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Enhancing survival of Demodex mites in vitro.

J Eur Acad Dermatol Venereol. 2018 Jul 27;:

Authors: Shiels L, Foley R, Gatault S, Powell FC

Abstract
Demodex mites, D. folliculorum and D. brevis, are complex microorganisms ubiquitously present in the pilosebaceous units of adult human facial skin and form part of its normal microbiome. Although their potential for pathogenicity is not fully understood, an increased Demodex population is associated with some skin and ocular disorders such as rosacea, pityriasis folliculorum and blepharitis (1). Further in vitro/ex vivo studies would help to decipher their possible involvement in these conditions. However, as reviewed previously by our team, dermatologists/scientists face several challenges to study Demodex mites (2). Notably, practical difficulties in maintaining sufficient numbers of mites alive after removal from skin make it difficult to carry out experiments involving living mites in the laboratory setting. In order to prolong mite survival for ongoing experiments, we investigated the potential benefits of storing live mites in the laboratory at different temperatures. This article is protected by copyright. All rights reserved.

PMID: 30051504 [PubMed - as supplied by publisher]

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