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The Role of Topical Probiotics on Skin Conditions: A Systematic Review of Animal and Human Studies and Implications for Future Therapies.

Exp Dermatol. 2019 Sep 08;:

Authors: Knackstedt R, Knackstedt T, Gatherwright J

Abstract
There is increasing evidence that the intestinal microbiome plays an important role in modulating systemic inflammation and disease. Oral probiotics can modulate the intestinal microbiome and have demonstrated to be efficacious in treating topical skin conditions, such as atopic dermatitis, acne and rosacea. By proxy, exogenous application to the skin of probiotics should also promote a positive bacterial balance to mitigate or potentially eliminate pathologic conditions. The goal of this article is to provide a systematic review of studies that have investigated the role of topical probiotics in mitigating skin conditions. Additionally, skin conditions where dysbiosis have been identified but topical probiotics have not been investigated are discussed. We hope this review both analyzes the evidence for the role that topical probiotics could play in topical skin conditions, as well as highlights additional areas in need of research and exploration.

PMID: 31494971 [PubMed - as supplied by publisher]

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