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[Acantholytic rosacea of the forehead and scalp in a patient with Hailey-Hailey disease].

Ann Dermatol Venereol. 2012 Oct;139(10):626-30

Authors: Mohr M, Kanter P, Cribier B, Lipsker D

Abstract
BACKGROUND: Rosacea is a common dermatosis that can involve the bald area of the scalp. We report the case of a man presenting clinical symptoms of rosacea of the forehead and the scalp, but with a histological picture of familial chronic benign pemphigus.
PATIENTS AND METHODS: A 47-year-old man with a history of Hailey-Hailey disease had been presenting facial dermatosis for 5 years. The clinical features were erythema with pustules and scales located on the mid-forehead and the androgenic bald area of the frontal scalp. The histological aspect of the skin biopsy showed suprabasilar clefting and ancantholysis at all levels of the epidermis and sparse perivascular infiltrate. Direct immunofluorescence was negative. These findings were typical of Hailey-Hailey disease. Based on clinical findings, and without taking account of the skin biopsy results, treatment with doxycycline and a topical antifungal was administered for 3 months, leading to remission of symptoms.
DISCUSSION: The site of rosacea on the bald area of the scalp in males is described in the literature, and when present, is probably enhanced by exposure to UV radiation. In this patient, the histological features were interpreted as histopathologically equivalent to Köbner phenomenon.

PMID: 23122375 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/PubMed/23122375?dopt=Abstract = URL to article