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Dermadexin


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Dermadexin (also known as Pruridexin or Helioclin® Dermatitis SD Cream) is a topical treatment for dermatitis and seborrhoeic dermatitis developed by Astion Pharma with a unique mechanism of action using a Fatty acid amide hydrolase (FAAH) inhibitor and a NF-kappa B (NF-kB) inhibitor designated as pyridine-3-carboxamide glyceryl monocaprylate (P3CGM), which has an excellent topical safety profile demonstrating a broad range in pre-clinical studies. [1]

It was announced in August 2015 that the FDA accepted 510(k) submission for Dermadexin. [2]

There is now available an over the counter topical, Astion Face Cure (active ingredient Dermadexin), available at Amazon UK or on the Astion Pharma website.  

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Astion Face Cure contains the active ingredient Dermadexin [Pruridexin] and the inactive ingredients water, liquid paraffin, cetostearyl alcohol, glycerol, niacinamide, sodium cetostearyl sulphate, glyceryl monocaprylate and benzyl alcohol. 

Anecdotal Reports 

There are at least a couple of positive reports of using the Astion Face Cure, Boris started a thread on this, and post no 141 by freixinet

End Notes 

[1] Dermadexin Executive Summary

[2] FDA Accepts Dermadexin 510(k) Submission, Aug 6th, 2015, Medesthetics

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