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Topical rosacea therapy: the importance of vehicles for efficacy, tolerability and compliance. J Drugs Dermatol. 2011 Jun 1;10(6):627-33 Authors: Jackson JM, Pelle M Many topical medications are available for the treatment of papulopustular rosacea. While treatments contain metronidazole, azelaic acid, or sodium sulfacetamide-sulfur as the active ingredient, the composition of the vehicle formulations varies widely. These vehicles come in gels, creams, lotions and foams; some ingredients are common to many vehicles, while some vehicles contain unique ingredients designed to optimize skin penetration and delivery of the active drug to its target. Vehicles can also influence tolerability, which is always a concern in patients with heightened skin sensitivity, and compliance, which is typically lower for topical treatments than oral treatments. Ideally, the vehicle of any rosacea treatment should enhance drug delivery, be nonirritating and be easy to use. Ingredients that help repair barrier function are also desirable. This review will focus on the key components of the vehicles from the most commonly used topical therapies for papulopustular rosacea and how vehicle formulations influence the delivery of active ingredient, skin barrier repair, tolerability and compliance. J Drugs Dermatol. 2011;10(6):627-633. PMID: 21637903 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21637903&dopt=Abstract = URL to article

Prevalence of skin lesions and need for treatment in a cohort of 90,880 workers. Br J Dermatol. 2011 May 28; Authors: Augustin M, Herberger K, Hintzen S, Heigel H, Franzke N, Schäfer I Background:  Healthcare planning requires robust data on the prevalence and need for care of dermatological diseases. To date, no systematic data in population-based samples are available for Germany. Aim:  Determination of the prevalence of skin lesions and of the need for care based on dermatological exams in working adults in Germany. Methodology:  From 2004 to 2009, workers aged between 16 and 70 years from different branches of industry throughout Germany underwent a single dermatological whole-body status on the occasion of company screening for skin cancer. The data were recorded electronically and evaluated descriptively. In addition to the clinical findings, case-history data on previous skin diseases were documented and the need for further clarification or treatment was determined on the basis of the dermatologist's assessment. Results:  Data from n = 90,880 persons from a total of 312 companies were evaluated. Of the pigmented skin lesions, dermal naevi were found in 25.1% of the cohort, 16.7% of whom displayed more than 40 each. The most frequent inflammatory skin diseases were acne vulgaris (3.9%), psoriasis (2.0%), rosacea (2.3%) and atopic dermatitis (1.4%). Examination of the case histories showed that the most frequent condition was allergic sensitisation (41.1%); of these, pollen accounted for the biggest group (21.4%), followed by contact allergens (8.0%). Allergic rhinitis was the most frequent allergic disease (25.5%). In total, 26.8% of the cohort exhibited a dermatological finding in need of treatment or further clarification. Conclusion:  Dermatological lesions and diseases requiring clarification are frequent and indicate a high demand for treatment in the adult population. PMID: 21623753 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21623753&dopt=Abstract = URL to article

In vitro antimicrobial, anthelmintic and cyclooxygenase-inhibitory activities and phytochemical analysis of Leucosidea sericea. J Ethnopharmacol. 2010 Aug 19;131(1):22-7 Authors: Aremu AO, Fawole OA, Chukwujekwu JC, Light ME, Finnie JF, Van Staden J Leucosidea sericea is used as a vermifuge and in the treatment of ophthalmia by various tribes in southern African countries. PMID: 20542105 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=20542105&dopt=Abstract = URL to article

Alcohol and skin disorders: with a focus on psoriasis. Skin Therapy Lett. 2011 Apr;16(4):5-7 Authors: Kazakevich N, Moody MN, Landau JM, Goldberg LH Alcohol is a serious cause of morbidity and mortality in our society and is implicated in multiple health conditions, including hepatic failure, neurological damage, hematological disorders, and nutritional deficiencies, to name a few. Although alcohol induced cutaneous abnormalities can also cause significant morbidity, they tend to be overshadowed by the other disease states associated with alcohol use. In addition to the cutaneous stigmata linked to chronic alcoholic liver disease, alcohol can directly cause or exacerbate several skin conditions. In particular, alcohol misuse is implicated in the development of psoriasis and discoid eczema, as well as confers increased susceptibility to skin and systemic infections. Alcohol misuse might also exacerbate rosacea, porphyria cutanea tarda, and post adolescent acne. Herein, we review the evidence concerning the influences of alcohol in skin conditions with a focus on psoriasis. PMID: 21611681 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21611681&dopt=Abstract = URL to article

Miliary and agminated-type primary cutaneous follicle center lymphoma: Report of 18 cases. J Am Acad Dermatol. 2011 May 21; Authors: Massone C, Fink-Puches R, Laimer M, Rütten A, Vale E, Cerroni L BACKGROUND: Primary cutaneous follicle center lymphoma (PCFCL) presents usually with reddish nodules, plaques, and tumors on the head and neck area, particularly the scalp, and on the back. OBJECTIVE: We sought to describe a peculiar clinical variant of PCFCL. METHODS: We report a series of 18 patients (male:female = 7:11; median age 52 years; mean age 50.8 years; age range 27-75 years) with a clinical variant of PCFCL characterized clinically by multiple, miliary, or agminated papules predominantly on the head and neck. RESULTS: All patients presented with multiple erythematous, firm papules arranged in a manner that resembled millet seeds or collected together in small clusters. Lesions were located on the entire face in one patient (5.6%), the forehead in 8 (44.4%), the cheeks in 3 (16.7%), the preauricular region in two (11.1%), and multiple regions on the head and neck area in 3 (16.7%). The last patient had miliary papules on the entire face, back, upper aspect of arms, and scattered on the front of the chest. The initial diagnosis was never cutaneous lymphoma, and all patients had been treated unsuccessfully for different skin conditions including mainly rosacea, lupus miliaris disseminatus faciei, and persistent arthropod bite reaction. Microscopic examination confirmed the diagnosis of PCFCL in all patients. LIMITATIONS: Small number of cases and retrospective study are limitations. CONCLUSIONS: This peculiar clinical presentation of PCFCL is unusual and represents a pitfall in the clinical diagnosis. Dermatologists should be aware of this variant of PCFCL so as to treat patients timely and properly. PMID: 21601947 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21601947&dopt=Abstract = URL to article

[immune reconstitution inflammatory syndrome associated with eosinophilic pustular folliculitis in an HIV-infected patient]. Med Mal Infect. 2011 Jan;41(1):49-50 Authors: Springinsfeld G, Roth B, Martinot M, Tortel MC, Batard ML PMID: 21050684 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21050684&dopt=Abstract = URL to article

Steroid-induced rosacea: a clinical study of 200 patients. Indian J Dermatol. 2011 Jan;56(1):30-2 Authors: Bhat YJ, Manzoor S, Qayoom S Topical corticosteroids were first introduced for use in 1951. Since then uncontrolled use (abuse) has caused many different reactions resembling rosacea - steroid dermatitis or iatrosacea. Multiple pathways including rebound vasodilatation and proinflammatory cytokine release have been proposed as the mechanism for such reactions. PMID: 21572787 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21572787&dopt=Abstract = URL to article

Cleansers and their role in various dermatological disorders. Indian J Dermatol. 2011 Jan;56(1):2-6 Authors: Mukhopadhyay P The art of cleansing has progressed immensely over several thousand years from simply scraping the skin to an exercise in relaxation and improvement in the skin's health and appearance in the present day. Soaps - the basic cleansing agent has also undergone a sea change in its evolution with many variants and newer constituents being incorporated into it. In dermatological disorders like acne, rosacea, atopic dermatitis, photoaging, 'sensitive skin', occupational dermatosis cleansers may have a beneficial role along with other therapeutic measures. With the advent of aesthetic dermatology, the act of cleansing and the use of various cleansing agents prior to aesthetic procedures has also assumed significance. PMID: 21572782 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21572782&dopt=Abstract = URL to article

Rosacea: pathogenesis and therapy. G Ital Dermatol Venereol. 2011 Jun;146(3):235-42 Authors: Webster GF Rosacea is a chronic facial inflammatory disease. The pathogenesis, diagnosis and treatment are reviewed. PMID: 21566553 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21566553&dopt=Abstract = URL to article

New, relevant information and innovative interventions in the management of acne. G Ital Dermatol Venereol. 2011 Jun;146(3):197-210 Authors: Danby FW The recent innovative interventions in the acnes (acne vulgaris, acne rosacea and acne inversa) have not occurred in their management; rather the major changes are occurring in how the disorders and the individual lesions are seen to originate and develop. To finalize the optimal management of each of the acnes will ultimately require that every step in the aetiopathogenesis described and postulated here will need to be tested, validated, and then appropriately countered with environmental and lifestyle adjustments that will lead ultimately to prevention of 'the blight of youth' and its variants. PMID: 21566550 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21566550&dopt=Abstract = URL to article

A Case of Acne Fulminans in a Patient with Ulcerative Colitis Successfully Treated with Prednisolone and Diaminodiphenylsulfone: A Literature Review of Acne Fulminans, Rosacea Fulminans and Neutrophilic Dermatoses Occurring in the Setting of Inflammatory Bowel Disease. Dermatology. 2011 Apr 30; Authors: Wakabayashi M, Fujimoto N, Uenishi T, Danno K, Tanaka T A 19-year-old Japanese man had been treated for ulcerative colitis for 2 years. He was admitted to our hospital with nodulocystic inflammatory papules and pustules on his face and chest, high-grade fever, arthralgia and general malaise. A biopsy specimen from a pustule showed prominent infiltration of neutrophils in the epidermis and dermis, particularly around hair follicles. We made a diagnosis of acne fulminans. The systemic administration of prednisolone at 30 mg daily for 1 week immediately improved his skin lesions and other symptoms; however, during tapering of prednisolone at 20 mg daily, skin lesions flared up. The addition of oral diaminodiphenylsulfone improved the skin lesions. Although there have been a few reports of acne fulminans associated with Crohn's disease, this is the first case report of acne fulminans in a patient with ulcerative colitis. It is noteworthy that the addition of diaminodiphenylsulfone was effective for treating the relapse of acne fulminans in this case. PMID: 21540556 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21540556&dopt=Abstract = URL to article

Oral azithromycin for treatment of intractable rosacea. J Korean Med Sci. 2011 May;26(5):694-6 Authors: Kim JH, Oh YS, Choi EH Rosacea is a common chronic cutaneous disorder that primarily occurs on the convex surfaces of the central face and is often characterized by exacerbations and remissions. A case of a 52-yr-old woman visited our clinic in February 2008 complaining typical features of rosacea including multiple pinhead to rice-sized erythematous papules. We applied various conventional treatments including topical benzoyl peroxide and metronidazole as well as oral metronidazole, isotretinoin, and doxycycline. The lesions were not controlled but were rather aggravated by complications from these treatments. Therefore, we prescribed oral azithromycin, which has anti-inflammatory effects and reduces reactive oxygen species. Ten weeks after the administration of oral azithromycin, 500 mg per day for 2 weeks, the lesions had mostly disappeared and no specific side effects related to the azithromycin were noted. Oral azithromycin dosing 500 mg/day for 2 weeks is effective for treatment of intractable rosacea. PMID: 21532865 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21532865&dopt=Abstract = URL to article

A periocular nodule in a child. Clin Exp Dermatol. 2011 Jan;36(1):105-6 Authors: Al Dhaybi R, McCuaig C, Kokta V PMID: 21143516 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21143516&dopt=Abstract = URL to article

Impact of vitamin D3 on cutaneous immunity and antimicrobial peptide expression. Dermatoendocrinol. 2011 Jan;3(1):18-22 Authors: Antal AS, Dombrowski Y, Koglin S, Ruzicka T, Schauber J Antimicrobial peptides (AMPs) are effectors of cutaneous innate immunity and protect primarily against microbial infections. An array of AMPs can be found in and on the skin. Those include peptides that were first discovered for their antimicrobial properties but also proteins with antimicrobial activity first characterized for their activity as chemokines, enzymes, enzyme inhibitors and neuropeptides. Cathelicidins were among the first families of AMPs discovered in skin. They are now known to exert a dual role in innate immune defense: they have direct antimicrobial activity and will also initiate a host cellular response resulting in cytokine release, inflammation and angiogenesis. Altered cathelicidin expression and function was observed in several common inflammatory skin diseases such as atopic dermatitis, rosacea and psoriasis. Until recently the molecular mechanisms underlying cathelicidin regulation were not known. Lately, vitamin D3 was identified as the major regulator of cathelicidin expression and entered the spotlight as an immune modulator with impact on both, innate and adaptive immunity. Therapies targeting vitamin D3 signalling may provide novel approaches for the treatment of infectious and inflammatory skin diseases by affecting both innate and adaptive immune functions through AMP regulation. PMID: 21519404 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21519404&dopt=Abstract = URL to article

Cutaneous Rosai-Dorfman disease presenting as a granulomatous rosacea-like rashs. Chin Med J (Engl). 2011 Mar;124(5):793-4 Authors: Shi XY, Ma DL, Fang K PMID: 21518580 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21518580&dopt=Abstract = URL to article

[A giant rhinophyma.] Vestn Otorinolaringol. 2011;(2):68-69 Authors: Mustafaev DM, Svistushkin VM Rhinophyma is an infiltrative-productive stage of rosacea characterized by the formation of inflammatory nodes, infiltrates, and tumour-like outgrowths due to progressive hyperplasia of the connective tissue and sebaceous glands as well as persistent vasodilatation as a result of a chronic progredient disease. The authors describe a man with the severe form of rhinophyma in whom this condition was treated by the application of a cold plasma. A good cosmetic result with minimal scarring was achieved by this method. PMID: 21512493 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21512493&dopt=Abstract = URL to article

Lasers for vascular lesions: Standard guidelines of care. Indian J Dermatol Venereol Leprol. 2011 May-Jun;77(3):349-68 Authors: Srinivas CR, Kumaresan M Introduction: Lasers are a good therapeutic tool for congenital and acquired vascular lesions. Technological advances in lasers have reduced the adverse effects and increased the efficacy. Machines: Among the various lasers used for treating vascular lesions, pulsed dye laser (PDL) has the best efficacy and safety data. The other machines that are widely available are Nd:YAG laser and intense pulse light (IPL). Rationale and scope of guideline: Much variation exists in different machines and techniques, and therefore, establishing standard guidelines has limitations. The guidelines recommended here indicate minimum standards of care for lasers on vascular lesions based on current evidence. Physician Qualification: Laser may be administered by a dermatologist, who has received adequate background training in lasers during post-graduation or later at a center that provides education and training in lasers, or in focused workshops, which provide such trainings. He/she should have adequate knowledge of the lesions being treated, machines, parameters, cooling systems, and aftercare. Facility: The procedure may be performed in the physician's minor procedure room with adequate laser safety measures. Indications: PWS, hemangioma, facial telangiectasia, rosacea, spider angioma, pyogenic granuloma, venous lakes, leg veins. Contraindications: Absolute: Active local infection, photo-aggravated skin diseases, and medical conditions. Relative: Unstable vitiligo, psoriasis, keloid and keloidal tendencies, patient on isotretinoin, patient who is not cooperative or has unrealistic expectation. Patient Selection: Patient selection should be done after detailed counseling with respect to the course of lesions, different treatment options, possible results, cost, need for multiple treatments, and possible postoperative complications. Treatment Sessions: The number of treatments per lesion varies from 2 to 12 or more at 6-8 week intervals. All lesions may not clear completely even after multiple sessions in many cases. Hence, a realistic expectation and proper counseling is very important. Laser parameters: Laser parameters vary with area, type of lesion, skin color, depth of the lesion, and machine used. A test spot may be performed to determine individual specifications. Complications: Pain, edema, purpura, bleeding, scarring, postinflammatory hyperpigmentation/hypopigmentation, and atrophy changes. PMID: 21508585 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21508585&dopt=Abstract = URL to article

Diode laser treatment of rhinophyma. Clin Otolaryngol. 2010 Oct;35(5):442-4 Authors: Tahery J, Zakaria R, Natt RS PMID: 21108762 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21108762&dopt=Abstract = URL to article

Munich International Summer Academy of Practical Dermatology - ISA 2011. Acta Dermatovenerol Croat. 2011 Mar;19(1):71-72 Authors: The Munich International Summer Academy of Practical Dermatology - ISA 2011 will be held for the second time from July 24 till 29, 2011 in Munich, Germany. Founded in 2007 by the Department of Dermatology of the Ludwig-Maximilian University of Munich, the first meeting was a great success with more than 700 participating dermatologists form 38 countries around the world. From 2011 on, the Munich International Summer Academy of Practical Dermatology stands under the auspices of the German Dermatologic Society and will be held biannually with the aim to provide an intensive and compact one-week course of continuing medical education and practical training in dermatology. The clinically oriented program will encompass keynote and plenary lectures with updates from experts in various fields during morning sessions, and diverse hands-on courses, workshops, and meet-the-expert sessions in the afternoons. Thus, the program will attract both young colleagues in training for advancing and broadening their dermatological skills, as well as experienced dermatologists in practice and hospitals for refreshing and updating their expertise. This concept has been inherited by the German-speaking version of the congress, the Munich Educational Week for Practical Dermatology (Münchner Fortbildungswoche für Praktische Dermatologie), which can proudly look back to its more than 50-year history of success having emerged to Germany's second largest National Congress of Dermatology with more than 3500 participants in 2010. The Munich International Summer Academy will expand this educational platform to an international audience with English as the main official language. Scientific program The scientific program for the ISA 2011 is already secluded in large parts, and provides a blend of very enriching presentations. The organizers are very pleased to announce several internationally highly recognized keynote and plenary speakers who will review the latest developments from major areas of dermatology. Among them are: Richard Gallo, San Diego, USA (Inborn Immunity); John McGrath, London, Great Britain (Genetic Skin Diseases); Derek H. Jones, Los Angeles, USA (Aesthetic Dermatology); Dan Lipsker, Strasbourg, France (Autoinflammatory Disorders); Frank Nestle, London, Great Britain (Psoriasis); Jean-Paul Ortonne, Nice, France (Vitiligo); Eli Sprecher, Tel Aviv, Israel (Inherited Hair Diseases); and Gil Yosipovitch, Winston-Salem, USA (Chronic Itch). Further plenary lectures will cover important updates from a broad spectrum of different areas of dermatology, such as Acne and Rosacea, Atopic Eczema, Dermatosurgery, Environmental Dermatology, Hidradenitis Suppurativa, Infectious Skin Diseases, Inflammatory Skin Diseases, Laser therapy, Lichen Planus, Life-Threatening Dermatoses, Oncologic Dermatology, Pediatric Dermatology, Psoriasis, Scleroderma, Urticaria, and much more. Each day shortly after lunch, a one-hour symposium will provide new developments from dermatopharmacology and broaden the knowledge of important dermatological therapeutics with particular focus on alitretinoin, calcineurin inhibitors, and the field of aesthetic dermatology with fillers and botulinum toxin agents. Whereas the morning program is devoted to plenary lectures, the afternoon provides courses and parallel sessions offering the possibility to learn and discuss in depth special topics of daily practice with one or more specialists in smaller groups. For colleagues interested in dermatosurgery, there will be a suturing and knotting course on pig foot for beginners, and for the more advanced a virtual reconstruction course for flaps and grafts on mouse pads; for those interested in aesthetic dermatology, several courses will cover practical aspects of handling, performance, and potential risks of injections of different filler materials and botulinum toxins. In addition, there will be hands-on courses on dermatohistopathology, dermatoscopy, laser therapy, mycology, photodynamic therapy, phototherapy, sonography, and trichology. Workshops and meet-the-expert sessions covering acne, anti-aging therapies, contact dermatitis, lupus erythematosus, phytotherapy, rosacea, scleroderma, sexually transmitted diseases, and tropical dermatology will complement the comprehensive program from which participants can choose the topic in which they are most interested. Special offer for low-income countries The Organizing Committee of the ISA 2011 is proud to offer 100 travel grants to young colleagues in training from low-income countries to support their participation at the ISA 2011 congress. Munich - a city worthwhile to visit The ISA 2011 will be held in mid-summer during the loveliest season in Germany expected to offer warm and sunny low-humidity weather. The venue is located in close walking distance to the inner center of Munich and allows the combination of congress participation with a bright tourist value. Munich as a cosmopolitan city and capital of Bavaria features a rich cultural life including important collections of classic, modern and contemporary art, in July the famous Munich Opera Festival, shopping at the prestigious Maximilian Street, and an overwhelming number of delicious restaurants. After the intensive educational program, a cold Bavarian beer in one of the many traditional beer gardens will help refreshing oneself for the next congress day. Social Program Aside from the intense educational program, the ISA 2011 will give participants an opportunity to meet colleagues from all over the world, to make new personal contacts, and to enjoy international friendship. The social program will offer two highlights, a Bavarian Evening in a traditional Bavarian Beer Hall, and a boat tour to the stunning Starnberger See with a gorgeous impression of the beautiful Bavarian countryside nearby the Alps. Both had become an unforgettable experience of Bavarian life and tradition for the participants of the first ISA congress. Detailed information and registration www.isa2011.com; isa@interplan.de or Department of Dermatology and Allergology, Ludwig-Maximilian University Munich, c/o Claudia Rolle, Frauenlobstr. 9, D-80377 Munich, Germany; phone +49-89-5160-6005; E-mail: Claudia.rolle@med.uni-muenchen.de. PMID: 21489370 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21489370&dopt=Abstract = URL to article

Discoloration of nail beds and skin from minocycline. CMAJ. 2011 Feb 8;183(2):224 Authors: Tavares J, Leung WW PMID: 21098068 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21098068&dopt=Abstract = URL to article

Worsening of rosacea in patients treated with dihydropyridine calcium channel blockers: a clinical observation. Hypertens Res. 2011 Mar 31; Authors: Natale F, Cirillo C, Granato C, Concilio C, Siciliano A, Credendino M, Aronne L, Calabrò P, Russo MG, Calabrò R PMID: 21451527 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21451527&dopt=Abstract = URL to article

Transmission of Rosacea from the Graft in Facial Allotransplantation. Am J Transplant. 2011 Mar 28; Authors: Kanitakis J PMID: 21443678 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21443678&dopt=Abstract = URL to article

Cystic lesions associated with rhinophyma treated with an ablative fractional yttrium-scandium-gallium-garnet laser. J Cosmet Laser Ther. 2010 Dec;12(6):261-3 Authors: González JA, Boixeda P, Díez MT, Markixana IA, Jaén P PMID: 21142734 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21142734&dopt=Abstract = URL to article

Nailfold capillaroscopy as a diagnostic and prognostic method in rosacea. An Bras Dermatol. 2011 Feb;86(1):87-90 Authors: Fonseca GP, Brenner FM, Muller CD, Wojcik AL BACKGROUND: There is no appropriate and reliable method of evaluating and monitoring severity in rosacea. OBJECTIVE: To determine the importance of nailfold capillaroscopy as a diagnostic and prognostic method for patients with rosacea. METHODS: A cross-sectional study where eight patients with rosacea and 8 control subjects were submitted to nailfold capillaroscopy from May to July 2009. We collected clinical data related to gender, age, skin phototype, and rosacea stage according to Plewig and Kligman classification and the classification of the National Rosacea Society. Additionally, we evaluated the progression of the disease and treatment therapies previously used. RESULTS: The majority of the patients evaluated (6 out of 8 patients) had rosacea subtype I (vascular) or erythematotelangiectatic rosacea. The mean duration of the disorder was 5.96 years, and 87.5% of the patients were under treatment with topical metronidazole. Nailfold cappilaroscopy showed that evidence of devascularization was absent in both groups. CONCLUSION: Nailfold capillaroscopy presents a nonspecific pattern and does not seem to help in the diagnosis or prognosis of rosacea. PMID: 21437527 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21437527&dopt=Abstract = URL to article

Interventions for rosacea. Cochrane Database Syst Rev. 2011;3:CD003262 Authors: van Zuuren EJ, Kramer S, Carter B, Graber MA, Fedorowicz Z Rosacea is a common chronic skin condition affecting the face, characterised by flushing, redness, pimples, pustules, and dilated blood vessels. The eyes are often involved and thickening of the skin with enlargement (phymas), especially of the nose, can occur in some patients. A range of treatment options are available but it is unclear which are the most effective. PMID: 21412882 [PubMed - in process] http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=21412882&dopt=Abstract = URL to article