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Face-to-face with anti-inflammatory therapy for rosacea.

Exp Dermatol. 2014 Mar 29;

Authors: Salzer S, Ruzicka T, Schauber J

Abstract
In the past, our understanding of rosacea has been inadequate and limited to descriptions of factors that exacerbate and improve the disease. While the pathophysiology of rosacea is complex and multifactorial, cathelicidin peptides have emerged as key players in the pathogenesis of this common dermatological disorder. This article correlates recent findings in abnormal cathelicidin production and proteolytic processing in rosacea with therapeutic actions of current treatment options and, in this way, highlights potential points of intervention for the development of efficient therapeutic alternatives. This article is protected by copyright. All rights reserved.

PMID: 24684602 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24684602?dopt=Abstract = URL to article