Frontal fibrosing alopecia

[Guide]

Frontal fibrosing alopecia may be a co-existing condition with rosacea, as well as, a systemic comorbidity in rosacea.  

One cross-sectional study including 99 women with Frontal fibrosing alopecia presented a higher prevalence of rosacea than did controls. [1]

"Frontal Fibrosing Alopecia is the frontotemporal hairline recession and eyebrow loss in postmenopausal women that is associated with perifollicular erythema, especially along the hairline. It is considered to be a clinical variant of lichen planopilaris. Frontal Fibrosing Alopecia has been most often reported in post-menopausal women with higher levels of affluence and a negative smoking history. Autoimmune disease is found in 30% of patients." Wikipedia

"Most of the patients in this series of FFA were postmenopausal women. The prevalence of oral and genital lichen planus was higher than that observed in the general population. Patients with a linear pattern had less severe disease. Facial papules were more common in younger patients and both facial papules and rosacea were associated with a greater need for oral treatment." [2]

"FFA seems to be associated with hormonal exposure (pregnancy, HRT and raloxifene), comorbidities (hypothyroidism, LPP and rosacea) and environmental factors (facial sunscreens, antiageing creams and occupational exposure). Further research is required to analyse the exact mechanism in which these environmental factors participate in the development of this alopecia." [3]

"The association with moisturizers, odinary facial soap, and hair straightening with formalin and the negative association with anti-residue / clarifying shampoo reinforce the possibility of an exogenous particle triggering FFA." [4]

Genetic and Rare Diseases Information Center (GARD) 

 

End notes

[1] A Cross-sectional Study of Rosacea and Risk Factors in Women with Frontal Fibrosing Alopecia.

J Acad Dermatol.VOLUME 78, ISSUE 3, P596-597.E1, MARCH 01, 2018
Frontal fibrosing alopecia and cutaneous comorbidities: A potential relationship with rosacea
Cristina Pindado-Ortega, MD, David Saceda-Corralo, MD, Diego Buendía-Castaño, MD, Ana R. Rodrigues-Barata, MD

[2] Frontal Fibrosing Alopecia: A Retrospective Study of 75 Patients.

[3] Risk factors associated with frontal fibrosing alopecia: a multicentre case-control study.

[4] J Am Acad Dermatol. 2020 Aug 21;:
Risk Factors for Frontal Fibrosing Alopecia: a case-control study in a multiracial population.
Ramos PM, Anzai A, Duque-Estrada B, Farias DC, Melo DF, Mulinari-Brenner F, Pinto GM, Abraham LS, Nogueira Santos LD, Pirmez R, Miot HA

Etcetera

Hair loss and rosacea

Eyebrows hairloss! Fixed the symptoms but no regrowth