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Diamine Oxidase
Diamine Oxidase is one of the flushing avoidance treatments that some have used to prevent flushing.
Features diamine oxidase (DAO), the enzyme responsible for breaking down histamine
Breakd down food-derived HISTAMINE
Supports SKIN, RHINOCONJUNCTIVAL, & GASTROINTESTINAL among individuals with lower histamine tolerance
Enhances the Presence of Diamine Oxidase in the Digestive Tract
All Omnivits Formulas Meet or Exceed cGMP Quality Standards
Product description
Hist Diamine is a patented enzyme formula containing diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract. Endogenous and exogenous histamine must be broken down in order to maintain homeostasis and histamine balance. The enzyme diamine oxidase (DAO) degrades histamine by converting it from 2-(4-imidazolyl)-ethylamine to the inactive metabolite imidazole acetaldehyde. The active ingredient in Hist Diamine is porcine-derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine. In humans and other mammals, DAO is found in high concentrations in the gastrointestinal mucosa. Animal studies suggest that circulating DAO may be a marker for mucosal integrity and maturity. Certain drugs may affect histamine balance in the body by promoting histamine release or inhibiting DAO. Histamine tolerance may not be the same for everyone. Results of a double-blind, placebo-controlled crossover study suggest that tolerance to histamine can vary from individual to individual. Total body histamine load must be considered when evaluating histamine tolerance, and a balance between histamine and DAO appears to be crucial to maintaining skin, rhinoconjunctival, and gastrointestinal health. Genetic and environmental factors may interact to influence DAO expression. Ongoing research addresses the role that genetic variations may play in individual differences in DAO metabolism, and serum activity was significantly associated with seven single nucleotide variations within the DAO gene. Histamine tolerance may be reflected in detailed questionnaires, food intake logs, trial with low-histamine diet, and measurement of DAO and histamine. Hist Diamine does not manage or address antibody-related or IgE-related food allergies.
About Diamine Oxidase
Purchase. Omnivits Hist Diamine | Histamine Blocker | Diamine Oxidase Enzyme Formula with Vitamin C | 20,000 HDU of DAO | Histamine Intolerance | 60 Vegetarian Capsules
Diamine Oxidase is one of the flushing avoidance treatments that some have used to prevent flushing.
Features diamine oxidase (DAO), the enzyme responsible for breaking down histamine
Breakd down food-derived HISTAMINE
Supports SKIN, RHINOCONJUNCTIVAL, & GASTROINTESTINAL among individuals with lower histamine tolerance
Enhances the Presence of Diamine Oxidase in the Digestive Tract
All Omnivits Formulas Meet or Exceed cGMP Quality Standards
Product description
Hist Diamine is a patented enzyme formula containing diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract. Endogenous and exogenous histamine must be broken down in order to maintain homeostasis and histamine balance. The enzyme diamine oxidase (DAO) degrades histamine by converting it from 2-(4-imidazolyl)-ethylamine to the inactive metabolite imidazole acetaldehyde. The active ingredient in Hist Diamine is porcine-derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine. In humans and other mammals, DAO is found in high concentrations in the gastrointestinal mucosa. Animal studies suggest that circulating DAO may be a marker for mucosal integrity and maturity. Certain drugs may affect histamine balance in the body by promoting histamine release or inhibiting DAO. Histamine tolerance may not be the same for everyone. Results of a double-blind, placebo-controlled crossover study suggest that tolerance to histamine can vary from individual to individual. Total body histamine load must be considered when evaluating histamine tolerance, and a balance between histamine and DAO appears to be crucial to maintaining skin, rhinoconjunctival, and gastrointestinal health. Genetic and environmental factors may interact to influence DAO expression. Ongoing research addresses the role that genetic variations may play in individual differences in DAO metabolism, and serum activity was significantly associated with seven single nucleotide variations within the DAO gene. Histamine tolerance may be reflected in detailed questionnaires, food intake logs, trial with low-histamine diet, and measurement of DAO and histamine. Hist Diamine does not manage or address antibody-related or IgE-related food allergies.
