Health Sci Rep. 2023 Sep 25;6(9):e1576. doi: 10.1002/hsr2.1576. eCollection 2023 Sep. ABSTRACT BACKGROUND AND AIM: Metabolic syndrome (MetS) is a well-known noncommunicable disease that plays a significant role in emerging other chronic disorders and following complications. MetS is also involved in the pathophysiology of numerous dermatological diseases. We aim to evaluate the association of MetS with the most prevalent dermatological diseases. METHODS: A systematic search was carried out on PubMed, Science Direct, Web of Science, Cochrane, as well as the Google Scholar search engine. Only English case-control studies regarding MetS and any skin disease from the beginning of 2010 up to November 15, 2022, were selected. The study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). RESULTS: A total of 37 studies (13,830 participants) met the inclusion criteria. According to our result, patients with psoriasis, hidradenitis suppurativa (HS), vitiligo, androgenetic alopecia (AGA), and lichen planus (LP) have a higher chance of having MetS compared to the general population. Furthermore, people with seborrheic dermatitis (SED) and rosacea are more prone to insulin resistance, high blood pressure (BP), and higher blood lipids. After pooling data, the meta-analysis revealed a significant association between MetS and skin diseases (pooled odds ratio [OR]: 3.28, 95% confidence interval: 2.62-4.10). Concerning the type of disease, MetS has been correlated with AGA (OR: 11.86), HS (OR: 4.46), LP (OR: 3.79), and SED (OR: 2.45). Psoriasis also showed a significant association but with high heterogeneity (OR: 2.89). Moreover, skin diseases and MetS are strongly associated in Spain (OR: 5.25) and Thailand (OR: 11.86). Regarding the metaregression model, the effect size was reduced with increasing age (OR: 0.965), while the size increased with AGA (OR: 3.064). CONCLUSIONS: MetS is closely associated with skin complications. Dermatologists and other multidisciplinary teams should be cautious while treating these patients to prevent severe complications resulting from MetS. PMID:37752973 | PMC:PMC10519158 | DOI:10.1002/hsr2.1576 {url} = URL to article

Skin Res Technol. 2023 Sep;29(9):e13411. doi: 10.1111/srt.13411. NO ABSTRACT PMID:37753697 | DOI:10.1111/srt.13411 {url} = URL to article

JMIR Dermatol. 2023 Sep 25;6:e49070. doi: 10.2196/49070. ABSTRACT Case reports serve many functions in the medical literature. We explore patient demographics in case reports for common inflammatory skin diseases. PMID:37747769 | DOI:10.2196/49070 {url} = URL to article

Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2023 Aug;31(Special Issue 1):881-886. doi: 10.32687/0869-866X-2023-31-s1-881-886. ABSTRACT Currently, there is an urgent need for global research to develop a modern comprehensive study of rosacea, including its pathogenesis, risk factors, association of rosacea subtypes with concomitant diseases. The most relevant research studies the role of immunity and microorganisms in the pathogenesis of rosacea. To elucidate the features of the comorbidity of rosacea and somatic diseases, studies in various populations with detailed clinical data and a longer follow-up period are important. At the same time, it is important to understand the relationship between the severity and severity of various clinical symptoms of rosacea, the mechanisms that regulate the progression of the process, the combination of rosacea subtypes and the course of the disease in association with other forms of pathological disorders. PMID:37742268 | DOI:10.32687/0869-866X-2023-31-s1-881-886 {url} = URL to article

Cureus. 2023 Sep 17;15(9):e45391. doi: 10.7759/cureus.45391. eCollection 2023 Sep. ABSTRACT Granulomatous rosacea is a chronic inflammatory skin disease. We present the case of a 30-year-old woman with a three-month history of erythematous monomorphic papules and nodules on the cheeks and forehead. Histopathological examinations revealed tuberculoid granulomas with multinucleated giant cells. Granulomatous rosacea should be differentiated from other similar granulomatous skin diseases such as cutaneous sarcoidosis and Lupus miliaris disseminates faciei. PMID:37724096 | PMC:PMC10505268 | DOI:10.7759/cureus.45391 {url} = URL to article