Root Admin Guide Posted April 25, 2018 Root Admin Report Share Posted April 25, 2018 The investigators concluded that twice-daily dosing of oxymetazoline cream did not offer any significant improvements in clinical efficacy compared with once-daily dosing. Based on the study findings, oxymetazoline 1.0% once daily provided the optimal dosing regimen with respect to efficacy, safety, and tolerability, and was thus selected for evaluation in phase 3 clinical studies. Once-Daily Topical Treatment Effective for Rosacea-Associated Facial Erythema, Sheila Jacobs, Dermatology Advisor Reference J Drugs Dermatol. 2018 Mar 1;17(3):308-316.Phase 2 Randomized, Dose-Ranging Study of Oxymetazoline Cream for Treatment of Persistent Facial Erythema Associated With Rosacea. DuBois J, Dover JS, Jones TM, Weiss RA, Berk DR, Ahluwalia G. Link to comment Share on other sites More sharing options...
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