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Book. 2017 06


Photosensitivity refers to various symptoms, diseases and conditions (photodermatoses) caused or exacerbated by exposure to sunlight. It is classified into the following groups: Primary photodermatoses: Polymorphic light eruption. Juvenile spring eruption. Actinic folliculitis. Actinic prurigo. Solar urticaria. Chronic actinic/photosensitivity dermatitis. Hydroa vacciniforme (associated with Epstein-Barr virus). Exogenous photodermatoses: Drug-induced photosensitivity: common photosensitising drugs are thiazides, tetracyclines, non-steroidal anti-inflammatory drugs (NSAIDs), phenothiazines, voriconazole, quinine, vemurafenib. Photocontact dermatitis: due to phototoxic chemicals such as psoralens in plants, vegetables, fruit; fragrances in cosmetics; sunscreen chemicals; dyes and disinfectants. Pseudoporphyria: induced by drugs and/or renal insufficiency. Photoexacerbated dermatoses: Lupus erythematosus. Dermatomyositis. Darier disease. Rosacea. Pemphigus vulgaris. Pemphigus foliaceus. Atopic dermatitis. Psoriasis. Metabolic photodermatoses (rare): Porphyria cutanea tarda. Erythropoietic protoporphyria. Variegate porphyria. Erythropoietic porphyria (Gunther disease). Genetic photodermatoses (very rare): Xeroderma pigmentosum. Bloom syndrome. Rothmund Thomson syndrome. Cockayne syndrome.


PMID: 28613726


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