rss Posted March 4, 2018 Report Share Posted March 4, 2018 Rosacea Pathogenesis. Dermatol Clin. 2018 Apr;36(2):81-86 Authors: Ahn CS, Huang WW Abstract Rosacea is a chronic inflammatory skin disorder that is not fully understood but involves the complex interplay of genetic factors, immune dysregulation, neurovascular dysregulation, presence of microorganisms, and environmental factors. Increased activation of the immune system occurs through multiple stimuli, including increased levels of cathelicidin and kallikrein 5, Toll-like receptor 2, matrix metalloproteinases, and mast cells within the skin. Their effects are enhanced by the presence of microorganisms and external triggers, such as UV radiation. PMID: 29499802 [PubMed - in process] {url} = URL to article Link to comment Share on other sites More sharing options...
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