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Comparative Efficacy of Intense Pulsed Light for Different Erythema Associated with Rosacea.

J Cosmet Laser Ther. 2014 Aug 25;:1-18

Authors: Liu J, Liu J, Ren Y, Li B, Lu S

Abstract Objective: To compare the efficacy of IPL (540-950nm) in treating different erythema associated with rosacea. Methods: Thirty-two patients with erythematotelangiectatic rosacea (ETR, n=16) and papulopustular rosacea (PPR, n=16) were recruited. Three treatments of IPL (540-950nm) were administered on the face at 3-weeks intervals. Clinical improvement in erythema was independently assessed by two dermatologists using a quartile grading scale [0, ≤25% improvement (poor); 1, 26-50% improvement (fair); 2, 51-75% improvement (good); 3, 76-100% improvement (excellent)]. Patient satisfaction was evaluated using a 10-point visual analogue scale (VAS: 0, lowest; 10, highest). Results: Thirty patients were in this study. All patients showed improvement in erythema after three sessions of IPL (540-950nm) treatment. Based on physician assessment the overall clinical improvement in PPR group was significantly higher (mean±SD: PPR group 2.167±0.748 vs. ETR group 1.400±0.541; P=0.003) and patient satisfaction was also higher in PPR group (mean±SD; PPR group 6.867±1.457 vs.ETR group 5.600±1.502; P=0.026). The proportion of patients showing >75% clinical improvement among PPR group was also higher than that among ETR group (5/15 and 0/15 respectively, P =0.021). Side-effects were minimal and transient (erythema and/or oedema) for patients. Conclusions: IPL(540-950nm) is a safe and effective treatment of rosacea-associated erythema, especially for perilesional erythema.

PMID: 25151911 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25151911?dopt=Abstract = URL to article

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