2013, the FDA approved topical application of brimonidine 0.33% (Mirvaso - requires subscription to view post) for facial erythema or rosacea.
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"To date, oral and topical probiotics for the skin microbiome play an important role in treating inflammatory skin diseases, atopic dermatitis, acne, rosacea, wound healing, and skin cancer." [1]
"These results demonstrate that butyric acid (BA) in the metabolites of fermenting skin probiotic bacteria mediates FFaR2 to induce the synthesis of collagen through p-ERK activation. We hereby imply that metabolites from the probiotic S. epidermidis fermentation of CIN as a potential carbon source could restore impaired collagen in the dermal extracellular matrix (ECM), providing integrity and elasticity to skin."
"Butyric acid (from Ancient Greek: βούτῡρον, meaning "butter"), also known under the systematic name butanoic acid, is a straight-chain alkyl carboxylic acid with the chemical formula CH3CH2CH2CO2H. It is an oily, colorless liquid with an unpleasant odor. Isobutyric acid (2-methylpropanoic acid) is an isomer. Salts and esters of butyric acid are known as butyrates or butanoates. The acid does not occur widely in nature, but its esters are widespread. It is a common industrial chemical[7] and an important component in the mammalian gut." (bold added) Do You Have a Gut Feeling About Rosacea?
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Image - Wikipedia Commons
The Classic Butterfly of Rosacea and the T - Zone
In discussing rosacea the 'butterfly' or T - Zone usually comes up. To LEARN MORE requires a subscription as an active member.
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ElaineA has a recommended treatment for demodectic rosacea using Borax, epsom salt, glycerin and avocado oil. To Learn MORE (requires subscription)
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The RRDi is sponsoring free rosacea blogs so you can have your own private or public blog included when you join the RRDi. That way you can direct your friends to your own blog and discuss what you are doing to control your rosacea. These blogs are usually public but you may want your own private blog. You choose whether your blog is public or private. Example of a public blog.
If you want your own private rosacea blog here are the steps:
PRIVATE BLOG
The default blog is public so all you do is change it to private and only invite your friends to view your blog.
(1) To setup your blog you first need to be a member of the RRDi by registering.
(2) Go to Blogs and look for the CREATE A BLOG button:
(3) Look for the ONLY THE MEMBERS I CHOOSE CAN READ THIS BLOG radio button:
Then click continue to setup your blog. If you need assistance, use the Invision Community help center or use the RRDi support center (only available for members of the RRDi).
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Biologics image - stock.adobe.com"Over the coming years, the growth in the biologics market is projected to be rapid, reaching US $580.5 billion (approximately €513.5 billion) by 2026." [1]
What are the biologic treatments for rosacea? Answer (members only)
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Baumann Skin Types Bingo Card image courtesy of Wikimedia CommonsThe Baumann Skin Type Indicator (BSTI) is a phenotype "classification system [that] has been adopted by estheticians, dermatologists, consumers and retailers to match cosmeceutical ingredients and skin care products to specific skin types." [1]
End Notes
[1] Baumann Skin Type Indicator (BSTI) (members only) -
"Current studies have provided preliminary evidence that PDT is an efficient and safe therapy in treating rosacea. However, rigorous randomized control trials (RCTs) with a larger sample size and longer follow-up time are warranted to verify the certain curative effects of PDT in treating rosacea and explore the most appropriate treatment schedule." [1] Wouldn't it be incredible if a non profit for rosacea independent of the PDT industry sponsored a peer reviewed, double blinded, clinical study on this as recommended in the above paper.
To learn more in an investigative post, join the RRDi and subscribe.
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"In case of a lack of efficacy or in case of contraindications (e.g. pregnancy, children below 8 years), azithromycin or metronidazole are alternative systemic therapies."
"Topical azithromycin may represent an additional treatment for ocular rosacea, with a shorter duration of treatment and absence of gastrointestinal side effects as compared to systemic doxycycline."
Doxycycline Anecdotal Reports
in Guests
Posted
We have a number of doxycycline anecdotal reports for you to view. However, it requires a subscription plan to view.