Root Admin Guide Posted April 14, 2022 Root Admin Report Share Posted April 14, 2022 Sirt7 "is member of the mammalian sirtuin family of proteins, which are homologs to the yeast Sir2 protein." [1] The "loss of Sirt7 alleviates the rosacea-like features in mice. Thus, we reveal a SIRT7-TLR2-NF-κB axis that can be targeted for the improvement of rosacea." [2] "Sirtuins are a family of signaling proteins involved in metabolic regulation." [3] "In summary, we demonstrate that loss of SIRT7 reduces embryonic viability and causes premature aging." [4] End Notes [1] Sirtuin 7, Wikipedia [2] PubMed RSS Feed - -Aging-conferred SIRT7 Decline Inhibits Rosacea-like Skin Inflammation via Modulating TLR2-NF-κB Signaling [3] Sirtuin, Wikipedia [4] The EMBO Journal (2016)35:1488-1503SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair Berta N Vazquez Joshua K Thackray Nicolas G Simonet Noriko Kane-Goldsmith Paloma Martinez-Redondo Trang Nguyen Samuel Bunting Alejandro Vaquero Jay A Tischfield Lourdes Serrano Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now