Azelaic Acid & Dihydroavenanthramide D for Rosacea

[Guide]

"Dihydroavenanthramide D (DHAvD) is a synthetic analog to naturally occurring avenanthramide, which is the active component in oats." [1]

Dihydroavenanthramide D has been shown to reduce itching, [2] inhibits mast cell degranulation and exhibits anti-inflammatory effects. [3]

Now Dihydroavenanthramide D along with Azelaic Acid has been shown to be "a valid therapeutic option for mild/moderate inflammatory rosacea." [4]

End Notes

[1] Dihydroavenanthramide D prevents UV-irradiated generation of reactive oxygen species and expression of matrix metalloproteinase-1 and -3 in human dermal fibroblasts

[2] Dihydroavenanthramide D for Anti-irritant and Anti-itch

[3] Dihydroavenanthramide D inhibits mast cell degranulation and exhibits anti-inflammatory effects through the activation of neurokinin-1 receptor

[4] A novel azelaic acid formulation for the topical treatment of inflammatory rosacea: A multicentre, prospective clinical trial