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Am J Ophthalmol. 2021 Dec 20:S0002-9394(21)00645-0. doi: 10.1016/j.ajo.2021.12.006. Online ahead of print.


PURPOSE: To report outcomes of tape splint tarsorrhaphy (TST) for persistent corneal epithelial defects (PCED).

DESIGN: Retrospective, interventional case series.

METHODS: Setting: tertiary cornea clinic.

INTERVENTION: consecutive patients with a PCED (≥14 days) treated at a tertiary cornea clinic with a TST.

STUDY POPULATION: Included were patients with a corneal epithelial defect that did not respond to treatment with a BCL. Excluded were patients with a follow-up time of less than three months.

MAIN OUTCOME MEASURE: time to PCED resolution.

RESULTS: Thirty-four eyes of 33 patients, mean age of 62.9±17.8 years (range 27 to 90 years) were included in this study. The main etiologies of the PCED were post keratoplasty (n=15), herpes simplex virus (n=4), superficial keratectomy (n=3), neurotrophic cornea (n=4), fungal keratitis (n=2), exposure keratopathy (n=2), failed graft (n=1), peripheral ulcerative keratitis (n=1), rosacea (n=1) and stitch abscess (n=1). Time from PCED presentation to TST was 58.9±106.3 days (range 14 to 390 days) with the area of the PCED being 25.1±15.7 mm2 (range 0.50 to 42.0mm2). Following TST, resolution of the PCED was achieved in 29/34 eyes (85.3%) without the need for additional interventions within 22.5±24.3 days (range 2 to 105 days). logMAR BCVA significantly improved from 1.11±0.41 to 0.83±0.70 (p=0.02). There were no complications attributed to TST and two patients elected to discontinue due to discomfort.

CONCLUSIONS: Tape splint tarsorrhaphy achieved resolution of PCEDs secondary to various etiologies in 85.3% of eyes with a significant improvement in vision demonstrated. This simple, inexpensive, non-invasive technique may be considered for patients with PCEDs.

PMID:34942108 | DOI:10.1016/j.ajo.2021.12.006

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