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image courtesy of Royal Queen Seeds

"A study recently showed the efficacy of hemp seed oil to control the symptoms of dermatitis. Hemp seed oil contains stearidonic acid, gamma-linoleic acid, and oleic acid, which help reduce skin inflammation in conditions such as eczema and rosacea. Its content of polyunsaturated fatty acids, such as omega-6 and omega-3, improves blood circulation and vascular functionality even in the thin capillaries of our face. Plus, hemp seed oil contains vitamins that are essential for the skin, synergising with the other compounds to produce a more pronounced effect."

How Cannabis And Hemp Can Reduce Symptoms Of Rosacea, Cannabis Blog, Royal Queen Seeds

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A detailed report on cannabinoid signaling in the skin had this to say: 

"It has recently been shown that abuse of synthetic, hyperpotent cannabinoids (e.g., “Bonsai”, “fake weed”, “K2”, and “Jamaica”) can result in dermatological disorders, such as premature skin aging, hair loss and graying, or acne [88], indicating that cannabinoid signaling can profoundly influence skin biology."

"Importantly, with respect to the efficiency of PEA, human clinical data are also available. Indeed, the PEA containing Physiogel® A.I. Cream was found to alleviate itch in 14 out of 22 patients suffering from prurigo, lichen simplex and other pruritic diseases. Importantly, the same formulation was found to be effective in alleviating erythema, excoriation, scaling, lichenification, dryness, as well as pruritus in AD patients (ATOPA study). However, another vehicle controlled, randomized clinical trial involving a total of 100 subjects suffering from pruritic dry skin (ClinicalTrials.gov ID: NCT00663364) found that a PEA containing lotion was not significantly superior in alleviating itch as compared to its emollient vehicle."

PEA is Palmitamide MEA, a naturally occurring lipid compound that may act as an anti-oxidant and anti-irritant.

Molecules. 2019 Mar; 24(5): 918.
Published online 2019 Mar 6. doi: 10.3390/molecules24050918
Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Kinga Fanni Tóth, Dorottya Ádám, Tamás Bíró, Attila Oláh

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