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  1. Related ArticlesRosacea in skin of color: A comprehensive review. Indian J Dermatol Venereol Leprol. 2020 Oct 27;: Authors: Sarkar R, Podder I, Jagadeesan S Abstract Rosacea is a relatively common inflammatory dermatosis in persons with fair skin. It is uncommonly reported in people with skin of color (darker skin tone; Fitzpatrick skin types IV, V or VI). Apart from reduced incidence, underreporting due to decreased awareness might also be a probable explanation. Rosacea commonly presents with telangiectasias and persistent facial erythema on the
  2. Related Articles[A systematic review and current recommendation for treatment of rhinophyma]. Laryngorhinootologie. 2020 Nov;99(11):772-778 Authors: Huseynov J, Mozet C Abstract Rhinophyma is a benign disease involving the skin of the nose, which is characterized by skin thickening and hypertrophy of the sebaceous glands and connective tissue. It occurs predominantly by Caucasians in their fifth to seventh life decades and is 12-30 times more likely to affect males. The etiology and pathogenesis of Rhinophyma remains unclear, however it is general
  3. Related ArticlesRosacea and its comorbidities: Should be emphasized but should not be overemphasized. J Cosmet Dermatol. 2020 Oct 27;: Authors: Zhang H, Tang K, Wang Y, Fang R, Sun Q PMID: 33111478 [PubMed - as supplied by publisher] {url} = URL to article
  4. Related ArticlesWillingness-to-Pay and Benefit-Cost Analysis of IPL for Rosacea Treatment: A Cross-Sectional Study in China. Patient Prefer Adherence. 2020;14:1843-1852 Authors: Deng Q, Zhang SP, Deng YX, Liu FF, Shi W, Xie HF, Xiao Y, Huang YX, Li J Abstract Background: Intense pulsed light (IPL), as a therapeutic approach for rosacea, had advantage in removing erythema and telangiectasia and was gradually accepted by rosacea patients, but there have been few studies on economic evaluation of this therapy. Purpose: This study aimed to de
  5. Related ArticlesA Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin. Clin Cosmet Investig Dermatol. 2020;13:751-758 Authors: Berardesca E, Bonfigli A, Cribier B, Flament F, Vicic M, Kerob D, Tan J Abstract Objective: This study assessed the efficacy and tolerability of M89 in patients with rosacea associated with erythema and sensitive skin. Methods: Intra-individual study in a split-face design comparing after 30 d
  6. Comments on "The Decrease of Demodex Density After Nd:YAG Laser Application for Facial Telengiactasias: A Case Report". Dermatol Ther. 2020 Oct 27;: Authors: Clatici VG, Voicu C, Barinova E, Tatu AL PMID: 33107672 [PubMed - as supplied by publisher] {url} = URL to article
  7. Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide. Front Immunol. 2020;11:559589 Authors: Dondalska A, Rönnberg E, Ma H, Pålsson SA, Magnusdottir E, Gao T, Adam L, Lerner EA, Nilsson G, Lagerström M, Spetz AL Abstract Numerous inflammatory skin disorders display a high prevalence of itch. The Mas-related G protein coupled receptor X2 (MRGPRX2) has been shown to modulate itch by inducing non-IgE-mediated mast cell degranulation and the release of endogenous inducers of pruritus. Various
  8. The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea? Dermatol Ther (Heidelb). 2020 Oct 23;: Authors: Forton FMN Abstract Rosacea is a common facial dermatosis but its definition and classification are still unclear, especially in terms of its links with demodicosis. Triggers of rosacea (ultraviolet light, heat, spicy foods, alcohol, stress, microbes) are currently considered to induce a cascading innate and then adaptive immune response that gets out of control. Recent histological and biochemical studies
  9. "Fake news" in dermatology. Results from an observational, cross-sectional study. Int J Dermatol. 2020 Oct 23;: Authors: Iglesias-Puzas Á, Conde-Taboada A, Aranegui-Arteaga B, López-Bran E Abstract BACKGROUND: Social networks have become a means for disseminating information on health-related matters. OBJECTIVE: Describe the characteristics and analyze the accuracy of the dermatology content that is most often shared on the most popular social networks. MATERIALS AND METHODS: The content most often shared on social networks (Facebook, Pinterest, Twitter, and Reddit) betwee
  10. The Pro-Differentiation Effect of Doxycycline on Human SZ95 Sebocytes. Dermatology. 2020 Oct 22;:1-5 Authors: Zouboulis CC, Ní Raghallaigh S, Schmitz G, Powell FC Abstract BACKGROUND: Despite their widespread clinical use in both acne vulgaris and rosacea, the effects of tetracyclines on sebocytes have not been investigated until now. Sebaceous glands are central to the pathogenesis of acne and may be important in the development of rosacea. OBJECTIVE: The aim of this study was to assess the effects of doxycycline on the immortalized SZ95
  11. Granulomatous Rosacea in Korean Patients: Diagnosis Based on Combining Clinical and Histological Findings. Dermatology. 2020 Oct 22;:1-5 Authors: Yang JH, Cho SI, Suh DH Abstract BACKGROUND: Granulomatous rosacea (GR) is a rare inflammatory skin disease, which is considered a variant of rosacea, apart from other types of rosacea. OBJECTIVE: This study aimed to summarize the characteristics of Korean patients diagnosed with GR by combining clinical and histological findings. METHODS: Fifteen cases, both clinically and histological
  12. Systemic Comorbidities in Korean Patients with Rosacea: Results from a Multi-Institutional Case-Control Study. J Clin Med. 2020 Oct 17;9(10): Authors: Woo YR, Kim HS, Lee SH, Ju HJ, Bae JM, Cho SH, Lee JD Abstract Recent evidence links rosacea to systemic disease, but there are not enough methodologic studies addressing this association in Asians. Our aim was to identify rosacea comorbidities in Koreans and establish a reference database. A multi-center, case-control study was performed where a total of 12,936 rosacea patients and 12,936 age- and
  13. Related ArticlesA warning against associating doxycycline with isotretinoin. Arq Bras Oftalmol. 2020 08;83(4):350 Authors: Costa AXD, Benchimol GL, Reis TF PMID: 32756781 [PubMed - indexed for MEDLINE] {url} = URL to article
  14. Deep Learning for Diagnostic Binary Classification of Multiple-Lesion Skin Diseases. Front Med (Lausanne). 2020;7:574329 Authors: Thomsen K, Christensen AL, Iversen L, Lomholt HB, Winther O Abstract Background: Diagnosis of skin diseases is often challenging and computer-aided diagnostic tools are urgently needed to underpin decision making. Objective: To develop a convolutional neural network model to classify clinically relevant selected multiple-lesion skin diseases, this in accordance to the STARD guidelines. Methods: This was an image-based r
  15. Cardiovascular Risk and Comorbidities in Patients with Rosacea: A Systematic Review and Meta-analysis. Acta Derm Venereol. 2020 Oct 19;: Authors: Tsai TY, Chiang YY, Huang YC Abstract The association between rosacea and cardiovascular disease remains controversial. A systematic review and meta-analysis of the literature, from inception to 15 February 2020, was performed to compare cardiovascular risk and comorbidities in individuals with and without rosacea. Twelve studies, involving 40,752 patients with rosacea, were included. Compared with contr
  16. Related ArticlesPublication of national dermatology guidelines as a Research Letter in the BJD: can less ever be enough? Br J Dermatol. 2020 06;182(6):1319-1320 Authors: van Zuuren EJ, Arents BWM, Flohr C, Ingram JR PMID: 32476154 [PubMed - indexed for MEDLINE] {url} = URL to article
  17. Holistic care of patients with rosacea. J Cosmet Dermatol. 2020 Oct 14;: Authors: Searle T, Al-Niaimi F, Ali FR Abstract We thank the authors for their commentary on our article Rosacea and the Cardiovascular System.1 The authors discuss the risk of "excessive health examination". Whilst we do not advocate over investigation or over treatment of any patient, the association between cardiovascular disease and rosacea is evident2,3 and any dermatologist or clinician treating patients with rosacea should be aware of these associations as well as othe
  18. Acne in the first three decades of life: An update of a disorder with profound implications for all decades of life. Dis Mon. 2020 Oct 08;:101103 Authors: Greydanus DE, Azmeh R, Cabral MD, Dickson CA, Patel DR Abstract Acne vulgaris is a chronic, inflammatory, skin condition that involves the pilosebaceous follicles and is influenced by a variety of factors including genetics, androgen-stimulation of sebaceous glands with abnormal keratinization, colonization with Cutibacterium acnes (previously called Propionibacterium acnes), and pathological im
  19. Brazilian Society of Dermatology consensus on the use of oral isotretinoin in dermatology. An Bras Dermatol. 2020 Oct 03;: Authors: Bagatin E, Costa CS, Rocha MADD, Picosse FR, Kamamoto CSL, Pirmez R, Ianhez M, Miot HA Abstract BACKGROUND: Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple mechanisms of action and highly effective in the treatment of acne, despite common adverse events, manageable and dose-dependent. Dose-independent teratogenicity is the most serious. Therefore, off-label prescriptions require strict crit
  20. Dermoscopy in Monitoring and Predicting Therapeutic Response in General Dermatology (Non-Tumoral Dermatoses): An Up-To-Date Overview. Dermatol Ther (Heidelb). 2020 Oct 08;: Authors: Errichetti E Abstract Besides the well-known use in supporting the non-invasive diagnosis of non-tumoral dermatoses (general dermatology), dermoscopy has been shown to be a promising tool also in predicting and monitoring therapeutic outcomes of such conditions, with the consequent improvement/optimization of their treatment. In the present paper, we sought to provide an up-to-date overview on the
  21. [Manifestaciones clínicas y evolución a largo plazo de tres casos de rosácea ocular atendidos en un hospital de alta especialidad del sureste de México]. Biomedica. 2020 Sep 01;40(3):448-455 Authors: Xacur-García F, Díaz-Novelo R, Herrera-David L, Moreno-Arjona P, Méndez-Domínguez N Abstract La rosácea es una alteración cutánea crónica que se ha asociado con factores etiológicos inespecíficos y diversas manifestaciones sistémicas. La rosácea cutánea suele evolucionar a rosácea ocular del 6 al 72 % de los pacientes. Al no existir criterios específi
  22. Rosacea in acne vulgaris patients: subtype distribution and triggers assessment--a cross-sectional study. J Cosmet Dermatol. 2020 Oct 06;: Authors: Chen H, Lai W, Zheng Y Abstract BACKGROUND: Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of this two diseases co-occurrence is remain unclear. This study aims to investigate the classification and severity of female patients combining with acne and rosacea. METHODS: Female Patients with facial acn
  23. Rationale for Use of Combination Therapy in Rosacea. J Drugs Dermatol. 2020 Oct 01;19(10):929-934 Authors: Stein Gold L, Baldwin H, Harper JC Abstract BACKGROUND: Rosacea is a chronic skin condition characterized by primary and secondary manifestations affecting the centrofacial skin. The primary diagnostic phenotypes for rosacea are fixed centrofacial erythema with periodic intensification, and phymatous changes. Major phenotypes, including papules and pustules, flushing, telangiectasia, and ocular manifestations, may occur concomitantly or indep
  24. Association between Demodex folliculorum and Metabolic Syndrome. J Cosmet Dermatol. 2020 Oct 05;: Authors: Toka Özer T, Akyürek Ö, Durmaz S Abstract BACKGROUND: Demodex folliculorum mite infestation is associated with many diseases such as rosacea, pityriasis found with acne vulgaris, and blepharitis. AIM: In this research, the aim of this study was to investigate an association between patients who have metabolic syndrome and presence of Demodex folliculorum. PATIENTS/METHODS: This research was planned prospectively as a case-control study. Fifty cases who have metabolic
  25. Diagnostic and Management Considerations for 'Maskne' in the Era of COVID-19. J Am Acad Dermatol. 2020 Oct 01;: Authors: Teo WL PMID: 33011321 [PubMed - as supplied by publisher] {url} = URL to article
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