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Global rosacea treatment guidelines and expert consensus points: The differences.

J Cosmet Dermatol. 2019 Feb 26;:

Authors: Juliandri J, Wang X, Liu Z, Zhang J, Xu Y, Yuan C

BACKGROUND: Rosacea is a highly prevalent, chronic inflammatory disease. The treatment of rosacea remains a challenge to dermatologists. Therapies include skin care, medications, lasers, and various combinations of these modalities. The appropriate treatment depends on clinical types and patient's various clinical symptoms.
PURPOSE: The purpose of this study was to review and compare current therapies for rosacea of all severities from four different guidelines.
METHODOLOGY: We searched PubMed using the keywords "rosacea," "treatment" AND ["erythema rosacea" OR "papulopustular rosacea" OR "ocular rosacea" OR "phymatous rosacea"]. We selected randomized controlled trials, observational studies, controlled clinical trials, and clinical trials. We indentified further studies (including the guidelines) by hand-searching relevant publications and included those that met the inclusion criteria.
RESULTS: The total number of records identified was 421. We limited our search to the specific abovementioned study types. Twenty-five of these studies met with our inclusion criteria. An additional five manuscripts were selected using the abovementioned method, and four guidelines were included in this review.
CONCLUSION: Diagnosing and choosing the appropriate treatment options of rosacea according to guidelines is the basis of scientific criteria. More large-scale randomized controlled clinical trials on new treatment methods, new drugs, or new dosage forms provide a new guideline for future rosacea treatment. Although there are some differences in the treatment of rosacea, it is generally based on anti-demodex, anti-inflammatory, and anti-angiogenesis.

PMID: 30809947 [PubMed - as supplied by publisher]

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