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  • Corporate Membership is open to the public and rosaceans are welcome

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    1. RRDi members must be polite and respectful to fellow members taking into consideration the individual fellow member's religious, ethical, and cultural values, as well as age, race and sex. The institute determines what is polite and respectful and may or may not give warnings for violating this rule. Removal from the membership is possible for violating this rule. It is a privilege to be a member of the RRDi and not a right.

    2. To be a legal corporate voting member a name, mailing address, two email addresses, and a statement of whether the member is a rosacean or not a rosacean is required. Non voting members are only required to provide a valid email address. 

    3. Members may not profit from the institute; however, any Medical Advisory Consultants (or Committee) member or any other member may be compensated for services rendered to the institute.

    4. Members who sell items or services for rosacea may comment on a treatment, product, book or service sold by the member when another member asks for information. However, the institute may at any time stop the discussion, delete the posts or ban the member at the sole discretion of the institute. Warnings may or may not be given to the member by the institute. Profiting from contacts of fellow members through the institute is not the purpose of this non profit institute. However, information is acceptable to post when asked and appropriate comments are allowed subject to the approval by the institute. The RRDi determines if the post is appropriate or not and you agree to this decision.

    5. Voting members should state if they have a diagnosis of rosacea from a physician and failure to discuss this may be grounds for dismissal as a member. The institute needs to know which voting members are rosaceans to determine the percentage of voting members who have a diagnosis of rosacea from a physician and which voting members are not rosacea sufferers. Non voting members are also required to state if they have a diagnosis of rosacea if another member inquires.  

    6. Privacy is of concern to the institute. Names, mailing and email addresses are not given out to the public or to fellow members by the institute. Your public profile is available to anyone to view but only shows your location, country, and whether you are a rosacean if you put data into these public profile boxes. Your personal profile like first and last name, etc., is never shown to the public and only RRDi staff members can view your personal profile. You agree to allow your public profile to be shown. Members should not release names, mailing or email addresses of fellow members if you are aware of the personal contact information of a fellow member without the consent of the fellow member. A Privacy Policy is available for the public. Members who donate to the institute will be listed with their name and the amount unless the donor requests anonymity. If you want to remain anonymous please let the institute know when you donate otherwise your name will be posted without any address, phone, or email address.

    7. Members will adhere, agree to and obey the Guidelines, Charter, Articles of Incorporation, the Bylaws, the Conflict of Interest Policy and these Rules of the Institute. Violation of any of these rules may be grounds for being removed as a corporate voting member or non voting member. You may view these documents by request or check the site index.

    8. A 'rosacean' is a rosacea sufferer. 'Institute' refers to the RRDi. RRDi refers to the Rosacea Research & Development Institute. You accept these terms.

    9. Anyone can join as a non voting member and post in the forum without providing any contact information other than a valid email address. 

       10.  The Rules of the Institute may be changed at any time at the sole discretion of the institute. 

     

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  • Posts

    • So how did you achieve remission?  What regimen treatment did you use?
    • Occupational Dermatoses Among Frontline Healthcare Workers During the COVID-19 Pandemic: A Cross-Sectional Survey. J Am Acad Dermatol. 2020 Sep 17;: Authors: Trepanowski N, Larson AR, Evers-Meltzer R PMID: 32950541 [PubMed - as supplied by publisher] {url} = URL to article Journal Pre-proof
    • Related Articles Paired Transcriptomic and Proteomic Analysis Implicates IL-1β in the Pathogenesis of Papulopustular Rosacea Explants. J Invest Dermatol. 2020 Sep 14;: Authors: Harden JL, Shih YH, Xu J, Li R, Rajendran D, Hofland H, Chang ALS Abstract Papulopustular rosacea (PPR) is a chronic inflammatory skin disease with limited treatment options. Although multiple pathways have been described to be upregulated in PPR, a mechanistic understanding of the key drivers and interaction between pathways in PPR pathology is lacking. In this study, we utilized PPR biopsy explants to integrate both differentially expressed genes (DEGs) and differently expressed proteins (DEPs) in paired non-lesional (NL) and lesional (LS) PPR tissue (n=5 patients). The results of this study identified 92 DEGs and 20 DEPs between paired PPR LS and NL explants. MAPK and TNF signaling pathways were the most significantly upregulated pathways in PPR LS tissue and aligned with DEPs identified in this study. Both MAPK and TNF signaling pathways highlighted IL-1β as a potential central mediator to PPR pathogenesis. In support of this, stimulation of NL explants with IL-1β resulted in a transcriptomic and proteomic profile similar to LS PPR. In this integrative transcriptomic and quantitative protein analysis, we identified several inflammatory genes, proteins, and pathways which may be contributing to PPR, as well as highlighted a potential role of IL-1β in driving inflammation in PPR. PMID: 32941918 [PubMed - as supplied by publisher] Full Text {url} = URL to article Interleukin 1 beta (IL-1β) is a cytokine.  Cytokines and Rosacea
    • Fluorescence-advanced videodermatoscopy characterization of demodex mites. A comparison with reflectance confocal microscopy. J Eur Acad Dermatol Venereol. 2020 Sep 14;: Authors: Fernandez-Nieto D, Segurado-Miravalles G, Gonzalez-Cantero A, Ortega-Quijano D, Jimenez-Cauhe J, Boixeda P Abstract Demodex mites (namely D. folliculorum and D. Brevis) are commonly considered commensals of human pilosebaceous units. However, they are thought to play a pathogenic role in several skin conditions, specially pityriasis folliculorum, rosacea, perioral dermatitis and hair folliculitis.1 Several studies report an increased density of demodex mites in patients with rosacea (papulopustular and erythematotelangiectatic forms. PMID: 32924177 [PubMed - as supplied by publisher] {url} = URL to article
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