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Erythema of Rosacea: Validation of Patient's Self-Assessment Grading Scale.

J Drugs Dermatol. 2015 Aug 1;14(8):841-844

Authors: Tan J, Leoni M

Abstract
BACKGROUND: Facial erythema is a primary feature of rosacea. Currently, no validated scales exist that can accurately capture a patient's self-assessment of their own facial erythema. During phase 2 studies for brimonidine tartrate gel, a 5-point numeric rating scale was developed as a tool to allow subjects to provide an independent assessment of visible changes to the facial erythema associated with their rosacea.<br /> OBJECTIVE: The objective of this study was to validate the revised patient's self-assessment (PSA) scale and evaluate it for statistical reliability and validity in quantification of facial erythema of rosacea.<br /> METHODS: The validity of the PSA scale was evaluated by assessing the test-retest reliability, construct validity, and known-groups validity based on the data collected during a Phase 2b study on brimonidine gel for the treatment of persistent facial erythema of rosacea.<br /> RESULTS: Based on the results of this evaluation, this PSA scale demonstrated test-retest reliability, construct validity, and known-groups validity.<br /> LIMITATIONS: Study results are most generalizable to those with moderate to severe erythema.<br /> CONCLUSION: The PSA is an appropriate scale to assess facial erythema associated with rosacea.<br /><br /> <em>J Drugs Dermatol.</em> 2015;14(8):841-844.

PMID: 26267728 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26267728?dopt=Abstract = URL to article

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