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Isotretinoin for the Treatment of Granulomatous Rosacea: Case Report and Review of the Literature.

J Cutan Med Surg. 2012 Dec 1;16(6):438-441

Authors: Rallis E, Korfitis C

Abstract
Background:Granulomatous rosacea is considered a clinical variant of rosacea and is characterized by hard yellow, brown, red or flesh-colored cutaneous papules or nodules that may be severe and may lead to scarring. The lesions typically appear on the cheeks and periorificial lesions; they are monomorphic in each patient and sit on relatively normal-appearing skin. The diagnosis should be established by excluding other granulomatous disorders and rosacea-like eruptions such as sarcoidosis, tuberculosis, and lupus miliaris disseminatus faciei. The clinical course is chronic and unpredictable, and management can be very difficult.Case Report:We report the case of a 28-year-old female with granulomatous rosacea who responded successfully to oral isotretinoin. No recurrence was noticed 6 months after the completion of treatment.

PMID: 23149202 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/PubMed/23149202?dopt=Abstract = URL to article