Guide

Persistent Erythema, Phenotype 2, is, perhaps, the most difficult phenotype to treat. Mirvaso and Rhofade are two treatments for phenotype 2. You should read the posts about Mirvaso and Rhofade. There have been reports of rebound with both, but particularly with Mirvaso (less rebound reports with Rhofade). "There are numerous treatment options available, including medical and/or laser, light and energy-based devices, that can ameliorate unwanted facial redness, telangiectasias, and superficial veins." [1] "Some recent research into the effectiveness of Soolantra has found that in addition to being proven (again) as a treatment for the papules and pustules of rosacea, it is also showing to be effective for the redness of rosacea." Soolantra works for a red face too, David Pascoe, Rosacea Support Botulinum toxin intradermal injection combined with broadband light [2] Brimonidine and Laser/Light-based Therapy Dual-frequency ultrasound (DFU) Carvedilol Endothelyol Non Prescription (store) Non Prescription (forum) Rosmarinic Acid, Gallic Acid, and Caffeic Acid Tranexamic acid solution Tranexamic acid (TXA) Intradermal Microinjections Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. End Notes [1] Clin Cosmet Investig Dermatol. 2021; 14: 601–614.Updates and Best Practices in the Management of Facial ErythemaJameson Loyal, Emily Carr, Rawaa Almukhtar, Mitchel P Goldman [2] "Botulinum toxin intradermal injection combined with broadband light has a definite therapeutic effect on the improvement of rosacea related erythema and flushing, which is better than simple broadband light, and has high safety. It is worthy of clinical promotion." A randomized, controlled, split-face study of Botulinum toxin and broadband light for the treatment of Erythemato telangiectatic rosacea

Rosacea Trial in Austin, Texas

softilly's treatment for erythematotelangiectatic rosacea:

If you’re suffering from rosacea, your doctor might simply tell you that there’s no real way to treat it and that you’ll probably have to deal with it for the rest of your life. But as with most other health conditions, the root cause of rosacea is almost certainly linked to your state of health in general, and particularly your diet and lifestyle. This article will seek to provide some simple, natural remedies to treat your rosacea to not only reduce the symptoms, but hopefully also prevent it from flaring up in the future. 5 Natural Remedies To Treat Rosacea, by Liivi Hess, The Alternative Daily

Botox jabs could offer a long-lasting solution for those who suffer the discomfort and embarrassing ‘blushing’ of rosacea. When tiny droplets of the wrinkle-busting nerve toxin are injected in diluted form into the forehead and cheeks, they have been found to reduce the redness which is the main symptom of the incurable skin disease. The breakthrough has been shown in early-stage trials to help all forms of the condition, including those characterised by acne-like spots on the face, and the severe skin-thickening form rhinophyma. Blush like Bridget Jones? A jab of Botox could help reduce redness and cut out acne-like spots, By Sara Malm In San Diego For Mail On Sunday, Daily Mail

Rosacea has for over 60 years has been treated with antibiotics. The current strategy is that antibiotics are not targeting microbes but are used for anti-inflammatory effects. However, there are a number of microbes that have been associated with rosacea (Candida Albicans, Chlamydophila pneumoniae, Demodex Mites, Helicobacter Pylori, Propionibacterium acnes, Staphylococcus epidermidis, and list keeps growing). With demodectic rosacea there are at least three microbes associated (Bacillus oleronius, Bartonella quintana, and Bacillus pumilus [see end notes 31, 68, and 70 in this article]). Antibiotic treatment is used for treating other diseases and it is noted that rosacea is improved in many cases as a side note. For example, patients treated with antibiotics for SIBO or IBS who also have rosacea note that rosacea is improved. A paper worth reading on the subject of gut flora discusses the 'metagenome' or the 'second genome' in the human gut which holds microbes containing more genes in the flora in the intestinal system than the rest of our bodies. The paper says, "This creates a huge dataset that has to be disentangled." [see end note 4] The paper discusses how understanding gut flora may be a key to understanding diseases.One study by Nature Publishing Group discusses how recent research suggests that humans might be divided into three types of gut bacteria: Bacteroides, Prevotella and Ruminococcus. This may lead to personalizing medical treatment based upon which type gut microbes you predominantly have. [see end note 5] "The three gut types can explain why the uptake of medicines and nutrients varies from person to person," reports Jeroen Raes, a bioinformatician at Vrije University. [see end note 6] This may develop into a new ‘biological fingerprint’ on the same level as blood types and tissue types. [see end note 7] This may lead to a 'gut type diet' (similar to the blood type diet].

A recent paper on "microbiome-based therapeutic strategies' states, "designing a geographically tailored therapeutic approach would need an in-depth understanding of how population and environmental parameters can affect the microbial communities and their metabolic potentials, which, we hope, may be attained in near future through construction of pan microbiome of human populations around the globe." The five major body habitats of the human microbiome, the Gut ( has the largest number of microbes and the greatest variety of species compared to other body habitats), Oral-cavity, Respiratory Tract, Skin (Studies suggested that diseases like atopic dermatitis, psoriasis, rosacea, acne etc. are often caused not because of pathogens but due to disruption in normal skin microbiota), and Urogenital Tract (UGT) shows "a gradual transition in the gross compositional structure along with a continual decrease in diversity of the microbiome, especially of the gut microbiome, as the human populations passed through three stages of subsistence like foraging, rural farming and industrialized urban western life." Front Microbiol. 2017; 8: 1162. Published online 2017 Jun 23. doi: 10.3389/fmicb.2017.01162 PMCID: PMC5481955 Geography, Ethnicity or Subsistence-Specific Variations in Human Microbiome Composition and Diversity Vinod K. Gupta, Sandip Paul, and Chitra Dutta Rosacea has been connected to the gut microbiome, but obviously the skin microbiome is something to consider, and we need more research on this. In an article discussing an infection with the Leishmania parasite "To my knowledge, this is the first case where anyone has shown that a pre-existing skin microbiome can influence the outcome of an infection or a disease," said Elizabeth Grice, co-senior author and assistant professor in the departments of Dermatology and Microbiology in Penn's Perelman School of Medicine. "This opens the door to many other avenues of research." [1] In rosacea 'microbiome-based therapeutic strategy' antibiotics have targeted bacteria for over sixty years. While this at times has proved beneficial in improving rosacea, antibiotics are wanting when it comes to a long term approach to treating rosacea due to antibiotic resistance as well as the long term side effects and risks. The other microbiome-based strategy has focused on reducing the demodex density count in rosacea. There may be other microbes to consider when treating rosacea, i.e., virus, archea, protozoa, helminths, or some other yet unknown microbe. These other microbes may not be considered worth more investigation than bacteria by most reputable investigators, it may be something that independent rosacea research sponsored by the RRDi could engage in if enough rosaceans united to sponsor such an investigation. How do you feel about such research into other microbes than bacteria? More Posts on This Subject Ammonia-oxidizing Bacteria (AOB) for Rosacea? Another New Article about the Gut-Brain-Skin Connection Baby You Can Drive My Gut BioMatrix Candid-X Characterization of the facial microbiome in twins discordant for rosacea. Diet and rosacea: the role of dietary change in the management of rosacea. Demodex and rosacea revisited. Demodex and the Gut? Do You Have a Gut Feeling About Your Rosacea? Everything You Need to Know About Your Skin Microbiome Gastrointestinal Rosacea [GR], aka, Gut Rosacea Jackson Laboratory and the Microbiome Microbiome Research Underway Microorganisms of the Human Microbiome Potential role of microorganisms in the pathogenesis of rosacea. Probiotic Approaches for the Treatment and Prevention of Ophthalmic Diseases Rosacea and its association with enteral microbiota in Korean females. Synbiotics for Rosacea? The Beauty of Dirty Skin The microbiome in dermatology. The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming. The skin microbiome: potential for novel diagnostic and therapeutic approaches to cutaneous disease. Three Gut Types Using the Skin Microbiome to Clear Rosacea Virus and Rosacea End Notes [1] A perturbed skin microbiome can be 'contagious' and promote inflammation, Science Daily

Many never touch alcohol but have rosacea. In certain people, overproduction of two inflammatory proteins and their subsequent interaction lead to the rise of a third protein that causes rosacea. Living With Rosacea, By Dr. Brian McDonough, CBSPhilly

"Especially during the summer, the initial redness of rosacea can easily be confused with a sunburn that lingers or doesn't go away," said Dr. John Wolf, chairman of dermatology at Baylor College of Medicine. "It's important for anyone who suspects they may have rosacea to see a dermatologist for diagnosis and appropriate medical therapy." The 'Sunburn' That Won't Go Away: Summer Tips for Controlling Rosacea, PRWeb, benzinga

We now allow guests to post feedback without registering an account in this forum. Scroll below about Active vs Inactive members. Voting Member The RRDi has now over 1000 charter members who have graciously joined providing contact information so that they can vote in our decision making of who serves on the board of directors every five years. If you want voting member status we require more than just an email address to vote. We understand that many of you do not want to provide such information so that is why we have setup the non voting member group discussed below. Non Voting Member Who Register an Account We have now opened up our membership to anyone who will provide an email address without giving us all the contact information. These new members who do not provide full contact information (only providing an email address) will not be able to vote for who serves on the board of directors, but will have posting privileges in the forums with access to the website. We hope to increase our membership since many are reluctant to join if they have to provide contact information. This way, only those who really want to vote will graciously provide such information if they want to, or, opt to be a member and be totally anonymous, with only providing an email address. By only providing an email address we are also allowing those to use their Apple or Facebook accounts to register an account with our forum, as well as Microsoft, and Google accounts. If you have any issues with registering an account, please use our support form or contact form and describe the issue so we can improve our registration process to make it as easy and user friendly as possible. By using one of the following sign in accounts below (Apple, Facebook, Microsoft, Google) it should be easy peasy (if not let us know). We are still working with Twitter and Linked in about this but you can use Apple, Facebook, Microsoft or Google login credentials with the RRDi it should be the easiest registration. Changing to a VOTING MEMBER If you join with just an email address you are a member, however you are NOT a VOTING MEMBER. If you are a non voting member and want to become a voting member read the paragraph above on Voting Member, that explains providing contact information allows you to vote. If you do indeed provide us with your contact information, i.e., first and last name, mailing address, phone, alternate email address in your PROFILE, and want to be considered a VOTING MEMBER then contact us and explain so we can change your account setting to a voting member. Changing to an ACTIVE MEMBER If you logged into your account and are not able to have access to parts of our website, you have become an INACTIVE MEMBER. Read this post on how to change back to an ACTIVE MEMBER with access to the rest of our website.

There are no known articles that have actually studied whether rosacea is contagious but any papers published about this question says that rosacea is not contagious. "Rosacea is not catching." [1] There are some communicable skin conditions and here is a list. A recent paper published by Cell Host & Microbe states, "In a new study, researchers at the University of Pennsylvania have shown for the first time that, not only can infection with the Leishmania parasite alter the skin microbiome of affected mice, but this altered microbial community can be passed to uninfected mice that share a cage with the infected animals." An article discussing this paper says, "To my knowledge, this is the first case where anyone has shown that a pre-existing skin microbiome can influence the outcome of an infection or a disease," said Elizabeth Grice, co-senior author and assistant professor in the departments of Dermatology and Microbiology in Penn's Perelman School of Medicine. "This opens the door to many other avenues of research." " Obviously we need better understanding of Microbiome-based therapeutic strategies. Demodectic Rosacea May Be Contagious Danners points out in post #10, "This question has been asked several times on this forum, with similar experiences described by the person posing the question. Doctors and online medical articles say these are not communicable diseases, however there are several, if not hundreds of anecdotal posts on acne.org, reddit and this forum that say otherwise." Are we discussing demodectic rosacea now? A point worth mentioning is that babies do not have demodex mites. So how do most humans have demodex mites on their skin if they are not transferred? So therefore, isn't it possible to 'catch' demodectic rosacea, which is a variant of rosacea? One paper on this subject states, "The transfer of Demodex mites between individuals appears to happen less frequently than the transfer of lice (Pediculus humanus), another human-associated arthropod species, as would be expected considering the more external habitat of lice in comparison with these pore-dwelling mites." [2] Another paper explains, "Conversely, if Demodex lack strong geographic structure, it suggests the movement of mites among humans must occur very frequently (perhaps even with social greeting rituals) and across large geographic distances." [3] This same source states the following about transmission of mites between humans: "Little is known about the transmission of mites among humans. Recent studies find that many symbiotic microbes are passed directly from mother to offspring during breast-feeding or during birth (especially if birth is vaginal), and dogs acquire their Demodex mites as nursing pups. In light of this, the same means of mite transmission seems possible in humans, supported by the fact that in one study, Demodex mites were found in 77% of nipple tissue from mastectomies. Yet that we found mites on all adults but only 70% of 18 year olds, suggests that perhaps mite colonization does not strictly occur vertically, from parent to child. These results are in line with earlier morphological (largely postmortem) studies in which mites were found to be more prevalent on adults than on children. Mites could be more ubiquitous on children than noted in postmortem studies or herein but at levels or in locations that make the mites difficult to detect even with the use of molecular approaches. One study of Demodex mites on Tokelau islanders found that mites were present on a greater number of children than on adults. These conflicting findings highlight our limited understanding of how and when mites move onto and among human bodies." [3] "Presumably, Demodex passes to newborns through close physical contact after birth; however, due to low sebum production, infants and children lack significant Demodex colonization....Infestation of both species is more common in males than in females, with males more heavily colonizing than females (23% vs 13%) and harboring more D. brevis than females (23% vs 9%)....The mites are transferred between hosts through contact of hair, eyebrows, and sebaceous glands on the nose." [4] "Although Demodex mites are considered to be highly host species-specific, cross-infections between humans and animals have been documented." [5] Logic concludes that demodectic rosacea may be contagious. However, why does one human (a) with rosacea who cohabits and consorts with another human (b) for many years not pass on rosacea to human (b) ? Obviously in such cases rosacea is not infecting human (b). So how can we prove beyond any doubt that demodectic rosacea may be contagious? A peer reviewed, double blind, placebo controlled clinical study should suffice to answer this question. How can this be done? Conclusion So, wouldn't it be nice if say ten thousand rosacea sufferers got together and each donated a dollar and then paid a physician to study this subject and write an article that nails the coffin on this? That brings us to a different subject, 'how do you bring together 10,000 rosacea sufferers together who can publish their own research on rosacea?' Can the RRDi do this? Why not join the RRDi and join in on this Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. dicussion? End Notes [1] British Skin Foundation, Rosacea [2] PNAS | December 29, 2015 | vol. 112 | no. 52 | 15963 Global divergence of the human follicle mite Demodex folliculorum: Persistent associations between hostancestry and mite lineages Michael F. Palopolia,, Daniel J. Fergusb, Samuel Minota, Dorothy T. Peia, W. Brian Simisond, Iria Fernandez-Silvad, Megan S. Thoemmesc, Robert R. Dunnc, and Michelle Trautweind [3] PLoS ONE 9(8): e106265 Ubiquity and Diversity of Human-Associated Demodex Mites Megan S. Thoemmes , Daniel J. Fergus, Julie Urban, Michelle Trautwein, Robert R. Dunn https://doi.org/10.1371/journal.pone.0106265 [4] Indian J Dermatol. 2014 Jan-Feb; 59(1): 60–66.doi: 10.4103/0019-5154.123498 PMCID: PMC3884930 Human Demodex Mite: The Versatile Mite of Dermatological Importance Parvaiz Anwar Rather and Iffat Hassan [5] Iran J Parasitol. 2017 Jan-Mar; 12(1): 12–21. PMCID: PMC5522688 Human Permanent Ectoparasites; Recent Advances on Biology and Clinical Significance of Demodex Mites: Narrative Review Article Dorota LITWIN, WenChieh CHEN, Ewa DZIKA, and Joanna KORYCIŃSKA For more information on the study of demodex mites, read Megan Thoemmes, PhD Student | Dunn Lab

"Red man syndrome is the most common adverse reaction to the drug vancomycin (Vancocin). It’s sometimes referred to as red neck syndrome. The name comes from the red rash that develops on the face, neck, and torso of affected people." Healthline

"The great thing about infrared saunas is that they can also help people who have rosacea, a condition that causes redness, and sometimes pus-filled bumps on your face. According to Spa Lé La’s website, infrared saunas offer the benefit of being anti-inflammatory, and therefore, it’s not irritating to the skin." This is how going to the spa can help with rosacea, pain, and stimulating collagen, by Alyssa Morin, Hello Giggles

Prescription costs for acne and rosacea medications for Medicare patients were higher from specialists compared with primary care physicians in family medicine or internal medicine, according to recently published study results in the Journal of the American Academy of Dermatology. Costs for acne, rosacea prescriptions for Medicare patients higher with specialists vs. PCPs, Healio Dermatology Zhang M, et al. J Am Acad Dermatol. 2017;doi:10/1016/j.jaad.2017.4.1127.

"I find myself struggling with a response. I know they think they’re giving me a compliment, so I don’t want to embarrass them by saying that I have a skin disease. Ask Amy: They think it’s a compliment when they mention my disease, By AMY DICKINSON | Tribune Content Agency, The Mercury News

"While the definitive cause of rosacea is unknown at this time, there are a few factors that are prevalent among those who suffer from this common skin condition." Twelve top tips for dealing with rosacea, Chris Barry, Starts at 60

Avenova is for dry eye syndrome. For more info click here.

"Over 30 million Americans share these chronic symptoms which may be due to blepharitis, meibomitis also known as meibomian gland dysfunction (MGD) often described more simply as dry eye syndrome...there is a new weapon called Avenova® that is designed for removal of microorganisms and debris that contribute to these conditions such as dry eye, MGD, blepharitis, Meibomitis and Stye." Avenova is made by NovaBay Pharmaceuticals Rebate – Pay no more than $35*. Rx Only

"Another possibility was that Raja’s eye problems stemmed from inflammation, Ngo thought; this could explain why both eyes were affected. Ocular rosacea, a type of the condition better known for causing red skin on the face, might make sense." When eye irritation is more than it seems at first glance, By ALLISON BOND, Stat

"Exercise can trigger a bout of flushing, facial redness and itchy skin - the key symptoms of rosacea - because it increases your body's core temperature. Indeed, 80 per cent of people in a survey by the National Rosacea Society said it aggravated theirs, particularly if it was high-intensity aerobic exercise. To retain the health benefits of exercise, the National Rosacea Society recommend sufferers do low- to medium-intensity exercise - like Pilates - instead. Similar to yoga, Pilates works by strengthening, stretching, and stabilising key muscles." Rosacea treatment: THIS form of exercise could significantly improve your skin, by LAUREN CLARK, Express

"I wish I could say I was the perfect skin regiment person. I work at night usually, so when I wake up it’s like noon. I will usually wash my face, just with water, to wake myself up. I do like to moisturize right off the bat. I’m very simple when it comes to my product. I’ll use Neutrogena, I’ve used Shiseido. Those are my favorite two that I vacillate between. And now I use Rhofade as part of my daily routine as a person who has had rosacea for years, and nothing ever really worked. (Chenoweth is a spokesperson for the brand.) With consistent use, this works. So I put on Nivea chapstick, I put on my lashes, and call it a day. On a daily basis, I don’t wear makeup—I let my skin breathe." Kristin Chenoweth On Her Skincare Secret, Fashion Tricks, And Her Dream Role, Celia Shatzman, Forbes

A Journal of Family Practice article says, "Using intention-to-treat analysis, permethrin 5% cream was as effective as metronidazole 0.05% gel and significantly superior to placebo at improving erythema (change from a baseline score of 2.60 to 1.34), papules (change from baseline count of 6.04 to 1.73), and pustules (change from baseline count of 2.30 to 0.56)." This same article reports, "Permethrin 5% cream is superior to metronidazole 0.75% gel and placebo in decreasing Demodex folliculorum, and is as effective as metronidazole 0.75% gel in treating erythema and papules." This may be a prescription or a non prescription treatment for rosacea. Ask your doctor. For more information read this post. Permethrin has been used on a pregnant patient. For more information. "Permethrin, sold under the brand name Nix among others, is a medication and insecticide." Wikipedia Permethrin is included in with the Anti-parasitic Prescription Agents used to treat rosacea.

A Journal of Family Practice article says, "Using intention-to-treat analysis, permethrin 5% cream was as effective as metronidazole 0.05% gel and significantly superior to placebo at improving erythema (change from a baseline score of 2.60 to 1.34), papules (change from baseline count of 6.04 to 1.73), and pustules (change from baseline count of 2.30 to 0.56)." This same article reports, "Permethrin 5% cream is superior to metronidazole 0.75% gel and placebo in decreasing Demodex folliculorum, and is as effective as metronidazole 0.75% gel in treating erythema and papules." For more information read this post.

Em270 from Canada, at RF, posted a link to Kate's Rosacea non prescription treatment for rosacea blog, permethrin 5% scabies, which lists a long list of over the counter treatments for your consideration. If anyone confirms this works for rosacea, please post in this thread. I can't find any product at the USA Amazon site that comes close to this treatment. If anyone does find something at Amazon, please post in this thread. Kate says she uses Quellada Lotion available in Australia. She says it is available outside of Australia as Kwellada-P or available at Amazon Canada, but no such item is available. U Michigan article PubMed article The prescription Permethrin 5% Cream is mentioned in the Journal of Family Practice article, which says, "Using intention-to-treat analysis, permethrin 5% cream was as effective as metronidazole 0.05% gel and significantly superior to placebo at improving erythema (change from a baseline score of 2.60 to 1.34), papules (change from baseline count of 6.04 to 1.73), and pustules (change from baseline count of 2.30 to 0.56)." This same article reports, "Permethrin 5% cream is superior to metronidazole 0.75% gel and placebo in decreasing Demodex folliculorum, and is as effective as metronidazole 0.75% gel in treating erythema and papules." More information. It is apparently odd that you can't purchase this product over the counter in the USA, however, according to this article you can purchase it on ebay. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

Until she was about 25, Chenoweth had never dealt with skin problems, so when she started experiencing bumpy, itchy redness on her face, she treated it with over-the-counter meds. "I tried all the wrong things, of course Cortisone, oils, you name it—anything over the counter I tried it." When she finally saw a dermatologist several years later, she received an instant diagnosis: rosacea. Since then she's tried almost every remedy out there to keep her inflammation at bay, recently settling on a solution that just gained FDA approval, RHOFADE, for which Chenoweth is now the celebrity ambassador. "My redness has gone way down along with the bumps, itchiness, and this has been week four. I use it right after my moisturizer and it keeps my redness in check all day long." Yes, Windy Weather Can Trigger Rosacea—and So Can These 6 Other Things Grammy- and Tony-winning star Kristin Chenoweth opens up about her battles with rosacea—here's what you need to know about what triggers it, and how you can treat this pesky skin condition. BY JENN SINRICH, Reader's digest