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Licochalcone A for Rosacea

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Chalcone, the structural backbone of chalconoids*

An article discussing the pharmacological properties of chalcones had this to say about rosacea: 

"A subsequent study on 33 rosacea patients showed that the skin care products with licochalcone A are compatible with the standard topical treatment of the disease." [1]

"Licochalcone A is a chalconoid, a type of natural phenol. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It shows antimalarial, anticancer, antibacterial and antiviral (specifically against influenza neuraminidase) properties in vitro." [2]

End Notes

*image courtesy of Wikimedia Commons

[1] Front Pharmacol. 2020; 11: 592654.
Published online 2021 Jan 18. doi: 10.3389/fphar.2020.592654
PMCID: PMC7849684
PMID: 33536909
Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence
Bahare Salehi, Cristina Quispe, 2 Imane Chamkhi, Nasreddine El Omari, Abdelaali Balahbib, Javad Sharifi-Rad, Abdelhakim Bouyahya, Muhammad Akram, Mehwish Iqbal, Anca Oana Docea, Constantin Caruntu, Gerardo Leyva-Gómez, Abhijit Dey, Miquel Martorell, Daniela Calina, Víctor López, Francisco Les 

[2] Licochalcone A, Wikipedia

Topicals that contain Licochalcone A

Eucerin Redness Relief Day Lotion

Chalcone Over the Counter Oral Treatments

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