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About jbamford

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    MAC Member

RRDi required

  • Are you a rosacean?
  1. One recent example in which genes probably have a role, apologies for responding to myself! Yamasaki K et al Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat Med 2007 Aug: 13:975 suggests that overexpression of of one enzyme (kallikrein 5) which breaks apart cathelicidin may produce rosacea signs and symptoms.
  2. Agree this is likely to be genetic condition with many known environmental/dietary triggers(I favor something related to lipase, regardless of my unconfirmed idea). I do not think it will be recessive gene or genes with 40% of rosaceans having family members involved, dominant with variable penetrance more likely. But, genetic is likely to be worth RRDi effort. I do not have a favored (I do not work in genetics) researcher to suggest. Supporting this (your interest and funding scientists already working on this) seem one good starting place.
  3. RTC's, IRBs and Cochrane Reviews: RCT - randomized controlled studies (I'm not a good typist) considered the best evidence IRB - institutional review board - entity doing human research ethical review, consenting, methodology approval before study begins Cochrane Reviews (google it) The producer of evidence for evidence based practice Dr. Zuren has done reviews, I believe Thanks for clearing up my understanding on RRDi innitiatives. Studies of rosaceans, like those done by NRS, can add important information. Rosaceans suggesting their questions f
  4. Sherry, First, I think low glycemic and dairy free have proponents (articles for decreased androgen and acne with low glycemic diet- R Smith et al Asia Pac J Clin Neutr 2005:14(Suppl):S97). Two years ago low glycemic was being considered as to how to get NIH behind such a project which, I think, would be very expensive and be considered after a RTC on diet/common acne. Second, in the postings above, I was surprised to read (Brady pos) that RRDi would not support a project not approved by (us) the MAC. I had thought we were to offer our help/knowledge or even effort but unlike other boar
  5. Web Very Complete, Just Takes New Learning. Having the send button at top of email window, instead of scrolling down to find it. Not sure what you can do for elders (SS recepient myself) to make threads/replies easier to visualize. I used to like Compuserves visible techniques.
  6. Just trying to get in that 15 minutes/month takes time. I'm only now trying to work through some of your basic information. Most helpful to me, so far: Telling computer to remember me, signing me in on each of computers (work, home where I have time) Just as I try to send this to you, Brady, the screen does not say POST or Send. I'll try "+", that ain't it. I have to scroll down to look for it...beyond options, attachments, post icons. Possibly it should be on top as with email sending.
  7. I am a member of a large multispecialty group (Derm Section is 5 MD's and 1RNC). Although I began with Internal Medicine and had office general practice experience, I've just done Dermatology for 33 years (It continues to inspire me with mysteries and individual who come to my office). Because residency training required a research project, when I had been in practice a few years, then I gave a clinical project a try. I've enjoyed trying to learn and add new medical information. For the last 10 years I've focused on rosacea. I've been fortunate enough to assoicated with epidemiologists
  8. Anti-inflammatory 'antibiotics' which improve rosacea are the same used as part of complex but short regimens (7-14 days) to cure H pylori form the GI tract. When you look at patients 3 months after the cure of H pylori, the Hp is no longer present yet the rosacea is unchanged. http://www.ncbi.nlm.nih.gov/entrez/query.f...t_uids=10376693 It is expected that while on those medications rosacea would improve rosacea while taken and for some time after completing them. If that improvement was due to their effect on Hp it should be a permanent benefit. The low glycemic diet effect on acne an
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