PubMed RSS Feed - -The effect of 577-nm pro-yellow laser on demodex density in patients with rosacea

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J Cosmet Dermatol. 2021 Mar 20. doi: 10.1111/jocd.14085. Online ahead of print.

ABSTRACT

AIMS: The pro-yellow laser is a yellow light wavelength (577-nm) laser system. Rosacea is a chronic inflammatory disorder that occurs with facial flushing, erythema, papules, pustules, and telangiectasia. Demodex parasites (Demodex folliculorum and brevis) also play a role in the pathogenesis of rosacea. The aim of our study is to evaluate the effect of pro-yellow laser on demodex density (Dd) in patients with rosacea.

METHODS: This retrospective study was planned for the patients with rosacea whose demodex mite densities were examined and treated with pro-yellow laser and were evaluated between 2019 and 2020 in the cosmetology unit. The laser light was applied at a dose of 20 j / cm² in the scanner mode (The 80% coverage) in all the patients. The demodex density per cm² was routinely evaluated before the treatment, and the demodex density values in the fourth week after the treatment were recorded from the patients' files.

RESULTS: There were 27 females (79.4%) and 7 males (20.6%) evaluated in the study. While the demodex density was 18.1 ± 10.7 (min: 0 - max: 48, Q1:12 - Q3:22) per cm2 before the pro-yellow laser treatment in the cases, the demodex density was 10.2 ± 7.9 (min: 0 - max: 30, Q1:4.75 - Q3:12) per cm2 in the fourth week after the treatment. After the pro-yellow laser treatment, the demodex intensity decreased significantly compared to before the laser treatment (p = 0.001). There was no significant correlation between the decrease in the density of the demodex mite and the success of the treatment (p = 0.46).

CONCLUSION: This is the first study in the literature investigating the change in demodex density in rosacea patients treated with pro-yellow laser therapy. In this study, it was shown that pro-yellow laser treatment is effective in reducing the density of demodex.

PMID:33742514 | DOI:10.1111/jocd.14085

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