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Competing endogenous RNA May Play a Key Role in the Genetic Cause of Rosacea Theory


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320px-MiRNA.svg.png micro RNAS courtesy of Wikimedia Commons

"Hundreds of publications have described the influence of ceRNA regulation in normal and disease cells, but ceRNA regulation and its effects continue to be debated in scientific circles." [1] 

Competing endogenous RNA (ceRNA) may have implications in the genetic theory on the cause of rosacea.  

"The exact molecular mechanisms of rosacea are unclear; however, this disorder is expected to be the result of a combination of several causes with genetic predisposition....In conclusion, this is the first study to identify the ceRNA network in rosacea....The lncRNAs and mRNAs identified in our study may play key roles in rosacea development....More in-depth researches are needed to better characterize the lncRNAs and mRNAs in rosacea." [2]

More Research on Competing endogenous RNA (ceRNA) Needed 

Do you want more research on this for rosacea?  Could a non profit rosacea patient advocacy grassroots organization collect donations and sponsor such an investigation?  Could 10K members each donate ONE DOLLAR to do this?  

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End Notes 

[1] Competing endogenous RNA, Wikipedia

[2] Biomed Res Int. 2020;2020:9705950 Full Text
Identification of Long Noncoding RNA Associated ceRNA Networks in Rosacea.
Wang L, Lu R, Wang Y, Wang X, Hao D, Wen X, Li Y, Zeng M, Jiang X



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