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Guide

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  1. According to an article by Fiscal Standard, "Paratek Pharmaceuticals, Inc. (Partake),  formerly Transcept Pharmaceuticals, Inc. is a pharmaceutical company focused on the development and commercialization of antibacterial therapeutics based upon tetracycline chemistry." The article then mentions the following: 

     "Sarecycline is designed for use in the treatment of acne and rosacea."  This article further states, "The Company’s sarecycline is a Phase III antibacterial product candidate and was previously known as WC3035."

  2. A recent article has brought back the common question many rosacea sufferers ask: 

    Is Rosacea Caused by Nurture or Nature?

    According to an article published in 2015, referred to by these news wire sources, the answer is probably a 50-50%. Here is the list of articles published referring to this subject: 

    UV SAFETY MONTH: ROSACEA, ENDOMETRIOSIS, FIBROMYALGIA, HIGH BLOOD PRESSURE, AND ALLERGIES
    Medical Information Online, July 4, 2016

    Rosacea risk linked to genes, obesity, heart disease, and sun exposure
    By: Devon Andre | Skin Health | Wednesday, June 01, 2016 - 04:00 PM

    ROSACEA RISK LINKED TO GENES, OBESITY, HEART DISEASE, AND SUN EXPOSURE
    Headline News, HealthDate: 02.06.2016.

    Rosacea Caused Half by Nature, Half by Lifestyle: Study
    US News, Sept. 9, 2015

    Rosacea Caused Half by Nature, Half by Lifestyle: Study
    By Alan Mozes, HealthDay Reporter, Sept 9, 2015

    Rosacea Caused Half by Nature, Half by Lifestyle: Study
    Drugs.com, Sept 9, 2015

  3. Honevo Rosacea

    Honey to the Rescue for Rosacea Patients

    Honevo, a product composed of 90 percent medical grade kanuka honey and 10 percent glycerin, demonstrated efficacy as a rosacea treatment in a blinded, randomized clinical trial, the results of which were published in BMJ Open.

    During the trial, participants applied Honevo or cetomacrogol — a non-ionic moisturizing cream used by the control group — twice a day for eight weeks.

    At the trial’s conclusion, 34.3 percent of the participants in the Honevo group and 17.4 percent of those in the control group showed improvement of greater than or equal to 2 or more on the Investigator Global Assessment of Rosacea Severity Score. However, patients’ self-reports on a dermatology quality-of-life index and on the current severity of symptoms showed no difference in improvement between weeks two and eight. That may suggest some measurement tools need further refinement in future studies, researchers say. 
    MD NEWS, By: Michael Ferguson
    Friday, July 01, 2016 

    An article published in Dermatology Times says that "Honey may improve rosacea severity" and referred to an article published in the British Medical Journal Open about a product, Honevo Rosacea, and concludes, "Honevo is an effective treatment for rosacea." [1]

    Honevo Rosacea is 100% natural and contains just 2 ingredients: pharmaceutical-grade kanuka honey and glycerin manufactured by HoneyLab LTD in New Zealand. 

    If you have used this treatment please find the green reply button and comment. 

    End Notes

    [1] Honey may improve rosacea severity

     

  4. botox-cosmetic-100-units-vial.jpg.8239a2

    "Botulinum toxin has been used to treat persistent erythema and flushing in rosacea for several years."
    Botulinum Toxin: An Effective Treatment for Flushing and Persistent Erythema in Rosacea

    Botulinum Toxin for the Treatment of Refractory Erythema and Flushing of Rosacea
    Park K.Y.a · Hyun M.Y.a · Jeong S.Y.b · Kim B.J.a · Kim M.N.a · Hong C.K.a 
    Department of Dermatology, Chung-Ang University College of Medicine, and GoodDay Skin and Laser Clinic, Seoul, South Korea

    Botulin Toxin Use in Rosacea and Facial Flushing Treatment.
    Open Access Maced J Med Sci. 2019 Sep 30;7(18):2985-2987
    Scala J, Vojvodic A, Vojvodic P, Vlaskovic-Jovicevic T, Peric-Hajzler Z, Matovic D, Dimitrijevic S, Vojvodic J, Sijan G, Stepic N, Wollina U, Tirant M, Thuong NV, Fioranelli M, Lotti T

  5. EscherichiaColi_NIAID.jpg
    EscherichiaColi Image Wikipedia Commons

    "Nonpathogenic E. coli strain Nissle 1917, also known as Mutaflor, and E. coli O83:K24:H31 (known as Colinfant) are used as probiotic agents in medicine, mainly for the treatment of various gastroenterological diseases, including inflammatory bowel disease." Wikipedia

    "RESULTS: Eighty-nine percent of the patients with acne, papular-pustular rosacea and seborrhoic dermatitis responded to E. coli Nissle therapy with significant amelioration or complete recovery in contrast to 56% in the control arm (P < 0.01). Accordingly, in the E. coli Nissle treated patients life quality improved significantly (P < 0.01), and adverse events were not recorded. "
    World J Gastroenterol. 2016 Jun 21;22(23):5415-21. doi: 10.3748/wjg.v22.i23.5415.
    Intestinal-borne dermatoses significantly improved by oral application of Escherichia coli Nissle 1917.
    Manzhalii E, Hornuss D, Stremmel W.

     

  6. "We report a unique case of facial erythema of rosacea that responded to brimonidine gel with effective blanching for two years until the patient developed a paradoxical erythema reaction. This is an adverse reaction physicians should be aware of with continued prescription of brimonidine gel for their rosacea patients."

    Paradoxical Erythema Reaction of Long-term Topical Brimonidine Gel for the Treatment of Facial Erythema of Rosacea
    June 2016 | Volume 15 | Issue 6 | Case Report | 763 | Copyright © 2016

    Erin Lowe, MSIV and Scott Lim, DO

     

    jdd-acne-rosacea.jpg

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