Guide

J.P. Morgan image courtesy of wikipedia "A powerful financier, banker, and philanthropist in the early 1900s, J.P. Morgan is admired for shaping much of our banking industry today. But like W.C. Fields, J.P. Morgan suffered from a swollen and bumpy nose due to his rosacea. Today, there are treatment options, like laser therapy, that can help correct the problem." The Celebrity Face of Rosacea, healthgrades Famous Rosaceans

Lisa Faulkner image courtesy of Lisa Faulkner The television star and celebrity chef, pictured above, was reportedly first diagnosed with rosacea in 2005 following the occurrence of red patches on her cheeks. She manages her condition by avoiding her personal triggers, including spicy foods and champagne, and uses acupuncture to keep calm and ward off stress, another rosacea trigger. Red Carpet, Red Face: Celebrities Talk About Their Rosacea, NRS Famous Rosaceans

Dita Von Teese image courtesy of wikipedia Striking beauty and porcelain white skin are what this contemporary icon is known for, but underneath her clear complexion was once a red flush of rosacea, which the performer reportedly battled with a visit to a dermatologist and oral and topical medical therapy. Red Carpet, Red Face: Celebrities Talk About Their Rosacea, NRS Famous Rosaceans

Rosacea isn't only a problem for modern times. It's believed that 17th century Dutch painter Rembrandt van Rijn was another famous face with rosacea. The diagnosis actually came centuries after his death. In 1997, a researcher from Georgetown University poured over Rembrandt's detailed 1659 self-portrait. He reported in the British medical journal The Lancet that the masterpiece painter had an enlarged nose, visible blood vessels, and pimples in many areas of the face — all signs of advanced rosacea. Famous Faces With Rosacea, everyday health enlarge "And finally for those who believe that rosacea is only a modern-day problem, they’re mistaken, because it is believed that 17th century Dutch painter Rembrandt van Ridjn suffered from rosacea. It seems hard to believe that he had rosacea because the diagnosis came out centuries after his death. A researcher from Georgetown University studied Rembrandt’s 1659 self-portrait. In 1997 he reported at The Lancet, a British medical journal that the painter had an enlarged nose, spider veins and acne like breakouts, which are all signs of subtypes 1, 2 and 3 rosacea." celebs with rosacea and what they can teach us, finca skin organics Famous Rosaceans

image courtesy of wikipedia "What did former President Bill Clinton have to blush about? We all know the answer to that delicate question! Like Princess Diana, Rosie O’Donnell and W.C. Fields, he also suffered from Rosacea." Dr. W. Gifford-Jones: An overlooked skin condition gets some attention, wickedlocal.com Famous Rosaceans

image courtesy of Wikipedia "The newly-hitched (and current Canadian tourist) Prince William and former US president Bill Clinton have something in common other than their first names. They join celebrities such as comedian W.C. Fields, actor Ricky Gervais and actress Sarah Michelle Geller of Buffy the Vampire Slayer fame (plus 45 million people worldwide) in having a facial skin condition that is both bothersome and unsightly. Called rosacea (pronounced roe/zay/sha), it's a chronic skin condition that can cause red and inflamed skin around the cheeks, nose and forehead." Red in the face Embarrassment, stares and discrimination plague those suffering from rosacea BY MARILYN LINTON, QMI AGENCY, Toronto Sun Famous Rosaceans

image courtesy of Wikipedia "The newly-hitched (and current Canadian tourist) Prince William and former US president Bill Clinton have something in common other than their first names. They join celebrities such as comedian W.C. Fields, actor Ricky Gervais and actress Sarah Michelle Geller of Buffy the Vampire Slayer fame (plus 45 million people worldwide) in having a facial skin condition that is both bothersome and unsightly. Called rosacea (pronounced roe/zay/sha), it's a chronic skin condition that can cause red and inflamed skin around the cheeks, nose and forehead." Red in the face Embarrassment, stares and discrimination plague those suffering from rosacea BY MARILYN LINTON, QMI AGENCY, Toronto Sun Famous Rosaceans

"Prince William has a condition called rosacea, which is characterized by a distinct redness in the cheeks. Early photos of the prince show he's had the condition for years." Yahoo News

"What do Bill Clinton and Prince Charles have in common? The answer: rosacea, a ruddy complexion that in some cases can mistakenly be attributed to a problem with alcohol." It's the rosacea, stupid: From Bill Clinton to Prince Charles, the red facial flushes caused by a debilitating skin condition By Alison Bowser, Daily Mail The NRS reports, "Among the most famous rosacea sufferers is former President Bill Clinton, whose doctors disclosed that he has this condition in The New York Times." For Millions With Rosacea 'The Eyes Also Have It', NRS Star Online Famous Rosaceans

Henry Charles Albert David (Prince Harry) suffers from rosacea according to vericoseveins.org which reports, "Prince Harry is the youngest son of Diana and Charles, so it is not surprising that he too suffers from rosacea and related facial redness." Royal Family of Facial Redness Famous Rosaceans

According to vericoseveins.org, Charles Philip Arthur George (Charles, Prince of Wales) suffers from rosacea and states, "The first husband of Princess Diana and the father of Prince William and Prince Harry, Charles is the longest-serving heir apparent in British history. Charles’s rosacea condition has been caught on camera multiple times and seems to be getting worse with increasing age." Royal Family of Facial Redness Famous Rosaceans

image courtesy of wikipedia According to everyday health, "The late Princess Diana also had the condition, according to the book Royal Fashion and Beauty Secret by Ann Chubb." According to Healthista, "Prince William could have inherited the condition from his late Mother, Princess Diana." "Rosacea and a princess, if you are suffering with rosacea you are not alone as Diana, Princess of Wales also suffered with the disease. Prince Charles suffers and Princess Diana suffered with rosacea as well as their son Prince Harry." ROSACEA AND A PRINCESS, Howard Baker, RN BSN, bereaonline.com Royal Family of Facial Redness, vericoseveins.org Famous Rosaceans

But it’s rosacea I’ve always dreaded - permanent facial redness with stinging, spots and pronounced visible facial blood vessels, which is treated with antibiotics but tends to recur. European Dermatology London’s founder and medical director Dr Stefanie Williams throws me a crumb of hope. “It is a myth that alcohol consumption causes rosacea,” she says. “Rosacea is a common chronic skin condition between 30 to 60 years, especially in fair-skinned women. Rosacea is caused by a genetic predisposition, not alcohol. However, in people with a genetic predisposition to rosacea, alcohol may trigger flare-ups.” Is Wine Your Skin's Deadliest Foe, Or Its Secret Weapon?, by ANNA BLOMEFIELD, Vogue More information on Alcohol and Rosacea

There is a difference between dust mites, demodex, scabies, and bed bugs . So what are the differences? While morphologically they are different we are concentating on the size in this post. Many may be confused about these four critters, so here are some facts: Dust mite image courtesy of Wikimedia Commons - Dermatophagoides farinae measures 0.2–0.3 mm (0.008–0.012 in) in length difficult to see with the naked eye Demodex Image courtesy of Wikimedia Commons- adult, D. folliculorum can measure 0.3–0.4 mm (0.012–0.016 in) in length and possess four pairs of short legs near its head and neck region, so they are are barely seen with naked eye. Scabies (Sarcoptes scabiei) Image courtesy of Wikimedia Commons - Females are 0.3–0.45 mm (0.012–0.018 in) long and 0.25–0.35 mm (0.0098–0.0138 in) wide, and males are just over half that size and may appear as tiny black dots to the naked eye Bed Bug Image courtesy of Wikimedia Commons - Adults grow to 4–5 mm (0.16–0.20 in) long and 1.5–3 mm (0.059–0.118 in) wide, so they can be seen easily with the naked eye. Conversions 1 Centimeter (cm) = 10 Millimeters (mm) 1 centimeter = 0.393701 inch 1 inch = 2.54 centimeters 1 millimeter is 10 times smaller than a centimeter. 1 millimeter (mm) = 1000 micrometers (μm) images courtesy Wikimedia Commons Examples 0.3 mm = Grain of Salt 1 mm = One sheet of paper 1.5 mm = Diameter of pin head 10 mm = Ten sheets of paper Micrometer A micrometer (symbol, μm - also called a micron) is 1000 times smaller than a millimeter ( or one millionth of a metre). Average Size of Demodex Compared with Dust Mite or Bed Bug "Using a confocal laser scanning in vivo microscope allowed determining the average size of Demodex mites. When determining the size of mites from 100 to 200 μm, it was believed that in this case Demodex brevis was observed, while the average length of the mite was 125 μm; from 200 to 400 μm – Demodex folliculorum with an average length of 293 μm. The average size of the width of Demodex mites was 24 μm." [1] Wikipedia reports that the d. folliculorum measures 0.3 - 0.4 mm which is an average of 0.35 mm. The Russian study mentioned in end note 1 reports the average length of 293 μm which is 0.293 mm, about the length of a grain of salt, but of course, thinner in width. So the demodex you can barely see with the naked eye (a microscope or dermoscopy facilitates an investigation better than the naked eye). The dust mite is more difficult to see with your naked eye and is barely smaller in size to the average demodex mite. The bed bug you can easily see with your naked eye and is the largest of the three critters. There is an article discussing dust mites and atopic dermatitis [2]. The scabies (Sarcoptes scabiei) mite may look like tiny black dots to the naked eye. [3] Better Viewing Demodex with a Microscope or Dermoscopy A cheap microscope can view demodex a lot better than using your naked eye. Dermatologist sometime use both a microscope in their office but usually use dermoscopy in their office exam of a patient. You too can purchase either device and view these critters yourself. Dermoscopy is using a device similar to the one below available at Amazon: 3GEN DL1 Epiluminescence Dermlite Dermatoscope Skiary Smartphone Dermatoscope Confocal Laser Scanning in Vivo Microscopy A Russian study concluded that the Confocal laser scanning in vivo microscopy was superior to using a skin scraping with a light microscope. [4] Etcetera Decreasing Demodex Density Count Improves Rosacea Why do demodex mites like human skin? Ward's Demodex in Situ Slide Conclusion So you should differentiate whether you are suffering from either demodex, dust mites, bed bugs or scabies. A dermatologist can determine if you are suffering from either one of these critters. All mite afflictions are treatable and respond well to treatment. In this forum rashes from bed bugs (are not a mite, are instead insects in the family Cimicidae) or dust mites are rarely mentioned, while scabies is rarely mentioned (except in this post and so far one other) and if you do have a rash from any of these (except demodex), you may be suffering from Atopic Dermatitis. Demodex mites are involved with demodectic rosacea. However, many have reported success treating demodectic rosacea with Soolantra, horse paste, the ZZ cream, Cliradex, Ovante, Ungex, and a number of other treatments. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. End Notes [1] Dermatol Reports. 2019 Jan 23; 11(1): 7675.Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mitesAlexey Kubanov, Yuliya Gallyamova, and Anzhela Kravchenko [2] Vitamin D, Dust Mites, and Atopic Dermatitis Korean study suggests a connection, Medpage Today [3] CDC, Biology, Parasites, Scabies Scabies Slideshow: Symptoms, Cause, and Treatments, WebMD Crotamiton, a prescription drug used to treat scabies has been reported to improve rosacea. [4] Russian Study on Demodex Mites and Rosacea Illuminating Confocal microscopy, most frequently confocal laser scanning microscopy (CLSM) or laser confocal scanning microscopy (LCSM), Wikipedia How does a confocal microscope work?, Emory University

Orbis Research has added Latest report on “Rosacea Medicine Market to Significant Growth Foreseen by 2022” by Manufacturers, Regions, Companies and Forecast up to 2022. Request a Sample Report: http://www.orbisresearch.com/contacts/request-sample/431635 The Global and Chinese Rosacea Medicine Market is being actively pursued by a substantial amount of key players across the globe. The market is caught major traction, especially in China which is the reason for the key insights presented in this report for China, along with the globe. The report has key insights on the global Rosacea Medicine Market for the clients who wish to broaden their spectrum in the market and expand their reach. Individuals interested in the report for purely academic purposes also have a substantial amount of data presented to suit their requirements. To Buy this Report for User License: http://www.orbisresearch.com/contact/purchase/431635 medGadget

FX2016-12: A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, VEHICLE-CONTROLLED STUDY TO EVALUAGE THE SAFETY AND EFFICACY OF XXXXX 1.5% TOPICAL XXXXX COMPARED TO VEHICLE IN THE TREATMENT OF FACIAL PAPULOPUSTULAR ROSACEA. - Clinical Trial Burke Pharmaceutical Research 3633 Central Ave., Suite I, Hot Springs, Arkansas 71913 T: (501) 620-4449 Burke Pharmaceutical Research is now enrolling participants in a clinical study that offers medication and exams to those affected from rosacea at no cost. To qualify for the program, the person must be 18 or older and have moderate to severe rosacea. Once qualified, they could receive a new foam medication and up to $300 compensation for their participation. "Burke Pharmaceutical Research has spent the past 10 years growing from a small clinical trials unit into a unique research facility with an impressive record. Their dedicated staff is proud that the company, known for its 'small town' atmosphere, ranks consistently among the highest in the nation with its enrollment into clinical trials and patient retention rates," states the press release. The office is located at 3633 Central Ave., Suite I, in Hot Springs, right next door to The Dermatology Clinic. Anyone who would like to sign up for the rosacea study may call 501-620-4449. If interested in learning more about the other programs that are available, view the full list online at http://www.burkepharmaceuticalresearch.com or http://www.facebook.com/burkeresearch. The Sentinel-Record

"There is evidence that polyphenols may be beneficial for the treatment of rosacea symptoms. Polyphenols appear to be most effective at reducing facial erythema and papule and pustule counts. However, studies included have significant methodological limitations and therefore large-scale, randomized, placebo-controlled trials are warranted to further assess the efficacy and safety of polyphenols in the treatment of rosacea." The Role of Polyphenols in Rosacea Treatment: A Systematic Review Saric Suzana, Clark Ashley K., Sivamani Raja K., Lio Peter A., and Lev-Tov Hadar A.. The Journal of Alternative and Complementary Medicine. June 2017

"Scope of this report: The report provides competitive pipeline landscape of Rosacea. The report provides the marketed drugs information including its sales, development activities and details of patent expiry. The report provides the insight of current and future market for Rosacea. " Rosacea Global API Manufacturers, Marketed and Phase III Drugs Landscape, 2017, medGadget

"Rosacea is a very common skin condition that causes a hot, sensitive rash to appear on the sufferer's body – typically on their face. It is thought to affect up to one in 10 people in the UK but, despite its prevalence, it remains shrouded in mystery. Here, we speak to Dr Stefanie Williams – dermatologist and medical director at Eudelo – to debunk some of the more common misconceptions surrounding the condition, which can often cause embarrassment, anxiety and low self-esteem." 10 rosacea myths that need to be debunked, By Jenny Cook, netdoctor

"Europe Rosacea Market and Competitive Landscape - 2017, provides comprehensive insights into Rosacea pipeline, epidemiology, market valuations, product sales, market forecast, product forecasts, and market shares. This study accurately estimates and forecast Rosacea market size and drug sales. This research also provides insights into Rosacea epidemiology and late stage pipeline." BusinessWire

"PDL can be used added to oral minocycline to reduce relapses among rosacea patients who are undergoing oral minocycline treatment." Pulsed Dye Laser Treatment Combined with Oral Minocycline Reduces Recurrence Rate of Rosacea. Ann Dermatol. 2017 Oct;29(5):543-547 Ko HS, Suh YJ, Byun JW, Choi GS, Shin J Image courtesy of Wikimedia Commons (The internal cavity of a Coherent Inc. model 740 dye laser is exposed during alignment of the optics)

Rosacea : A Chronic Inflammatory Disease (RRDi) Rosacea has been defined by many authorities and organizations and the list is quite extensive. Usually the consensus of all these authorities is that all the definitions include erythema. For some examples, read below: Rosacea Defined by Many Authorities Rosacea is a chronic and sometimes progressive disorder of the face, characterized by some or all of the following symptoms: Extremely sensitive facial skin with blushing, flushing, permanent redness, burning, stinging, swelling, papules, pustules, broken red capillary veins, red gritty eyes (which can lead to visual disturbances) and in more advanced cases, a disfiguring bulbous nose. Men and women of all ages can be affected, with over 415 million estimated rosacea sufferers worldwide. RRDi Welcome Page "Rosacea is probably a collection of many different diseases that are lumped together inappropriately." Zoe Diana Draelos, MD. • RRDi Welcome Page "Rosacea is a multifactorial, hyper-reactivity, vascular and neural based disease with a broad range of facial manifestations where normal vasodilation is greater and more persistent and involves an autoimmune component of microscopic amounts of extravasated plasma induce localized dermal inflammation that may induce repeated external triggers, vasodilation, telangiectasias, redness with eventual fibrosis and hypertrophic scarring of the dermis." Sandra Cremers, M.D., F.A.C.S., RRDi MAC Member • RRDi Welcome Page Rosacea is a polyethiologic chronic inflammatory disease with varying clinical manifestations. It is primarily a dermatologic disease, which often manifests in the eyes affecting eyelids, cornea and conjunctiva. The leading role in the pathological process belongs to disruption of regulatory mechanisms in the vascular, immune and nervous systems. It is accompanied by increased levels of metalloproteinases and vascular endothelial growth factor (VEGF). [1] Rosacea (roe-ZAY-she-uh) is a common skin condition that causes redness and visible blood vessels in your face. It may also produce small, red, pus-filled bumps. These signs and symptoms may flare up for weeks to months and then go away for a while. Rosacea can be mistaken for acne, other skin problems or natural ruddiness. [2] Rosacea (ro-ZAY-she-ah) is a long-term disease that causes reddened skin and pimples, usually on the face. It can also make skin thicker and cause eye problems. [3] Rosacea is a common chronic skin condition that usually only affects the face and eyes. Occasionally, the neck, chest, or other areas may be involved. Characterized by redness, pimples, and broken blood vessels, rosacea tends to begin after middle age (between the ages of 30 and 60). It is more common in fair-skinned people and women in menopause. [4] "Rosacea is a common chronic inflammatory cutaneous disease that can severely impair the quality of life. However, despite various treatment options, treatment results are often unsatisfactory, and relapses are common." [5] "Rosacea is a chronic inflammatory dermatosis characterized by remissions and flares." [6] FAQs Is this rosacea? Do more women or men have rosacea? Do Children Get Rosacea? What Is The World Wide Number Of Cases Of Rosacea? Differential Diagnosis Of Rosacea What Is The Rosacea Butterfly Or T Zone? Does rosacea spread beyond the facial region? What Causes Rosacea? What is involved in diagnosing rosacea? End Notes [1] Vestn Oftalmol. 2019;135(5. Vyp. 2):215-219 Mushroom keratoplasty in rosacea keratitis complicated by corneal perforation (a clinical case) Trufanov SV, Krakhmaleva DA, Zaitsev AV, Salovarova EP, Tekeeva LY, Budnikova EA [2] Rosacea, Mayo Clinic [3] Rosacea, NIH [4] Rosacea, John Hopkins University [5] Photodermatol Photoimmunol Photomed. 2020 Dec 11;: Gold photothermal therapy for refractory papulopustular rosacea: A case series. Park KY, Han HS, Park JW, Lee HW, Seo SJ [6] Long-term maintenance treatment of rosacea: experts' opinion

Foamix is sponsoring a clinical trial through the Yardley Dermatology Associates in PA if you suffer from Phenotype 4. To see if you may qualify, call Yardley Dermatology Associates/Dr. Richard Fried at 215-579-6155 ext. 28 or visit www.yardleyderm.com for more information today.

Galderma has announced its Galderma CareConnect Patient Savings Card Program that may save you money. You probably have many questions which are answered on the CareConnect web site. The program is offered to users for `any US Pharmacy that accepts manufacturer co-pay cards’. Galderma CareConnect is only available for commercially insured or uninsured patients. Patients who are enrolled in a government-run or government-sponsored healthcare plan with a pharmacy benefit are not eligible to use the Galderma CareConnect Patient Savings Card for many of the Galderma products. For More Information.

Center for Clinical Studies is looking for volunteers in a clinical trial who live near Houston, Texas. To learn more and to see if you qualify, call Center for Clinical Studies at 281-333- 2288, select option 2. More contact details on their facebook page – Center for Clinical Studies.