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  1. Occupational Dermatoses Among Frontline Healthcare Workers During the COVID-19 Pandemic: A Cross-Sectional Survey. J Am Acad Dermatol. 2020 Sep 17;: Authors: Trepanowski N, Larson AR, Evers-Meltzer R PMID: 32950541 [PubMed - as supplied by publisher] {url} = URL to article Journal Pre-proof
  2. Related Articles Paired Transcriptomic and Proteomic Analysis Implicates IL-1β in the Pathogenesis of Papulopustular Rosacea Explants. J Invest Dermatol. 2020 Sep 14;: Authors: Harden JL, Shih YH, Xu J, Li R, Rajendran D, Hofland H, Chang ALS Abstract Papulopustular rosacea (PPR) is a chronic inflammatory skin disease with limited treatment options. Although multiple pathways have been described to be upregulated in PPR, a mechanistic understanding of the key drivers and interaction between pathways in PPR pathology is lacking. In this study, we utilized PPR biopsy exp
  3. Fluorescence-advanced videodermatoscopy characterization of demodex mites. A comparison with reflectance confocal microscopy. J Eur Acad Dermatol Venereol. 2020 Sep 14;: Authors: Fernandez-Nieto D, Segurado-Miravalles G, Gonzalez-Cantero A, Ortega-Quijano D, Jimenez-Cauhe J, Boixeda P Abstract Demodex mites (namely D. folliculorum and D. Brevis) are commonly considered commensals of human pilosebaceous units. However, they are thought to play a pathogenic role in several skin conditions, specially pityriasis folliculorum, rosacea, perioral dermati
  4. Ocular rosacea. Curr Opin Ophthalmol. 2020 Sep 08;: Authors: Redd TK, Seitzman GD Abstract PURPOSE OF REVIEW: To revisit ocular rosacea as an underappreciated condition which can cause permanent blindness if inadequately treated, and to review data supporting improved diagnostic and treatment strategies. RECENT FINDINGS: Ocular rosacea has an underrecognized prevalence in children and individuals with darker skin tone. Rosacea has several associations with other significant systemic diseases. Variations in local and systemic microbiome, i
  5. Related ArticlesDiagnostic and Therapeutic Challenges. Retina. 2019 Dec;39(12):2419-2422 Authors: Zago LA, Lima LH, Zett C, Sato M, Shiokawa N, Bhatt N PMID: 30461539 [PubMed - indexed for MEDLINE] {url} = URL to article
  6. Ocular Symptoms of Rosacea. Cesk Slov Oftalmol. 2020;75(6):329-333 Authors: Beran D, Stepanov A, Studnička J, Jirásková N Abstract The authors present case reports of two women, who were hospitalized in Department of Ophthalmology, University hospital Hradec Králové for ocular symptoms of rosacea. In the beginning there were relatively severe objective findings in the anterior segment of the eye in both cases - significant cornea graying with superficial and deep cornea vascularization in both eyes. On faces of both patients there were more or les
  7. Microbiota in Rosacea. Am J Clin Dermatol. 2020 Sep 10;: Authors: Kim HS Abstract Rosacea is a complex facial skin condition associated with abnormal inflammation and vascular dysfunction. Next to the known trigger factors, the role of microbiota in the development and aggravation of rosacea continues to raise interest. Demodex folliculorum mites, Helicobacter pylori, Staphylococcus epidermidis, Chlamydia pneumoniae, and the Demodex-associated bacterium, Bacillus oleronius are microbes that have been linked with rosacea. However, the results of st
  8. Severe phymatous rosacea of the nose, cheeks, and chin treated with hydrosurgery. Cutis. 2020 Jul;106(1):37-39 Authors: Bittar JM, Kovach SJ, Ditre CM Abstract Phymatous rosacea is a rare and severe form of rosacea that manifests as disfiguring soft-tissue hypertrophy and sebaceous gland hyperplasia and fibrosis. Most cases are surgically treated; surgical modalities vary, however, ranging from cryosurgery to conventional excision, and consensus guidelines for surgical management do not exist. The Versajet II Hydrosurgery System (Smith-Nephew) is
  9. Related ArticlesSevere rhinophyma treated by shave excision and electrocautery. BMJ Case Rep. 2020 Jan 13;13(1): Authors: Gupta M, Singh G, Gupta M Abstract Rhinophyma is a rare disease, causing disfiguring soft-tissue hypertrophy of the nose. Various medical and surgical treatment modalities have been tried, with limited success. We report a case of a 76-year-old man, where shave excision of the rhinophymatous tissue was done with satisfactory cosmetic outcome. PMID: 31937630 [PubMed - indexed for MEDLINE] {url} = URL to article
  10. Related ArticlesHormonal Contraceptives and Dermatology. Am J Clin Dermatol. 2020 Sep 07;: Authors: Williams NM, Randolph M, Rajabi-Estarabadi A, Keri J, Tosti A Abstract Hormones play a significant role in normal skin physiology and many dermatologic conditions. As contraceptives and hormonal therapies continue to advance and increase in popularity, it is important for dermatologists to understand their mechanisms and dermatologic effects given the intricate interplay between hormones and the skin. This article reviews the dermatologic effects, b
  11. Related ArticlesTLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis. J Dermatol Sci. 2020 Aug 29;: Authors: Shimada-Omori R, Yamasaki K, Koike S, Yamauchi T, Aiba S Abstract BACKGROUND: While most skin diseases benefit from topical steroids, rosacea symptoms are exacerbated by topical steroids. In the rosacea pathogenesis, abnormal innate immune mechanisms including overexpression of the Toll-like receptor (TLR) have been proposed. However, the links b
  12. Related Articles Efficacy and tolerability of a cream containing modified glutathione (GSH-C4), beta-Glycyrrhetic and azelaic acids in mild-to-moderate rosacea: A pilot, assessor-blinded, VISIA and ANTERA 3-D analysis, two-center study (The "Rosazel" Trial). J Cosmet Dermatol. 2020 Sep 03;: Authors: Dall'Oglio F, Puviani M, Milani M, Micali G Abstract INTRODUCTION: Rosacea is a very common, chronic inflammatory disease characterized by flushing, erythema and inflammatory lesions. Increased oxidative stress plays a relevant pathogenetic role in Rosacea. Intracellular Gl
  13. Related ArticlesA case of primary cutaneous marginal zone lymphoma presenting with rosacea-like eruption. JAAD Case Rep. 2020 Sep;6(9):902-904 Authors: Agnihotri T, Adotama P, Kalowitz-Bieber A, Stokar E, Meehan SA, Latkowski JA PMID: 32875041 [PubMed] {url} = URL to article
  14. Related Articles Morbihan Disease - An Old and Rare Entity Still Difficult to Treat. Acta Dermatovenerol Croat. 2020 Aug;28(2):118-119 Authors: Jerković Gulin S, Ljubojević Hadžavdić S Abstract Morbihan disease (MD), also known as Morbihan syndrome, "solid persistent facial edema and erythema", "rosacea lymphedema", and "solid facial edema in acne", is a rare and often unrecognizable entity, that presents with a slow occurrence of persistent lymphoedema of the upper two-thirds of the face (1,2). A 30-year-old woman presented to our Department with persistent, asymptoma
  15. Related Articles Surgical treatment of rhinophyma using an ordinary bur. Arch Craniofac Surg. 2020 Aug;21(4):264-267 Authors: Kang JK, Lee JS, Choi JH, Shin MS, Yun BM Abstract Rhinophyma is a painless benign tumor of the skin of the nose. It is the most severe form of rosacea. Rhinophyma is particularly rare among Asians. It can be treated with surgical resection using various methods, including scalpel excision, dermabrasion, cryosurgery, argon laser, carbon dioxide laser, and electrocautery. However, the gold standard treatment of rhinophyma remains unknown. In the
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