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    • "Praxis Biotechnology is developing a medication to reduce inflammation associated with rosacea without affecting the rest of the body." Albany biotech startup wins $50K at business competition, By Madison Iszler, Albany Times Union
    • I found this article in the Houston Chronicle interesting since I take a 81 mg enteric coated Aspirin every day:  "Q: This is a true story. In the 1950s, my grandmother was taking a "heart pill" her doctor had prescribed. The older doctor retired, and Granny went to see the new doctor to get her heart pill refilled. The young doctor told her: "Mrs. G., this is nothing but aspirin. There is nothing wrong with your heart." He refused to refill her heart pill. Three weeks later she died of a heart attack. That was in the 1950s, before any research had been done on the effects of aspirin and the heart. A: It took decades for the medical profession to recognize how useful aspirin could be in preventing heart attacks. A recent Swedish study discovered that people who discontinued low-dose aspirin were 37 percent more likely to have a hospitalization, heart attack or stroke (Circulation, online, Sept. 26, 2017). The investigators suggest that there may be rebound blood clotting when aspirin is stopped suddenly. Other research also has shown a link between aspirin discontinuation and serious cardiovascular events. If people need to stop aspirin prior to surgery or because of side effects, they should do so under careful medical supervision." Sudden discontinuation of aspirin could create serious issues
      By Joe Graedon and Teresa Graedon, Houston Chronicle
    • A PRACTICAL UNDERSTANDING OF ROSACEA
      PART 1:
      HEAT REGULATION AND THE
      WARM ROOM FLUSH PHENOMENON
      By Colin Dahl
      Chief Scientist, Australian Sciences
    • dazed1 has been posting a lot in RF and recently posted about a natural topical treatment using oils from plants that you can make yourself. Her post at RF explains the process in details. This isn't for the lazy and requires a lot of work. If any of you try this treatment yourself, please post here in this thread the results. 
    • Hi, thanks for including my post.   If you go back to the standard animal diet, you might notice that you wont have issues as well, systematic inflammation caused by animal protein and high glycemic index/insulin foods is not something that is happening very soon. So the rest period of 2 weeks, might give you few days extra before the problem start arise, sure it can happen at once but most of the time is slow process. I can go on and on, but i'm short on time so i will leave out some videos with the subject i'm talking about, and that is the harmful effects of animal protein.                
    • "Spend more than three minutes talking to any dermatologist ever, and they’ll inevitably start raving about three things: 1. Wearing sunscreen every single day until the moment you die, 2. How Accutane is an actual miracle drug, and 3. Why everyone should be slathering vitamin C on their face every single morning, like it’s the antidote to sadness. (And if your skin is an issue, then yeah—it kind of is the cure)." Why Every Single Derm Thinks You Should Be Using Vitamin C on Your Face, by CHLOE METZGER, marie claire

    • "The Vivace is effective for reducing wrinkles and rosacea/spider veins, eliminating acne scars and stretchmarks and skin tightening. While most see immediate results, Dr. Shah recommends that her patients undergo three treatments for optimal results."  Expert NYC Dermatologist Introduces Breakthrough RF Microneedling Treatment in Manhattan
      PRESS RELEASE PR Newswire, Markets Insider "We start with the most revolutionary, best-in-class Vivace Microneedling RF device, designed for an incomparable, comfortable patient experience. Only The Vivace boasts a robotic motor that brings discomfort to a virtual zero compared to any other device you will find in your physician’s office. We recommend a personally compounded numbing cream, the best available today, and our carefully developed recovery system to make sure no one knows you just had a treatment today. The results are immediate and also improve over time, giving you the best of both worlds." Vivace Experience
    • Facial erythema is a condition where the face turns red and this type of condition is prominently seen in fair individuals. This facial redness arises due to the dilation of the cutaneous blood vessels and increased blood flow up to the skin. Facial erythema many times goes undiagnosed among the dark-skinned individuals. There are many factors responsible for the facial erythema, including the primary skin diseases like rosacea and systemic illness, and perioral dermatitis. Facial erythema condition is characterized by itching, redness, burning skin, dry skin, visible blood vessels, flushing, and pain. This disease affects many people worldwide and is a very common facial skin disease, is chronic and predominantly found in females with fair skin. Facial Erythema Treatment Market to Develop Rapidly by 2027, Find Market Research  Request Sample Report 
    • "We may love the way a bit of blush can enliven the skin, but rosacea, blotchiness and general redness on the face is different. We want to be the ones to decide where a red flush belongs, thank you very much. So what can we do about unwanted redness?" 12 Ways to Keep Calm and Get Rid of Skin Redness, by HEATHER CICHOWSKI, The Fashion Spot some of the products in the above article can be found in our store which the RRDi receives a small affiliate fee. Thanks for shopping through us!
       

    • image courtesy of Mark's Daily Apple In the spirit of 'everything rosacea' I have included a report by Darcelle (post no 23) at RF that "eliminating animal products from your diet [will] help with the rosacea," hence, an animal diet triggers rosacea. This is ironic because Darcelle started the thread with the title, Rosacea AFTER Going Vegan, but she changes her view as you read through the thread.  Darcelle cites two references in post no 23, the first, Lindsay S Nixon, who interviews Mary Lou who reports that eating a plant based diet cleared her rosacea in just 30 days, and the other example about Silpa Reddy who reports her "rosacea has lessened with every month."   dazed1 and MissM both advocate a plant based diet in this thread (posts 71 thru 75). dazed1's post no 39 explains in more detail how to implement a plant based diet supplemented with certain nutrients and a list of foods prohibited (be sure to pay extra attention to the little smiley that is shaking its head NO "diet - absolutely" which indicates the foods on the list are prohibited. You should be aware that rosacea triggers are basically anything put on a list made up of anecdotal reports from rosacea sufferers who say 'this triggers rosacea."  There are no clinical papers with double blind, placebo controlled studies done that substantiates any trigger. Furthermore, there is no known proposed rosacea trigger that will produce a rosacea flareup in every rosacea sufferer. All rosacea triggers are simply proposed. A proposed trigger may or may not trigger your rosacea. All you can do is just see if a proposed trigger on the list triggers your rosacea.  More on trigger avoidance.  It is only fair to include this for those who may want to try a plant based diet and see if it clears rosacea. If you have something to report about this please reply to this post. So the proponents of this particular plant based diet (with certain foods prohibited for two weeks) say you should start improving in two weeks to a month. After your improvement the real test is to go back on the animal diet you previously had before to see if your rosacea returns. That should be enough evidence to convince someone that an animal diet triggers rosacea. Then to prove it works go back on the particular plant based diet that is mentioned in this post to see if your rosacea is improved again or controlled to prove beyond any doubt this type of diet works. If there are any takers for this diet please post your results here.   
    • "In a recent interview, Zoe D. Draelos, MD, Consulting Professor of Dermatology at Duke University School of Medicine, High Point, NC, and one of the senior investigators of ivermectin 1% cream, discussed how it works, and what it is expected to contribute in the management of patients with rosacea." Payer Perspectives in Dermatology - Rosacea
      Caroline Helwick, American Health & Drug Benefits
    • "Roanhorse, who works professionally as a federal programs director for the Education Department of the Jicarilla Apache Nation, designed the skin care line, Skindigenous, with natural ingredients, geared specifically toward Natives with sensitive skin. She also aims to help people learn about the dietary and environmental factors that can lead to skin conditions like rosacea and acne." Native communities look to DIY model to get online
      By Sami Edge | The New Mexican
    • "If you’re constantly battling acne, eczema, rosacea or any number of other skin disorders, the solution may be in your fridge — not your bathroom cabinet. According to many progressive dermatologists, probiotic-rich foods like yogurt, kefir and kombucha can be even more effective in treating stubborn skin conditions than store-bought or prescription skin creams." Should You Put Probiotics On Your Face?, by Liivi Hess, Alternative Daily Probiotics in the RRDi Store
    • Rosacea and alcohol intake. J Am Acad Dermatol. 2017 Nov 07;: Authors: Drago F, Ciccarese G, Herzum A, Rebora A, Parodi A PMID: 29126626 [PubMed - as supplied by publisher] {url} = URL to article
    • "This study indicates that retinaldehyde has beneficial effects on the vascular component of rosacea." Dermatology 1999;199(suppl 1):53–56 
      (DOI:10.1159/000051380)
      Retinaldehyde Alleviates Rosacea
      Vienne M.-P. · Ochando N. · Borrel M.-T. · Gall Y. · Lauze C. · Dupuy P. "Retinal is also known as retinaldehyde. It was originally called retinene, and renamed after it was discovered to be vitamin A aldehyde." Wikipedia
    • "“As an intermediary step between topical antibiotics and oral isotretinoin, we propose that topical tretinoin may be effective in the management and reduction of rosacea symptoms,” Emily Forward, MD, of the University of Sydney, said at the meeting. There has been recent discussion regarding the use of low-dose isotretinoin in the treatment of rosacea, but safety with long-term use is an issue, she noted." Topical tretinoin resolves inflammatory symptoms in rosacea, in small study
      Publish date: May 17, 2017
      By: Bianca Nogrady, Dermatology News
    • Related Articles Rhinophyma graft for repair of the phymatous nasal ala. J Am Acad Dermatol. 2017 04;76(4):e123 Authors: Malone CH, DeCrescenzo AJ, Subrt AP, Wagner RF PMID: 28325413 [PubMed - indexed for MEDLINE] {url} = URL to article
    • Related Articles Rhinophyma graft for repair of the phymatous nasal ala. J Am Acad Dermatol. 2017 04;76(4):e123 Authors: Malone CH, DeCrescenzo AJ, Subrt AP, Wagner RF PMID: 28325413 [PubMed - indexed for MEDLINE] {url} = URL to article
    • "Dr. Edina Garaczi emphasizes that all rosaceous patients should be treated personally. It is not enough to focus only on skin symptoms, there is not a panacea that is equally well-liked for everyone, everyone has to individually find and deal with rosacea provocative factors." Dr. Garaczi Edina's dermatologist-allergist also draws attention to things that many of us can know about rosaceous skin, Vital Article in Hungarian. Use Google Translate. 
    • "Sugar and trans fats also cause inflammation, which can lead to acne and other skin problems. Inflammation is also the main cause of many chronic diseases....Foods such as bagels, oatmeal, pretzels, pasta, and cereal have been proven to accelerate the skin's aging process and cause acne, wrinkles and rosacea by converting refined carbs into sugar and then glucose, which damages collagen." Avoid These Foods If You Want To Keep Your Youthful Glow
      The damage of a poor diet is aging you from the inside out before you even start to feel the effects.
      Rose Reisman Health and Wellness Expert, Caterer, Restaurateur, and Author, HuffPost
    • "While the original classification system designated the most common groupings of primary and secondary features as subtypes, the committee noted that because rosacea appears to encompass a consistent inflammatory continuum, it now seems appropriate to focus on the individual characteristics, called phenotypes, that may result from this disease process. Observing the respective phenotypes in clinical practice will also encourage consideration of the full range of potential signs and symptoms that may occur in any individual patient, and assessment of severity and the selection of treatment may be more precisely tailored to each individual." NRS Introduces New Standard Classification and Pathophysiology of Rosacea
      By Brad Bennett , in PR PR Health on November 8, 2017, The Daily Telescope
    • "Retinoids (the umbrella term for all forms of the vitamin A derivative, including the popular OTC version retinol) are the Screech of the skin world: irritating. So women who have had reactions to other skin products—or who have tried a retinoid in the past and ended up tingly and flaky—think it's not for them.... ....Rosacea itself is considered inflammatory and treated with products labeled "anti-redness"—so why willfully add more flame to the fire? The facts: It's not a good idea to use a retinoid in the midst of an outbreak, we'll give you that. Otherwise, however, you shouldn't have any additional redness after the first two weeks of use. And, in fact, one study found that retinoids might even be a treatment for rosacea." 5 Myths About Retinoids You Should Stop Believing ASAP, BY KAYLEIGH DONAHUE HODES November 8, 2017, Women's Health
    • "Whether you have acne, rosacea, or allergy-prone skin, you may think there's not much you can use on your touchy complexion. But the truth is, you could be seriously limiting your skin care by swearing off certain products. Here's the truth behind some of the most common sensitive skin myths...." 3 Sensitive Skin Myths—Busted!, Women's Health
    • " “True sensitive skin is a genetic predisposition and can be thought of as a built-in case,” she says. It’s found in individuals with very fair skin, usually of Northern European ancestry. This kind of skin is more delicate in make-up, with lower amounts of pigment and blood vessels that are closer to the surface of the skin, making it prone to redness, she explains. Sensitive skin has a less effective protective outer layer on the skin’s surface—which is known as the epidermis—so irritants like allergens and microbes can more easily penetrate skin and reach more deeply, causing reactionary inflammation. Skin itches, scales, blisters, flushes, and breaks out under conditions that wouldn’t bother regular skin types........ ......Meanwhile, sensitized skin occurs due to environmental effects and is “a growing phenomenon,” says Hammerman. It happens due to a number of factors, including over-exfoliation, cosmetic treatments like chemical peels and laser devices, exposure to stress, chemicals, smoking, alcohol, and pollution. Fortunately, sensitized skin is a lot easier to calm than clinically sensitive skin." [bold added] If You Think You Have Sensitive Skin, You Probably Don't - Here’s how to tell if you really have it. BY GRACE GOLD, Women's Health, December 16, 2015
    • "The National Rosacea Society (NRS) announced today (11/8/17) that a new standard classification and pathophysiology of rosacea has been published in the Journal of the American Academy of Dermatology....While the original classification system designated the most common groupings of primary and secondary features as subtypes, the committee noted that because rosacea appears to encompass a consistent inflammatory continuum, it now seems appropriate to focus on the individual characteristics, called phenotypes, that may result from this disease process. Observing the respective phenotypes in clinical practice will also encourage consideration of the full range of potential signs and symptoms that may occur in any individual patient, and assessment of severity and the selection of treatment may be more precisely tailored to each individual....According to the new system, the presence of one of two phenotypes – persistent redness of the facial skin or, less commonly, phymatous changes where the facial skin thickens – is considered diagnostic of rosacea....The committee noted that, as with the original classification of rosacea, the updated standard system is considered provisional and may require modification as the causes and pathogenesis of rosacea become clearer, and its relevance and applicability are tested by investigators and clinicians." NRS Introduces New Standard Classification and Pathophysiology of Rosacea, Cision, PRWeb
    • "As celebrity aesthetician Angela Caglia tells us, alcohol dehydrates your skin and robs it of its vital nutrients, so excessive alcohol consumption (think: drinking like you're still in college), can contribute to skin's premature aging in the long term, and bloating, puffiness, enlarged pores, dullness, and rosacea the day after....Caglia recommends living (or drinking) by the general rule of thumb that the clearer the alcohol, the better it'll be for your skin. Red wine, dark whiskey, a piña colada — these are the things a killer hangover and a puffy face are made of. Straight-up, no frills shots? Surprisingly not so bad." Here's how different types of alcohol affect your skin — and the only one you should order,  
      Megan Decker, Refinery29, Insider Health
    • Related Articles Topical a-Agonist Therapy for Persistent Facial Erythema of Rosacea and the Addition of Oxmetazoline to the Treatment Armamentarium: Where Are We Now? J Clin Aesthet Dermatol. 2017 Jul;10(7):28-32 Authors: Del Rosso JQ Abstract
      The presence of vasoactivity in rosacea-affected skin led to the development of two topical α-adrenergic receptor agonists, brimonidine tartrate 0.5% gel and oxymetazoline hydrochloride 1% cream, both approved by the United States Food and Drug Administration for treatment of persistent facial erythema of rosacea. In this article, the author discusses challenges related to the treatment of persistent facial erythema of rosacea and the use of a-agonist therapy. The author also discusses cases of worsening of facial erythema after the application of brimonidine, as well as briefly reviews recently reported clinical data on oxymetazoline. Finally, the author attempts to differentiate some potential mechanistic differences between these two agents.
      PMID: 29104721 [PubMed] {url} = URL to article
    • Comorbidities in rosacea: A systematic review and update. J Am Acad Dermatol. 2017 Oct 26;: Authors: Haber R, El Gemayel M Abstract
      BACKGROUND: Rosacea is linked to abnormalities of cutaneous vasculature and dysregulation of the inflammatory response. Recent reports on rosacea have shown a significant association with cardiovascular, gastrointestinal, and psychiatric diseases, all of which may affect morbidity and mortality among these patients.
      OBJECTIVE: To review available data regarding comorbidities associated with rosacea, discuss their pathogenesis, and highlight the evaluation of affected patients.
      METHODS: We performed a complete and systematic literature review in PubMed/Medline, Embase, and the Cochrane Collaboration databases, searching for all articles on possible associated diseases that have been reported with rosacea, with no limits on publication date, participant age, sex, or nationality.
      RESULTS: A total of 29 studies were included in this systematic review, including 14 case-control, 8 cross-sectional, and 7 cohort studies. Statistically significant association with rosacea has been mostly demonstrated with depression (n = 117,848 patients), hypertension (n = 18,176), cardiovascular diseases (n = 9739), anxiety disorder (n = 9079), dyslipidemia (n = 7004), diabetes mellitus (n = 6306), migraine (n = 6136), rheumatoid arthritis (n = 4192), Helicobacter pylori infection (n = 1722), ulcerative colitis (n = 1424), and dementia (n = 1194).
      LIMITATIONS: Limitations included the accuracy of the published data, potential patient selection, and possible confounding factors. The true nature of the drawn correlations is uncertain, and causality cannot be established.
      CONCLUSIONS: Rosacea is associated with a number of systemic disorders. Recognition of these conditions is critical to providing appropriate screening and management of affected patients.
      PMID: 29107339 [PubMed - as supplied by publisher] {url} = URL to article
    • Rosacea comorbidities and future research: The 2017 update by the National Rosacea Society Expert Committee. J Am Acad Dermatol. 2017 Nov 01;: Authors: Gallo RL, Granstein RD, Kang S, Mannis M, Steinhoff M, Tan J, Thiboutot D PMID: 29102687 [PubMed - as supplied by publisher] {url} = URL to article
    • Role of Topical Oxymetazoline for Management of Erythematotelangiectatic Rosacea. Ann Pharmacother. 2017 Nov 01;:1060028017740139 Authors: Hoover RM, Erramouspe J Abstract
      OBJECTIVE: To review and summarize topical oxymetazoline's pharmacology, pharmacokinetics, efficacy, safety, cost, and place in therapy for persistent redness associated with erythematotelangiectatic rosacea.
      DATA SOURCES: Literature searches of MEDLINE (1975 to September 2017), International Pharmaceutical Abstracts (1975 to September 2017), and Cochrane Database (publications through September 2017) using the terms rosacea, persistent redness, α -agonist, and oxymetazoline.
      STUDY SELECTION AND DATA EXTRACTION: Results were limited to studies of human subjects, English-language publications, and topical use of oxymetazoline. Relevant materials from government sources, industry, and reviews were also included.
      DATA SYNTHESIS: Data support the efficacy of oxymetazoline for persistent facial redness. Little study beyond clinical trials cited in the drug approval process has been conducted. Current data suggest that oxymetazoline is similar in safety and efficacy to brimonidine. Head-to-head comparisons of topical α-agonists for erythema caused by rosacea are needed.
      CONCLUSION: The topical α-agonist, oxymetazoline, is safe and effective for reducing persistent facial redness associated with erythematotelangiectatic subtype of rosacea. Health care practitioners selecting among treatments should consider not only the subtype of rosacea but also individual patient response, preference, and cost.
      PMID: 29094614 [PubMed - as supplied by publisher] {url} = URL to article
    • "If you live with a common skin condition like eczema, psoriasis, or rosacea, you've probably tried every treatment in the book—but there's a reason why many sufferers swear by aloe vera. "With powerful phytochemicals that help reduce inflammation, aloe vera has been found to be an effective anti-inflammatory agent," says Brandon. So the next time you experience a flare-up, add some aloe vera to your normal topical treatment and try these 16 foods that ease painful inflammation." 10 Healing Benefits of Aloe Vera for Breakouts, Burns, and More
      If you think aloe vera is just for bug bites and sunburns, think again.
      BY ZARAH A. KAVARANA, Reader's Digest
    • The NRS has now moved forward with classifying rosacea into phenotypes with this published paper:  Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee .
    • "The national survey on rosacea was conducted with over 500 patients suffering from rosacea and about 300 dermatologist, the main finding included the patients struggle emotionally and low self-esteem, don’t feel comfortable talking to their physician, and impact their social and psychological life. Economic productivity loss due to skin diseases is increasing at an alarming rate. According to American Academy of Dermatologists (AAD), skin diseases affect not just productivity but confidence levels of patients, creating passive impact on long term work stature." Research Details Developments in the Rosacea Treatment Market
      BY POOJA, MilTech
    • "While alcohol may have contributed to some of that headache, excess sugar is likely the real culprit and may be currently wreaking havoc on skin....After a night of bad habits, “the gut develops an imbalance of bad bacteria, and the body can wake up craving even more sugar.” Snyder suggests taking a probiotic supplement to rebalance blood sugars, “give you energy, and reduce mood swings.”....Skin, too, can see the effects of a heavy night of trick-or-treating. “Excess sugar can cause inflammation and even rosacea,” explains top New York City facialist Mzia Shiman who is responsible for the flawless glow of the Victoria’s Secret Angels. First, the pro recommends drinking “a ton of water” to start the de-puffing process, and, if possible, have an at-home LED light mask at the ready. “The red lights can help calm skin and soothe redness,” she says." Do You Have a Halloween Candy Hangover? Read This
      by JENNA RENNERT, Vogue More on Sugar and Rosacea
    • "A dermatologist in Washington, D.C., was surprised to discover that one of her patients was using a powerful steroid cream bought without a prescription to treat a rash." Imported Skin Creams Can Pose Unexpected Risks
      90.3 KAZU
      CSU Monterey Bay
      A Community Service of California State University Monterey Bay More on Steroid Induced Rosacea
    • "...I'm intensely critical of what I'll put on my own skin. (Rosacea plus derm horror stories will do that to you.)....As a disclaimer on the instructions warns pale people, the lifting compounds that stimulate blood flow to your face may leave you red, which is a slight understatement. Immediately after my face is angry. But trust the process.....There was still some residual redness, but if I can find something that solves that problem, rest assured you'll know about it." I Tried the Hanacure Face Mask: Instagram’s Famous 'Grandma' Treatment
      BY LINDSAY SCHALLON, Glamour
    • Related Articles Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee. J Am Acad Dermatol. 2017 Oct 28;: Authors: Gallo RL, Granstein RD, Kang S, Mannis M, Steinhoff M, Tan J, Thiboutot D Abstract
      In 2002, the National Rosacea Society assembled an expert committee to develop the first standard classification of rosacea. This original classification was intended to be updated as scientific knowledge and clinical experience increased. Over the last 15 years, significant new insights into rosacea's pathogenesis and pathophysiology have emerged, and the disorder is now widely addressed in clinical practice. Growing knowledge of rosacea's pathophysiology has established that a consistent multivariate disease process underlies the various clinical manifestations of this disorder, and the clinical significance of each of these elements is increasing as more is understood. This review proposes an updated standard classification of rosacea that is based on phenotypes linked to our increased understanding of disease pathophysiology. This updated classification is intended to provide clearer parameters to conduct investigations, guide diagnosis, and improve treatment.
      PMID: 29089180 [PubMed - as supplied by publisher] {url} = URL to article
    • Related Articles Evidence-based update on rosacea comorbidities and their common physiologic pathways. J Am Acad Dermatol. 2017 Oct 28;: Authors: Holmes AD, Spoendlin J, Chien AL, Baldwin H, Chang ALS Abstract
      Rosacea is a common chronic inflammatory disease affecting the facial skin whose etiology and pathophysiology are the subject of much investigation. Risk factors include genetic and environmental elements that may predispose individuals to localized inflammation and abnormal neurovascular responses to stimuli. Recent studies have introduced an array of systemic rosacea comorbidities, such as inflammatory bowel disease and neurologic conditions, that can be challenging to synthesize. We critically review the current data behind reported rosacea comorbidities and identify and highlight underrecognized physiologic mediators shared among rosacea and associated comorbidities. This information may be helpful in addressing patient questions about potential systemic implications of rosacea and can serve as a candidate platform for future research to understand rosacea and improve treatments.
      PMID: 29089181 [PubMed - as supplied by publisher] {url} = URL to article
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