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    We are rosaceans and this is a grassroots rosacea non profit organization. The entire board of directors are rosacea sufferers. Compare that with the other non profit rosacea organizations, run by NON rosaceans. We now allow guests to post here without registering an account.  

    We have an Invision Community public forum. A public forum allows the public to view the posts but only members can post (registering an account with your email is required). What is odd is that this format, while older than the social media platforms, i.e., Reddit, Facebook, Instagram, Twitter, etc., requires no more than what the social media platforms require, an email address. Maybe we lack a mobile app?  We are working on it with a beta version (read below). 

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    You may enter the Public Invision Community Forum. There is a beta version mobile app for Android and for Apple devices with a beta iOS version available!

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    Public Forum

    In a PUBLIC RRDi forum ALL posts are public and can be read whether you join or not. You may access the public forum url here: 

    https://irosacea.org/forums/

    We also have a Tapatalk Private Forum available (scroll below for more information). Private forums are just that, you cannot view the posts unless you join (the public can NOT view the posts)

    Tapatalk Enabled (private forum)

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    Tapatalk App
    The RRDi member forum, a public group, used to be available using the Tapatalk app which you can download from the App Store or Google Playstore.  The Tapatalk app ONLY works for our private rosaceans forum. 

    Currently the Tapatalk app (Version 1.6.6 ) for our public forum using Invision Community Version 4.5.1 is not compatible so we have turned it OFF. We await whether Tapatalk will support the latest version of the Invision Community platform for our public forum. You can read more about the Tapatalk PRIVATE rosaceans forum below: 

    Private Tapatalk Rosaceans Group
    The RRDi is affiliated with Tapatalk and is sponsoring a PRIVATE Rosaceans  [rosaceans are rosacea sufferers] Tapatalk forum free for users which is a private group. If you are not familiar with the difference between a private member forum and a PUBLIC forum, the posts in a private forum are only read if you join. Here is the official announcement about our Rosaceans Tapatalk Private Forum which explains an option about Tapatalk Gold Points (not required but available for your consideration). You may access the private rosaceans group here:

    https://rosaceans.org

    You are welcome to join either or both of our two member forums if you suffer from rosacea.  We will try the private Tapatalk forum for a year and if it is not popular we will probably drop it. So it is up to you whether having a private Rosaceans group is mo'betta than our Invision Community public forum which you can still use the Tapatalk application for our public Tapatalk member forum and our private group. The private Tapatalk is totally run on Tapatalk servers and has no issues using Tapatalk.  

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  • Posts

    • The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea? Dermatol Ther (Heidelb). 2020 Oct 23;: Authors: Forton FMN Abstract Rosacea is a common facial dermatosis but its definition and classification are still unclear, especially in terms of its links with demodicosis. Triggers of rosacea (ultraviolet light, heat, spicy foods, alcohol, stress, microbes) are currently considered to induce a cascading innate and then adaptive immune response that gets out of control. Recent histological and biochemical studies support the concept that this inflammatory response is a continuum, already present from the onset of the disease, even when no clinical signs of inflammation are visible. The Demodex mite is beginning to be accepted as one of the triggers of this inflammatory cascade, and its proliferation as a marker of rosacea; moreover, the papulopustules of rosacea can be effectively treated with topical acaricidal agents. Demodex proliferation appears to be a continuum process in rosacea, and may not be clinically visible at the onset of the disease. Molecular studies suggest that Demodex may induce tolerogenic dendritic cells and collaborate with vascular endothelial growth factor (VEGF) to induce T cell exhaustion and favor its own proliferation. These interactions among VEGF, Demodex, and immunity need to be explored further and the nosology of rosacea adapted accordingly. However, treating early rosacea, with only clinically visible vascular symptoms, with an acaricide may decrease early inflammation, limit potential flare-ups following laser treatment, and prevent the ultimate development of the papulopustules of rosacea. The effectiveness of this approach needs to be confirmed by prospective controlled clinical trials with long-term follow-up. Currently, the evidence suggests that patients with only vascular symptoms of rosacea should be carefully examined for the presence of follicular scales as signs of Demodex overgrowth or pityriasis folliculorum so that these patients, at least, can be treated early with an acaricidal cream. PMID: 33095403 [PubMed - as supplied by publisher] {url} = URL to article More in Demodectic Rosacea
    • "Fake news" in dermatology. Results from an observational, cross-sectional study. Int J Dermatol. 2020 Oct 23;: Authors: Iglesias-Puzas Á, Conde-Taboada A, Aranegui-Arteaga B, López-Bran E Abstract BACKGROUND: Social networks have become a means for disseminating information on health-related matters. OBJECTIVE: Describe the characteristics and analyze the accuracy of the dermatology content that is most often shared on the most popular social networks. MATERIALS AND METHODS: The content most often shared on social networks (Facebook, Pinterest, Twitter, and Reddit) between March 2019 and March 2020 was analyzed using the keywords: acne, alopecia/hair loss, psoriasis, eczema, melanoma, skin cancer, rash, and rosacea. The total number of interactions, skin disease, topic, and origin was collected from each of the records. The content was analyzed and was categorized as precise, confusing, or imprecise based on the scientific evidence available. RESULTS: A total of 385 websites were included. About 44.7% of the shared content was rated as imprecise, 20% as confusing, and 35.3% as precise. The records classified as imprecise obtained a higher mean number of interactions (P < 0.05). No differences were found in terms of the level of certainty and the dermatosis studied, whereas they did exist in relation to their topic and origin (P < 0.001). Of the contents classified as imprecise, the most frequent topic and origin were "alternative medicines" and "individual opinions, articles not affiliated with health institutions, nor peer reviewed," respectively. CONCLUSIONS: The majority of the contents often shared on social networks are below acceptable quality standards. Strategies are needed to discredit imprecise information and promote the dissemination of evidence-based dermatology information. PMID: 33095467 [PubMed - as supplied by publisher] {url} = URL to article
    • Volunteer Beta Testers Needed! Note: We have applied our community forum with Invision Community to list us under EDUCATION and we are still awaiting approval. As soon as we have been approved we will announce it and you should see the RRDi Member Forum listed along with the others.  We are pleased to announce that a new mobile app is available in beta version for Android (for Apple devices using iOS you need to scroll further down). You can find it on the Google Play store. It is the Invision COMMUNITIES app (not the Invision Community app which is for admins ONLY). Ditto, confusing, so, hopefully you won't download the wrong one. Here is a screen shot in the Google Play Store which is the second one called Invision COMMUNITIES:  We have listed our community, the RRDi, and you should be able to find it once we are listed in the beta version. Please let us know your experience with this new app on your mobile device?   The iOS version is still in beta testing. You can volunteer and be a beta tester if you follow the steps: 
    • The Pro-Differentiation Effect of Doxycycline on Human SZ95 Sebocytes. Dermatology. 2020 Oct 22;:1-5 Authors: Zouboulis CC, Ní Raghallaigh S, Schmitz G, Powell FC Abstract BACKGROUND: Despite their widespread clinical use in both acne vulgaris and rosacea, the effects of tetracyclines on sebocytes have not been investigated until now. Sebaceous glands are central to the pathogenesis of acne and may be important in the development of rosacea. OBJECTIVE: The aim of this study was to assess the effects of doxycycline on the immortalized SZ95 sebaceous gland cell line as a model for understanding possible effectiveness on the sebaceous glands in vivo. METHODS: The effects of doxycycline on SZ95 sebocyte numbers, viability, and lipid content as well as its effects on the mRNA levels of peroxisome proliferator-activated receptors α and γ, in comparison to the peroxisome proliferator-activated receptor γ agonist troglitazone, were investigated. RESULTS: Doxycycline reduced the cell number and increased the lipid content of SZ95 sebocytes in vitro after 2 days of treatment. These doxycycline effects may be explained by an upregulation of peroxisome proliferator-activated receptor γ mRNA levels at 12 and 24 h, whereas troglitazone already upregulated peroxisome proliferator-activated receptor γ levels after 6 h. Both compounds did not influence peroxisome proliferator-activated receptor α mRNA levels. CONCLUSION: These new findings illustrate a previously unknown effect of doxycycline on sebocytes, which may be relevant to their modulation of disorders of the pilosebaceous unit, such as acne vulgaris and rosacea. PMID: 33091909 [PubMed - as supplied by publisher] {url} = URL to article
    • Granulomatous Rosacea in Korean Patients: Diagnosis Based on Combining Clinical and Histological Findings. Dermatology. 2020 Oct 22;:1-5 Authors: Yang JH, Cho SI, Suh DH Abstract BACKGROUND: Granulomatous rosacea (GR) is a rare inflammatory skin disease, which is considered a variant of rosacea, apart from other types of rosacea. OBJECTIVE: This study aimed to summarize the characteristics of Korean patients diagnosed with GR by combining clinical and histological findings. METHODS: Fifteen cases, both clinically and histologically consistent with GR, were selected and were subsequently analyzed to describe clinical and histological characteristics. RESULTS: A total of 20 patients showed granulomatous infiltration in skin biopsies, but only 15 of them were clinically consistent with GR. Five patients who showed granulomatous inflammation were clinically consistent with erythematotelangiectatic or papulopustular rosacea. Among 15 patients, 13 (86.7%) were female and 2 (13.3%) were male. The most frequently involved area was the cheek, and none of the patients showed extrafacial lesions. There seems to be a possibility that treatment duration may be associated with the treatment response. CONCLUSIONS: This study confirms clinical characteristics of GR based on the diagnosis combining both clinical and histological findings. PMID: 33091912 [PubMed - as supplied by publisher] {url} = URL to article
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