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The RRDi is an Amazon Affiliate. By clicking below on the image and purchasing the item, the RRDi receives a small fee. Thanks. Please post your experience using this product in this thread.

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The RRDi is an Amazon Affiliate. By clicking below on the image and purchasing the item, the RRDi receives a small fee. Thanks. Please post your experience using this product in this thread.

This may help you save money with the Soolantra Savings Program which is mentioned in the news thread about Soolantra.

Image of Demodex Folliculorum courtesy of National Geographic - by Darlyne A. Murawski Demodex mites are usually on all adults and what they may have a symbiotic relationship. Demodex do not appear on babies but show up later in life. Demodex feed on sebum and hang around hair follicles. They like warmth so they usually are on the face. They do not like light so they bury themselves deep into the skin during the day and come out at night and move around. They have no way to eliminate their waste and eventually die. This poses no problem for most humans who haven't a clue these demodex are on their face. The history of demodex is that there are only two kinds that appear on humans even though there are dozens of kinds and their connection to acne rosacea goes way back and has been debated by the medical authorities for over a hundred years. In rosacea patients the number of demodex are greater than in the average population who do not suffer from rosacea. Demodex density counts are one way to quantify. Recent studies confirm that a bacteria in the mites (Bacillus oleronius, Staphylococcus epidermidis, Bartonella quintana, Bacillus pumilus or Bacillus cereus) may have the clue to why rosacea appears. Whether the mites cause the rosacea or the rosacea increases the mite density count is a chicken or egg question. Most studies conclude that a higher demodex density count appears on humans who have rosacea. Treatment for demodectic rosacea, a variant of rosacea, is one way to confirm the diagnosis of demodectic rosacea. However, you should be aware if you treat for demodex it gets worse before it gets better. Not all cases of rosacea are demodectic. Dermatologists have been treating recently with Soolantra. Other treatments include the ZZ cream, horse paste and other over the counter treatments. We now have all the demodex posts in one category. A growing list of different types of bacteria is associated with these mites and rosacea. Demodectic Rosacea is a variant of rosacea. What is the difference between demodex and bed bugs?

As of this date, there are no reports in medical literature researching contraceptives and rosacea, however, there are plenty of discussions, articles and posts on this subject. We will use this FAQ as a source to keep this discussion in this thread. If you have anything to add please post in this thread. One of the rosacea triggers is menopause, so logically the hormones are somehow involved, but we have no clear understanding of how. [1] Some physicians prescribe antihistamines, antidepressants, low-estrogen birth control pills [2], diuretics, or an anti-dandruff shampoo containing zinc for the flushing that results from menopause. [3] Some anecdotal reports indicate that taking birth control pills improves rosacea. [4] Another anecdotal report indicates that going off birth control for one day improved rosacea. [5] Conversely, there are reports of women who go on birth control that increase rosacea flareups. [6] From an article posted at the dermatologist “We’re not certain of the clinical significance of the skin production of androgens because a lot is being made by the ovaries or testes. But, the skin is a large organ, so even if it’s involved in any respect in androgen metabolism, it could play a role in acne,” says Diane M. Thiboutot M.D., a Professor of Dermatology at the Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center. “It might be that women with acne may have greater local production of androgen in their skin that could in part account for the presence of acne. Many of our female patients with acne were found to have high levels of testosterone. Agents that block adrenal production of androgens are oral contraceptives and low-dose glucocorticoids. “Most times we use prednisone at a low dose because there seems to be increased risk of adrenal suppression with dexamethasone,” says Dr. Thiboutot. “While we have patients on treatment with dexamethasone or prednisone for congenital adrenal hyperplasia, it’s important to know whether your therapy is actually reducing those androgens, so you may want to check the serum dehydroepiandrosterone sulfate (DHEAS) to see if you’re bringing that down into the normal range.” Even on low-dose prednisone, adrenal suppression could still occur, so you may want to refer to an endocrinologist or an internist to have cortisol checked or to check adrenal function in general." Oral contraceptives contain a low-dose of an estrogen and a progestin. Studies show that most oral contraceptives used to treat acne have similar effectiveness, around a 45% reduction in inflammatory lesions. However, a novel progestin has been introduced called drospirenone, which is a derivative of 17-spironolactone, and it is found in the Yasmin brand oral contraceptive, which contains about 30 µg of estrogen. According to Dr. Thiboutot, a small trial for this contraceptive involving 128 women showed about a 60% lesion reduction over 9 months. Phase III trials for this therapy are in progress. Many patients are concerned about the interaction between oral contraceptives and antibiotics. “The gut flora is needed to cleave estrogen from the conjugated estrogen in the oral contraceptives, and the risk of an interaction is greatest with tetracyclines,” says Dr. Thiboutot. “But the number of reports in the literature is actually small. However, I think that we should discuss this with our patients.” [7] End Notes [1] birth control Q&A: Birth Control & Topical Medication, NRS [2] "The oral contraceptives chlormadinon acetate/mestranol (Ovosiston) and the antiandrogen agent cyproterone have been suggested as being effective hormonal treatments for rosacea." P T. 2009 Jan; 34(1): 38–45. Rosacea: A Review Brittney Culp, BA and Noah Scheinfeld, MD [3] Women May Need Added Therapy Lynn Drake, MD, Editor, NRS Rosacea Revew [4] sunshine12, Rashadooks, cas, [5] lexiophile [6] amethystice215 [7] What's New for Treating Acne By Michael S. Krivda, the dermatologist

Winston-Salem Journal

Exactly How to Get a Flawless Wedding Complexion, No Matter Your Skin Issues, by Kate Somerville, Popsugar

One of the theories of the cause of rosacea is an overactive immune system. "In a new study published in the Journal of Allergy and Clinical Immunology, Paller, the Northwestern Medicine chair of dermatology, together with Dr. Emma Guttman-Yassky of Mount Sinai Medical School [RRDi MAC Member], discovered that an arm of the immune system -- the Th17 pathway -- in these patients is way too active, and the higher its activity, the worse the disease severity....The drug Paller will test, secukinumab, has already been highly effective in psoriasis, a more common skin disorder with an increase in this Th17 pathway, leading to inflammation and scaling. And with Paller's new discovery, she thinks the drug could be even more helpful in ichthyosis because the overactive immune pathway was actually more strongly correlated with ichthyosis than with psoriasis." Research finally reveals reason for perplexing red skin disease Science Daily, September 20, 2016

The Rosacea X-Factor Syndrome is an interesting concept originated at a rosacea yahoo group sometime around the year 2000. The X-Factor is 'the factor of a regimen of treatment for rosacea that is not fully understood when rosacea is controlled in one person, but the same regimen doesn't work for another rosacean.' One factor to consider is understanding the placebo/nocebo effect which may explain why this phenomenon occurs. While one rosacean may report success in treating rosacea explaining their treatment in detail, another rosacean will try it and not find the same level of success. Why? What is the X-Factor? The X-Factor may be rooted in what causes rosacea or what you believe is the cause. Possibly your bias toward the treatment also factors in the placebo/nocebo effect which may explain it. There may be other reasons why a particular rosacea regimen for one rosacean that works to control rosacea will not work for another rosacean but for now the X-Factor is a good explanation to describe this phenomenon or syndrome. The King of the Soolantra threads is an example of the Rosacea X Factor who report that Soolantra is God's grace to rosacea sufferers and then there are those who say Soolantra doesn't work for them. Those who use Mirvaso are another example of the X factor with positive reports and the negative reports that indicate the syndrome. Trigger factors are included in the X-Factor, since what may trigger a rosacea flare-up in one rosacean may not trigger another rosacean. Trigger factors only MAY trigger a rosacea flare-up no matter who makes up the trigger factor list. One of the problems with the X-Factor is that there is the difficulty of defining rosacea and how rosacea is often misdiagnosed. When a physician says that you have rosacea (or one of the phenotypes [used to be called subtypes] ) this disease looks like so many other skin conditions that a rosacean may find later that it is SD, PF, PD, or demodectic rosacea. The disease has such a broad spectrum and looks way too much like acne, SD, lupus, PD, and a host of rosacea mimics. The point of all this is that when one is looking for a treatment for rosacea, assuming that the doctor is right about the diagnosis, and finds out way down the line that what is on the face is actually another skin disease or condition, the X-Factor goes into another realm, the Rosacea Twilight Zone. it really shows that we need research on this, and that is why this non profit organization was formed in the first place, to do just that. For more information, read Rosacea Research in Perspective of Idiopathic Diseases. As for treatment, you should first read the Gold Standard Treatment for Rosacea, and if this doesn't work for you, then read the post, When Rosacea Resists Standard Therapies. The real question is what is the X-Factor for you? The X-Factor is why treatment for rosacea is an individual thing. What works for one rosacean may not work for another. The X-Factor will not go away unless we find a cure for rosacea. Rosacea Research The Rosacea X-Factor is with us until we know more. What about researching rosacea? Understanding the Risk-benefit Ratio in Rosacea Research & Development will help. One other thing you can do is join the RRDi and help us find the cure. If you joined our cause and we reached 10K members, and each member donated one dollar, we could sponsor our own double blind, placebo controlled, peer reviewed clinical study on the X-Factor with the collaboration of the RRDi MAC (or we could research another subject!). Please join. Reply to this TopicThere is a reply to this topic button somewhere on the device you are reading this post. Subscribe to post.

"Blood-filled pimples are most commonly caused by a condition called cystic acne. Cystic acne occurs when facial hair follicles become clogged and fill with blood and pus, says Proactiv. The hormone androgen, which increases during the teen years, contributes to the formation of cystic acne, explains WebMD.....Cystic acne happens when a bacterial infection occurs deep in the skin. The infection causes large, red, painful bumps or nodules to form deep under the surface of the skin. The outermost layer of the nodule is filled with blood, with a layer of pus underneath. Cystic acne is hereditary and is most common in young men, although women get it as well, notes WebMD. Never attempt to pop blood-filled pimples caused by cystic acne, advises Proactiv. If the pimples are popped, the bacterial infection may spread to the rest of the face, causing further breakouts." reference.comAccording to Proactive, "Cystic acne, or any form of scarring acne, needs immediate attention by a dermatologist. A doctor will have the best solution for nodular acne treatment." The better part of wisdom would be to go back to your dermatologist and ask your questions about this. "Blood filled pimples should never be popped or squeezed and instead should be allowed to heal naturally. Opening the pimple before it has healed can spread bacteria to other areas of the skin, which can cause infection." LivestrongNurse Bridgid has an interesting article, Is that a Zit, Cyst, or Furuncle??, about cysts which you might find helpful. Health Central has others asking the same question, but you have to login to get the answers. Papule, Pustule, Pimple, Comedo, Lesion, Cyst & Abscess Explained

TheRed (see post #17) started a thread using 0.5% ivermectin cream and ended up using 1% ivermectin cream along with Acnil Rose (contains Azelaic Acid 15%) reporting that it cleared her skin.

Photo Damage is one of the theories. You may be on to something. Time will tell.

"The global market for rosacea therapeutics is expected to grow steadily during the forecast period 2016-2024, owing to rising awareness among people." "Research on how rosacea affects certain individuals is yet to yield any concrete answers. Currently, there is no cure for rosacea, however, through effective management, the symptoms can be managed." Rosacea Therapeutics Market: An Revolutionary innovation that redefines HC for Healthier Future, medGadget

Daily Star

According to Seeking Alpha, Soolantra increased by 36%. Most anecdotal reports are reporting success with this treatment with very few reporting no success. You may want to read anecdotal reports from RF or drugs.com.

One paper describes using probiotic therapy ((Bifidobacterium breve BR03, Lactobacillus salivarius)) along with Oracea for scalp rosacea. A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options Dermatologic Therapy, Volume 29, Issue 4, pages 249–251, July/August 2016 M. C. Fortuna, V. Garelli, G. Pranteda, F. Romaniello, M. Cardone, M. Carlesimo & A. Rossi

Peter Crouch, MD, a long time contributor in the rosacea forums has passed away on September 10, 2016. He was very helpful to rosacea sufferers. Dr. Crouch will be missed. On September 2 (post #4 in the thread he started in June), Dr Crouch posted for his last time at RF recommending another physician to get help for rosacea. Dr. Crouch was truly a very caring person. Swindon Advertiser

Ivermectin Cream Will Contribute Much to the Treatment of Patients with Rosacea: Interview with Dr Zoe Draelos by Caroline Helwick, American Health and Drug Benefits Dr. Draelos volunteers on the RRDi MAC.

Sincere story however, Sean promotes Shakeology.

Added sugar or saturated fat: Which is worse? MARY JO DILONARDO, Mother Nature Network The article cites sugar's role in weight gain and poor nutrition, a link between sugar and unhealthy cholesterol, heart disease and tooth decay. The RRDi has pointed out sugar's role in rosacea as a trigger for over ten years.

The RRDi is an Amazon Affiliate. By clicking below on the image and purchasing the item, the RRDi receives a small fee. Thanks. Please post your experience using this product in this thread. The RRDi has collected a number of cosmetics to consider in your search by using our affiliate store. Denise Wheat Graham demonstrates how Younique Touch Mineral Pressed Powder Foundation covers rosacea.