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CONCLUSION: This study suggests that the AIF and BF supplements provide significant clinical benefits in the reduction of facial erythema and hyperpigmentation.  

Plast Reconstr Surg Glob Open. 2016 Sep; 4(9 Suppl): 25-26. Published online 2016 Sep 16. doi: 10.1097/01.GOX.0000511256.60478.59 PMCID: PMC5147057https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147057/
Abstract: The Efficacy of Two Melon-Derived Superoxide Dismutase/Wheat Gliadin Oral Formulae in the Treatment of Facial Skin Hyperpigmentation and Erythema
Cory S. Goldberg, BSc, MD, MASc and Joshua T. Gauci, MSc

We need more research on this.

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