Jump to content

PubMed RSS Feed - -Ocular Comorbidities in Rosacea: A Case-Control Study Based on Seven Institutions


Recommended Posts

J Clin Med. 2021 Jun 29;10(13):2897. doi: 10.3390/jcm10132897.


Rosacea is a facial inflammatory dermatosis that is linked with various systemic illnesses. With regards to the eye, rosacea patients have been described to manifest ocular surface changes, such as blepharitis and conjunctivitis. However, studies that examine the association of rosacea with a wider array of ocular diseases are limited. Thus, our aim was to identify the range of ocular comorbidities in the Korean patient population and create a reference data set. A multi-institutional, case-control study was conducted, where 12,936 rosacea patients and an equal number of sex- and age-matched control subjects were extracted over a 12-year period. We were able to discover a notable association between rosacea and blepharitis (adjusted odds ratio (aOR) 3.44; 95% confidence interval, 2.71-4.36, p < 0.001), conjunctivitis (aOR 1.65; 95% CI, 1.50-1.82, p < 0.001), glaucoma (aOR 1.93; 95% CI, 1.70-2.20, p < 0.001), dry eye syndrome (aOR 1.89; 95% CI, 1.70-2.09, p < 0.001), and chalazion (aOR 3.26; 95% CI, 1.41-7.57, p = 0.006) from logistic regression analysis. Female subjects and individuals younger than 50 exclusively showed higher odds for chalazion. Our study suggests that ocular comorbidities (i.e., glaucoma, dry eye syndrome, and chalazion as well as blepharitis and conjunctivitis) are more prevalent among Koreans with rosacea. Clinicians should proactively check ocular symptoms in rosacea and employ joint care with an ophthalmologist in cases of need.

PMID:34209731 | DOI:10.3390/jcm10132897

{url} = URL to article

Other Systemic Comorbidities in Rosacea

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...

Important Information

Terms of Use