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Dermatology. 2023 Nov 26. doi: 10.1159/000535034. Online ahead of print.

ABSTRACT

Background The association between rosacea and psychiatric comorbidity has been reported previously. However, there is a lack of general population studies about this subject area. Objectives To study the association between rosacea with depressive and anxiety symptoms at population level. Methods A clinical whole-body examination was performed by dermatologists for 1,932 subjects belonging to the Northern Finland Birth Cohort 1966 Study during the 46-year follow-up survey. The presence of depressive and anxiety symptoms was gathered by using validated Hopkins Symptom Checklist-25 (HSCL-25) included into the self-administered questionnaires. Binary logistic regression analysis was used to identify associations between rosacea and psychological symptoms. Results Rosacea was found in dermatological evaluation in 15.1% of the study subject (n=292). In logistic regression analyses, after adjusting for confounding factors, those with rosacea had 1.6-fold (OR 1.55, 95% CI 1.02-2.32) risk for psychiatric symptoms according to HSCL-25 when compared with controls. In separate analyses of HSCL-25 depression subscale, the risk was increased especially for depressive symptoms OR 1.56 (95% CI 1.10-2.18). Conclusions Patients with rosacea seem to have increased risk for depressive and anxiety symptoms also in general population. Physicians treating patients with rosacea should pay more attention to the psychosocial health of patients.

PMID:38008081 | DOI:10.1159/000535034

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