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David A Jones, MD

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About David A Jones, MD

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  • Are you a rosacean?
  1. Foundations often try to have their small grants serve as "seed" money, the idea being that they fund a small project which can serve as preliminary data for a larger (often NIH) grant. This in theory can turn a $25k foundation grant into a $250k NIH infusion into research in that disease. So, the foundation medical/scientific advisory committees are not necessarily looking for grants which will result in a publication or a new treatment - they're looking for grant applications which will result in a larger grant application. NIH tends to fund things which have a very high probability of resulting in an incremental increase in basic science knowledge in a field, so that's what the foundations often seek to fund too - not new treatments, not "breakthroughs". David Jones, MD, PhD
  2. I see this occasionally, but it usually isn't a big complaint. I don't know of any great tricks for treating it other than usual treatments for facial rosacea. One interesting possibility with ear rosacea is that if it really is reasonably common, it could be a great source of skin biopsy material for research.
  3. Dr. Gallo has done some very interesting work in innate immunity, and this is no exception. Definitely warrants some follow-up and confirmatory studies. However, it's important not to confuse "associated finding" with "cause". There is no end to literature linking the latest inflammatory mediator with a clinical disease. They rarely hold up to the test of time as being truly significant. -David Jones
  4. Hi all, I'm back from vacation, but would like to add my 2 cents. I think the connection between diet and rosacea is very interesting, but I'd rather see grants exploring the basic pathophysiology of rosacea. It's true that studying diet may shed light on the mechanisms involved, but I think exploring diet would be a very indirect route to this, and very difficult. I'd rather see more directed basic immunology work.
  5. Thanks for the welcome. I'm afraid I'm as mystified as anyone as to the cause of rosacea. My only "pet theory" concerning rosacea is that there may be a significant autoimmune contribution, and I wouldn't mind seeing some research along those lines.
  6. Hello! I spend my time doing a mix of basic science type research and clinical dermatology. My research is related to the immune system as it affects skin disease and skin cancer. My clinical work is in general dermatology, and I see a fair bit of rosacea here among the Irish in Boston. Although I know more about basic science research and immunology, I'll happy to help try to find answers for any questions.
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