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Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application.

J Drugs Dermatol. 2015 Sep;14(9):964-8

Authors: Schulte BC, Wu W, Rosen T

Abstract
Azelaic acid is a complex molecule with many diverse activities. The latter include anti-infective and anti-inflammatory action. The agent also inhibits follicular keratinization and epidermal melanogenesis. Due to the wide variety of biological activities, azelaic acid has been utilized as a management tool in a broad spectrum of disease states and cutaneous disorders. This paper reviews the clinical utility of azelaic acid, noting the quality of the evidence supporting each potential use.

PMID: 26355614 [PubMed - indexed for MEDLINE]

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